My first Bluesky paper post! Iβm pleased to announce the publication of our single-nucleus atlas of adult neurons from wild-type and long-lived, better performing insulin receptor (daf-2) mutants, by Jon St. Ange and Yifei Weng et al.DOI: 10.1016/j.xgen.2024.100720
05.12.2024 14:19 β π 649 π 52 π¬ 24 π 5
Please add me!
06.12.2024 09:49 β π 1 π 0 π¬ 1 π 0
More great work by Mirre!
28.11.2024 15:03 β π 1 π 0 π¬ 0 π 0
I found this out while reading for a historical review, even many classical articles on the field of medical sciences are simply not available, which I did not expect.
27.11.2024 09:21 β π 0 π 0 π¬ 0 π 0
I double on that. Seems like a topic that has unfortunately been missing in conferences I have attended to this year.
26.11.2024 23:14 β π 1 π 0 π¬ 1 π 0
Welcome here!
25.11.2024 23:02 β π 1 π 0 π¬ 0 π 0
THank you for making this happen. Could you add me?
25.11.2024 23:00 β π 1 π 0 π¬ 1 π 0
Very cool Tim! I am starting to make publication on the app, if you could add me it would be awesome. Perhaps my publications were not carrying the proper terms for your filter too?
25.11.2024 20:12 β π 1 π 0 π¬ 1 π 0
What would you recommend to a newbie by Borges, Cortazar and Asimov. I can read in Spanish so I suspect I will gravitate towards the original versions.
24.11.2024 23:29 β π 1 π 0 π¬ 1 π 0
This is the first strong evidence showing that caloric restriction can significantly increase maximum lifespan in rodents (1935). This is a modified version of the classical tab, designed for easier readability. Whether or not you work on dietary restriction, what stands out to you in these results?
24.11.2024 23:25 β π 1 π 0 π¬ 0 π 0
Could I be added to the Starter Pack as well? Thanks!
24.11.2024 18:29 β π 0 π 0 π¬ 1 π 0
Big update to the Aging Research starter pack. Many new folks joining every day, so challenging to keep up. Related starter packs by @brunetlab.bsky.social and @paigeonthebrain.bsky.socialβ¬. Networks are built by self-reinforced expansion and amplification.
go.bsky.app/PcreQSa
23.11.2024 20:19 β π 47 π 14 π¬ 10 π 0
Thanks Patrick, this is awesome. Very useful efforts to grow the network in the platform.
23.11.2024 20:32 β π 1 π 0 π¬ 0 π 0
For similar topics, I recommend following accounts like @agingdoc.bsky.social @willmair.bsky.social @brunetlab.bsky.social @ctmurphy1.bsky.social @thevilchezlab.bsky.social @jorisdeelen.bsky.social @korolchuklab.bsky.social @mirresimons.bsky.social @dvalenzano.bsky.social
22.11.2024 23:27 β π 3 π 0 π¬ 1 π 0
Since Weismann, breakthroughs in our understanding have largely come from the work of Haldane, Williams, and Hamilton. Yet, much remains to uncover. Yet hereβs an old letter by Weismann I found in a German antique shopβone of my treasured discoveries.
22.11.2024 23:27 β π 0 π 0 π¬ 1 π 0
Weismann proposed that aging evolved through group selection. He argued that aging is selected to eliminate old individuals, thereby improving the population's overall health. Critics later highlighted the circularity of the argument: if aging didnt exist, there would be no individuals to remove π§΅
22.11.2024 23:27 β π 0 π 0 π¬ 1 π 0
What was Weismann thinking? He observed that smaller creatures often live shorter lives, while flying animals tend to live longer. Fascinated, he offered his own explanations and even predicted a limit to how many times somatic cells could divide (the Hayflick limit)π§΅
22.11.2024 23:27 β π 0 π 0 π¬ 1 π 0
However, the publication above is rather the essay itself. The first publication of his assay was published by the Society which hosted the event, in the Tageblatt der 54. Versammlung Deutscher Naturforscher und Γrzteπ§΅
22.11.2024 23:27 β π 0 π 0 π¬ 1 π 0
Weismann wrote in German, which was a leading language in biological thought during the 1880s. His first exploration on aging, titled 'On the Duration of Life', was presented at the Assembly of German Naturalists/Physicians on September of 1881. Iβm fortunate to own an original copy π§΅
22.11.2024 23:27 β π 1 π 0 π¬ 1 π 0
Why do living things age? Have you heard of August Weismann? As someone passionate about the evolutionary biology of aging and the history of the field, I thought my first Bsky should highlight himβthe first to propose Darwinian ideas on how aging might be shaped by natural selectionπ§΅
22.11.2024 23:27 β π 2 π 0 π¬ 1 π 0
Aging starter pack!
go.bsky.app/5UXXaDA
22.11.2024 04:23 β π 98 π 47 π¬ 24 π 3
ππΌββοΈ
22.11.2024 07:34 β π 0 π 0 π¬ 1 π 0
This is very interesting. While I have not studied the rise of Hitler in detail, I have heard that, in hindsight, the chain of events leading to it seems clear. However, the book Berlin Diary highlights how, when living through such events, their significance is not always immediately apparent.
21.11.2024 19:45 β π 20 π 0 π¬ 0 π 0
This is very interesting. While I have not studied the rise of Hitler in detail, I have heard that, in hindsight, the chain of events leading to it seems clear. However, the book Berlin Diary highlights how, when living through such events, their significance is not always immediately apparent.
21.11.2024 19:44 β π 1 π 0 π¬ 0 π 0
ππΌββοΈ
21.11.2024 19:34 β π 0 π 0 π¬ 0 π 0
Dr. rer. nat. | Bioinformatician 𧬠|
Exploring Aging & Longevity with Machine Learning π | Unraveling Life's Code | C.elegans | Consultant
UCL Institute of Healthy Ageing, Using Drosophila to understand neurodegenerative diseases
Computational biologist using omics data (imaging, gene expression) to investigate the impacts of environmental contaminants on biological systems
Group Leader @EMBL-EBI (www.ewaldlab.org)
Scientist investigating the mechanisms of brain aging. Not letting life pass me by.
@Buck Institute, formerly @Brown University.
https://www.buckinstitute.org/lab/webb-lab/
Professor and leader of the Autophagy Research Group at UiT The Arctic University of Norway. Engaged in curiosity driven basic research into molecular mechanisms and roles of selective autophagy in cell signaling and disease mechanisms.
Professor of Medicine @UCLA
Director @UCLA Liver Research Center
Quit clinics for research π¬ **My Views!**
ππΌ Autophagy and acidic organelles
ππΌ MASLD spectrum - HCC newbie
ππΌ Biology of aging
ππΌ Guitar
Scientist, writer interested in aging biology, criminal justice, wildlife, birds, the universe.
Author, Animal Liberation, Practical Ethics, The Life You Can Save, The Most Good You Can Do, Animal Liberation Now.
Podcast: "Lives Well Lived"
AI Persona: PeterSinger.ai
Professor of Bioethics, Emeritus, Princeton University.
Assistant Professor, Dept. of Nutritional Sciences, UW-Madison. Metabolism, RNA, and aging. All opinions my own (and not my employers).
The official Bluesky account of AGE. #geroscience #aging #AGE2025
https://www.americanagingassociation.org/
Geneticist, Professor at UCL, Secondment at Francis Crick Institute.
fission yeast | turquoise killifish | cellular quiescence | aging | functions of understudied genes and non-coding RNAs
organismal biologist & geneticist | PI at med school in Houston | amazed by microbial superpowers | he/him
#microbiome #Celegans #spacebiology #firstgen π§« π¦ π§ͺ π§¬
GS: https://bit.ly/goog-schol-buck-sam
ORCID: 0000-0002-4347-3997
Geneticist at University of Oregon @uoregon. Worms, C. elegans, aging, evolution, genetics, genomics, complex traits. Former provost and interim president. Lab: https://pages.uoregon.edu/pphil/ GScholar: https://scholar.google.com/citations?user=JbH6mVkAAA
βLearning that weβre only immortals for a limited timeβ
Neurobiologist turned into Aging researcher. EMBO Member. DORA Executive Board. Views my own.
Universidad de Chile
Geroscience Center for Brain Health and Metabolism (GERO)
The Buck Institute
Benvinguts a la #UniBarcelona, una porta al coneixement i a les experiΓ¨ncies a la primera universitat de Catalunya. Lβobres amb nosaltres?
Normes dβΓΊs de les xarxes socials: https://web.ub.edu/avis-legal
Postdoc in the @antebilab.bsky.social at @mpiage.bsky.social, in collaboration with the Mair Lab at Harvard SPH www.hsph.harvard.edu/mair-lab | Reproductive aging, ribosomes & RNA | Supported by GCRLE https://gcrle.org/ | π©π»βπ¬π§¬ she/her