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Karim Majzoub

@karimaj.bsky.social

Group leader @igmm-montpel.bsky.social studying viruses - ERC Stg- Amateur athlete and musician- Husband and father- Europtimist @biolum-montpellier.bsky.social https://www.igmm.cnrs.fr/en/team/rna-viruses-and-host-factors/

2,187 Followers  |  7,072 Following  |  174 Posts  |  Joined: 04.11.2023  |  1.8741

Latest posts by karimaj.bsky.social on Bluesky

Meet us in 2 days in Montpellier for the French-Japan Virology symposium!

07.10.2025 17:37 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Lead by postdoc in the lab Ruiqi Ge and in collaboration with Bob Coffey’s lab, we are happy to share rPAL-seq for rapid and sensitive sequencing based profiling of glycoRNAs @biorxivpreprint.bsky.social www.biorxiv.org/content/10.1...

06.10.2025 13:36 β€” πŸ‘ 41    πŸ” 19    πŸ’¬ 1    πŸ“Œ 4

Thanks Maria @morielab.bsky.social , first time I heard about this journal/platform was thanks to a paper from your lab ;)

04.10.2025 08:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
No evidence for human or rodent deltavirus replication in yeast | microPublication

New paper (micro) from our lab : β€œNo evidence for human or rodent deltavirus replication in yeast”. A collaboration with Dom helmlinger’s lab .

04.10.2025 06:55 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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Boa Constrictor Brain Cells Slither into Focus From reptiles and Tasmanian devils to humans, one researcher zooms in on unseen features of the brain and liver cells, like the cytoskeleton.

Our @viroscope.bsky.social Joe McKellar interviewed by The-Scientist Magazine ! Look at all these beautiful cells we have in the lab :)

03.10.2025 20:13 β€” πŸ‘ 9    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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🧬 π‹β€™πšπ«π­ 𝐝𝐞́π₯𝐒𝐜𝐚𝐭 𝐝𝐞 𝐟𝐚𝐒𝐫𝐞 𝐭𝐚𝐒𝐫𝐞 π₯𝐞𝐬 π πžΜ€π§πžπ¬
Des scientifiques de l'IGMM utilisent l’embryon de drosophile pour dΓ©montrer que la rΓ©pression de l’expression des gΓ¨nes est un mΓ©canisme beaucoup plus complexe qu’attendu.

πŸ“– πŸ‘‰ lnkd.in/dPqUREuf
πŸ“· Β© Mounia Lagha et Virginia Pimmett

30.09.2025 06:35 β€” πŸ‘ 6    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Meet us at Genopolys , Montpellier for a France-Japan virology workshop ! 9-10 october 2025 ! 2 exciting days with many viruses! Co-organized with @systemsvirology.bsky.social Kei Sato and Monsef Benkirane @igmm-montpel.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social

17.09.2025 08:56 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 2    πŸ“Œ 2
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Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail - Nature Communications Rodrigues and Queiroz et al. report the discovery of Naiavirus, the largest enveloped virus, isolated from a Brazil biome. With an oval capsid and flexible tail, its giant genome holds many novel gene...

Naiavirus: an enveloped giant virus with a pleomorphic, flexible tail
nature.com/articles/s41467-025-63463-6

17.09.2025 15:36 β€” πŸ‘ 48    πŸ” 28    πŸ’¬ 0    πŸ“Œ 3
Strengthening France-Japan Collaboration in Virology Let's come together to boost collaboration between France and Japan in the field of virology!

Registration link : www.eventbrite.com/e/billets-st...

17.09.2025 08:57 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Meet us at Genopolys , Montpellier for a France-Japan virology workshop ! 9-10 october 2025 ! 2 exciting days with many viruses! Co-organized with @systemsvirology.bsky.social Kei Sato and Monsef Benkirane @igmm-montpel.bsky.social @cnrsbiologie.bsky.social @umontpellier.bsky.social

17.09.2025 08:56 β€” πŸ‘ 11    πŸ” 5    πŸ’¬ 2    πŸ“Œ 2

hey bluesky πŸ‘‹ visa hurdles mean I’m looking for opportunities outside the US. I’m a computational biologist (bacterial + phage genomics, postdoc in Koonin’s group @ NIH). I am interested in teaming up on funding apps. reach out if this resonates!

15.09.2025 17:26 β€” πŸ‘ 70    πŸ” 91    πŸ’¬ 1    πŸ“Œ 3
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Endogenous viral elements in termite genomes reveal extensive diversity of deltaviruses and provide insights into their origins Deltaviruses are subviral agents of animals, which, in humans, require a hepadnavirus helper for transmission. The absence of deltavirus-like endogeno…

Endogenous Deltaviruses (EVEs) in termite genomes !

14.09.2025 05:09 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Student hostages in culture war | EMBO reports EMBO Press is an editorially independent publishing platform for the development of EMBO scientific publications.
10.09.2025 01:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

RIP

08.09.2025 02:06 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Get fucked, textbooks.

Seriously breaking my PhD in ecology and evolutionary biology brain that this happened.

www.nature.com/articles/s41...

06.09.2025 03:08 β€” πŸ‘ 78    πŸ” 19    πŸ’¬ 5    πŸ“Œ 8

New pre-print from Doudna lab members @erinedoherty.bsky.social & @jnoms.bsky.social ✨

Here we explore how recurrent adaptation of a single anti-defense protein fold enables evasion of distinct immune systems.

22.08.2025 19:36 β€” πŸ‘ 53    πŸ” 21    πŸ’¬ 0    πŸ“Œ 1
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RNA N-glycosylation enables immune evasion and homeostatic efferocytosis - Nature N-glycans on glycoRNAs prevent innate immune sensing of endogenous small RNAs, and the natural mechanism they use demonstrates how glycoRNAs exist on the cell surface and in the endosomal network without inducing autoinflammatory responses.

Nature research paper: RNA N-glycosylation enables immune evasion and homeostatic efferocytosis

go.nature.com/41x3bol

12.08.2025 19:30 β€” πŸ‘ 20    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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A trove of antiviral TRIM family E3 ligases in reptiles Many scaled reptiles (squamates) are exposed to flaviviruses but some, including iguanas, exhibit strong resistance to infection. To identify genes encoding viral resistance, we screened a cDNA librar...

Mining Iguana cDNAs for new immune proteins! Incredibly creative screen from Ian Boys and @elearlybird.bsky.social :

www.biorxiv.org/content/10.1...

12.08.2025 00:18 β€” πŸ‘ 19    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

Incredible discovery ! The first known role for sugar coated RNAs : immune evasion ! @raflynn5.bsky.social does it angain with @vinnieviruses.bsky.social @vijayrathinam.bsky.social and colleagues !

06.08.2025 18:52 β€” πŸ‘ 20    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
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RNA N-glycosylation enables immune evasion and homeostatic efferocytosis by chemically caging acp3U. Excited to report this work lead by Vinnie @vinnieviruses.bsky.social and in collaboration with @vijayrathinam.bsky.social in @nature.com www.nature.com/articles/s41...

06.08.2025 15:36 β€” πŸ‘ 108    πŸ” 46    πŸ’¬ 7    πŸ“Œ 2

Congrats

25.07.2025 16:54 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Proud of Roni , a PhD student from our lab !

07.07.2025 14:48 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Histone-mediated chromatin organization in prokaryotes and viruses Histones are fundamental chromatin-organizing proteins in eukaryotes and archaea, where they assemble into (hyper)nucleosomes that wrap DNA. Recent studies have expanded the known repertoire of histon...

A must-read for histone afficionados: our new review on 'Histone-mediated chromatin organization in prokaryotes and viruses' www.cell.com/trends/bioch... @samuelschwab.bsky.social @vikramalva.bsky.social

30.06.2025 07:35 β€” πŸ‘ 42    πŸ” 16    πŸ’¬ 0    πŸ“Œ 2
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The dangers of so-called AI experts believing their own hype Beware the tech leaders making grandiose statements about artificial intelligence. They have lost sight of reality, says Philip Ball

Beware the tech leaders making grandiose statements about artificial intelligence. They have lost sight of reality, says Philip Ball

07.07.2025 04:50 β€” πŸ‘ 10    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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A Boa Constrictor brain-derived cell expressing a viral glycoprotein (magenta) and stained for actin (yellow) and DNA (white).

#FluorescenceFriday

27.06.2025 11:20 β€” πŸ‘ 81    πŸ” 16    πŸ’¬ 1    πŸ“Œ 0
Logo of NSV2025 conference with a drawing of the Montpellier skyline

Logo of NSV2025 conference with a drawing of the Montpellier skyline

Arrived in Carcassone en route to Montpellier for the XIXth Negative-strand RNA
Virus Meeting

A community-driven & very positive conference all about RNA(-) viruses

Reach out if you’d like to chat - seeing old friends and meeting new people is always the best

www.negativestrandvirus.org/home

22.06.2025 14:05 β€” πŸ‘ 16    πŸ” 3    πŸ’¬ 0    πŸ“Œ 1
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An episodic burst of massive genomic rearrangements and the origin of non-marine annelids - Nature Ecology & Evolution An analysis of annelid genomes reveals massive reshuffling of chromosomes in the ancestral lineage leading to clitellates, a clade composed of non-marine annelids, with potential implications for the ...

Glad to see this paper finally out! An episodic burst of massive genomic rearrangements and the origin of non-marine annelids
@natecoevo.nature.com @ibe-barcelona.bsky.social @csic.es @erc.europa.eu www.nature.com/articles/s41...

18.06.2025 12:32 β€” πŸ‘ 79    πŸ” 39    πŸ’¬ 3    πŸ“Œ 4
RNA | Mobile

RNase L Produces tRNA-derived RNAs that Contribute to Translation Inhibition

10.06.2025 18:26 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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MagIC-Cryo-EM, structural determination on magnetic beads for scarce macromolecules in heterogeneous samples A technique that enables single-particle cryo-EM analysis of targets on a magnetic bead and a particle curation method that helps structural classification of small particles has been developed.
09.06.2025 18:55 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Micro-molΓ©cules, mΓ©ga-interrogations : c'est quoi ces "obΓ©lisques" qui intriguent les scientifiques ? On les appelle "obΓ©lisques". Ces molΓ©cules minuscules, comparables Γ  des virus mais beaucoup plus simples, constituent l'une des grandes dΓ©couvertes rΓ©centes et semblent omniprΓ©sentes dans notre organ...

🧬 Les obΓ©lisques, nouvelles molΓ©cules d’ARN circulaires, intriguent les chercheurs.
@karimaj.bsky.social en parle dans @france3occitanie.bsky.social & @GEO_fr πŸ‘‡
πŸ”— france3-regions.franceinfo.fr/occitanie/he...
πŸ”— www.geo.fr/sciences/les...

04.06.2025 13:37 β€” πŸ‘ 14    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0

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