Murillo R.

Just an absolutely horrific self own, depleting the US of amazing students from all over the world who contributed to what used to make America great: its diversity, its openness, and its leadership in education.

Because we are historians ourselves?

What if NIH had been 40% smaller? Replaying history with less NIH funding shows widespread impacts on drug-linked research

This may be the most important paper ever published about NIH funded research.

www.science.org/doi/10.1126/...

I just had to hop through 5 papers to find the original methods (2025 -> 2018 -> 2014 -> 2013 -> 2005). what is your highest score? 🤯

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

I literally spent 10 min translating Lula’s speech about Palestine to English. I just need every single one of my gringo friends to listen to this man in order to maybe restore their faith in politics. This right here is a politician. This is why we voted for him. And personally, I’ll do it again.

We are excited to share GPN-Star, a cost-effective, biologically grounded genomic language modeling framework that achieves state-of-the-art performance across a wide range of variant effect prediction tasks relevant to human genetics.
www.biorxiv.org/content/10.1...
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Our paper Genomic diversity of the African malaria vector Anopheles funestus was published in Science today! It features inversions, selection in action, museum specimens and putative new ecotypes. doi.org/10.1126/scie...

evergreen

It's 2025, so I feel like it's a stretch to slice the analyses of the same handful of genomes into three or more papers...

this keeps me up at night. I can’t imagine monkeys surviving the 2800km trip from Africa to South America…

Homepage - Population, Evolutionary, and Quantitative Genetics Conference Visit our website to learn more.

Save the date! #PEQG26 June 9-12 2026 in Asilomar, CA. Happens only every 2yrs, but is my favorite conference. Full website coming soon, and registration and abstract submission opens November 14, but I'm allowed to tease that keynotes will be @jnovembre.bsky.social @jennytung.bsky.social and me!

SimHumanity: Using SLiM 5.0 to run whole-genome simulations of human evolution The reconstruction of human evolutionary history has undergone repeated advances, each made possible by methodological innovations. In recent decades, genetic and genomic data played a central role in...

Announcing SimHumanity, a baseline SLiM 5.0 model of the full human genome, replete with demographic history, autosomes, X/Y, and mtDNA. A shared starting point for reproducible evolutionary simulations. We’d love your feedback! #SLiM #evolution #genomics www.biorxiv.org/content/10.1...

Collateral mutagenesis funnels multiple sources of DNA damage into a ubiquitous mutational signature Mutations reflect the net effects of myriad types of damage, replication errors, and repair mechanisms, and thus are expected to differ across cell types with distinct exposures to mutagens, division ...

In these dark times, it comes as a rare pleasure to highlight @natanaels.bsky.social ‬ & @marcdemanuel.bsky.social's work on germline and somatic mutations in humans. 1/n
www.biorxiv.org/cgi/content/...

Why do males and females often differ in traits?
The expected answer: selection.
But our new paper in GENETICS shows that genetic drift alone can generate sexual dimorphism — even when male & female optima are the same

#NIH is hanging by a thread. The #CDC has been decimated. #RFK Jr. and Russell #Vought are psychopaths--I don't say this frivolously--they are cold, calculating, inflicting violence on millions through public policy. It is where we are right now. These men are not normal. 1/

I think Andy/Scott/Angel were looking into linked short reads (universalsequencing.com/pages/tell-s...) for phasing barnacle genomes (high diversity, not as messy, probably).

Genomics hivemind: I want to genotype a bunch of diverse, heterozygous diploids with a messy genome (🌽 -- who'd have guessed?) but I care about phase. Computational phasing doesn't really cut it, so wondering what the cheapest alternatives are -- nanopore to 10-20X? Linked shortreads?

tskit_arg_visualizer: interactive plotting of ancestral recombination graphs Summary: Ancestral recombination graphs (ARGs) are a complete representation of the genetic relationships between recombining lineages and are of central importance in population genetics. Recent brea...

Excited to share our new preprint for the tskit_arg_visualizer Python package! ARGs can sometimes feel like a black box, so
@yanwong.bsky.social and I have been developing a method to programmatically drawing these graphs.

🔗 arxiv.org/abs/2508.03958

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1. The philosophy of science sometimes gets an unearned reputation as a purely academic exercise that offers little by way of concrete tools for advancing research.

This is wrong.

And today, as we grapple with how AI is changing the nature of scientific activity, it's desperately wrong.

Postdoctoral Scholar – Genomics, Aging, Somatic Mutation, Structural Variation, Evolution , Cancer – Integrative Biology University of California, Berkeley is hiring. Apply now!

The Sudmant lab at UC Berkeley is seeking a postdoc to work on a fully funded NIH project to understand differences in DNA repair and somatic mutation across the primate tree of life. Please spread widely to those who may be interested aprecruit.berkeley.edu/JPF05052

Incredibly proud of this work where we developed a method for understanding the information contained in millions of genomes. Another example of NIH funded research.

Hello bluesky community!

I'm hiring a postdoc to do machine learning in population genetics.
Starting to build up a lab at Indiana University Bloomington where I just started a faculty position.
Apply with the below link: indiana.peopleadmin.com/postings/30325

Logo for the Genomic History Inference Strategies Tournament.

If you're new to demographic history inference from population genomics, try this webapp I created to illustrate how dadi fits bottleneck models to site frequency spectra: ryangutenkunst-dadi-two-epoch.hf.space . It even outputs files for submitting to the GHIST competition! ghi.st

Seeking a few Postdoctoral Researchers at Mathematical Genomics RIKEN ECL Research Unit (25-695)

Postdoc position in my group in Tokyo!
Please get in touch if you are interested.

And happy to discuss projects - these would range from developing new methods to analysis of new genomes that we are now sequencing in the lab.

Job Ad: www.riken.jp/en/careers/r...
Lab page: speidellab.github.io

New preprint: we advertise DAFNEE, a database of academia-friendly eco-evo-archaeo journals. 1/6
#AcademicPublishing #ecoevo #archaeology #EthicalPublishing #SocietyJournals #DiamondOpenAccess
doi.org/10.32942/X24...

GenDivRange: A global dataset of geo-referenced population genetic diversity across species ranges - Scientific Data Scientific Data - GenDivRange: A global dataset of geo-referenced population genetic diversity across species ranges

GenDivRange: A global dataset of geo-referenced population genetic diversity across species ranges #popgen #consgen www.nature.com/articles/s41...

Excited for our publication on how the geographic scale of a sample affects the discovery of rare, deleterious variants to be out this week. With a mix of theory, simulation, and data analysis, we show when samples are narrow vs broad, the number of variants discovered and their frequencies change

congrats, @jeffspence.github.io! looking forward to all the cool science that will come out of your lab :)

Reminder that SSE members in Brazil, Colombia, Mexico, India, and 152 low-income countries around the world can still get FREE registration for the virtual Evolution meeting! Please share with your colleagues: www.evolutionsociety.org/index.php?mo...