Paul [Atreides] Wood

This scientist found a new trick of the immune system by digging through cellular rubbish Yifat Merbl is part of Nature’s 10, a list of people who shaped science in 2025.

When biologist Yifat Merbl and her team investigated cellular recycling centres known as proteasomes, they uncovered an entirely new part of the immune system

A proteasome chops proteins into smaller peptide fragments. When cells are infected with bacteria, it switches output to make antimicrobials

ScotRail has new AI announcer after 'stolen voice' row The new voice was built using recordings from a ScotRail employee following an ethics complaint.

Inviting Scotrail to roundly go and fuck themselves just as much as I’d invited them to before.

Just because you found a staff member willing to fuck over voice actors and effectively scab for your use of this dogshit gimmick does not mean you’ve done anything meaningful here.

Cunts the lot of ye

Telic-Alcatel Minitel 1B arrived in pieces, I've decided to take the hit and try to repair it. There's no way I'm shipping back to be destroyed and thrown away.
Wish me luck 🤞

Tortie kitten Jimmi Pickles and orange kitty benne staring at orange creamsicle cat mccavity and his pal, grey and white tabby tobin, outside cats who come by for treats

When the boys are back in town

WTF

House Dems on the oversight committee have received 95,000 new photos from Jeffrey Epstein's estate.

They just released 19 of them, featuring people like:

Donald Trump
Bill Clinton
Steve Bannon
Bill Gates
Larry Summers

“I had word from The Trump admin that theyre on top of things,” Mr. Tate wrote to someone close to him, in a message reviewed by The New York Times. “Ive been told ill be free soon but Trump needs to see me in Miami,” he added. The next month, an extraordinary order came down from the highest levels of the Romanian government, a Times investigation found. The prosecutors were told to find a compromise with the Tates. Despite their misgivings, they lifted the travel restrictions, a move that Romania’s prime minister thought would appease the Trump administration. “We’re massively back,” a grinning Mr. Tate announced in a video recorded for his followers on Feb. 27, as a private plane whisked the brothers to Florida.

They are "accused of coercing women into pornography. Andrew was also accused of rape and of having sex with and beating a 15-year-old."
After the Trump administration pressured Romania, they were allowed to leave.
www.nytimes.com/2025/12/10/u...

This is Charles Clyde Ebbets, the photographer who took the iconic “Lunch atop a Skyscraper” picture. Look at this fearless, dapper fuck wearing spats, suspenders, and a tie 850 feet above the ground. Absolute legend.

Throwback to the Xmas when I spoofed mobile game ads too accurately, and no one clicked on the video.

Absolutely no pressure, as you know, but I'm watching my Xmas waistline expand* and thinking "...hmmm. Hmmm!"

*mince pies, my kryptonite

We live in such a goofy dystopia.

Suspected Charlie Kirk assassin makes first in-person court appearance The Utah man charged with killing Charlie Kirk made his first in-person court appearance Thursday as his attorneys pushed to further limit media access in the high-profile criminal case.

It’s kind of incredible how little has been published about this guy and how little conservatives seem to care. Did people just forget these people were screeching for civil war when they thought he was a liberal?

Gamers that care about privacy and security need to start demanding that game studios ensure their games run perfectly on Steam Machine.

Steam Machine is providing us with the strategic opportunity to move millions of people away from Windows and onto Linux.

We need to leverage this opportunity.

Apparently this is the last day! Murderbot plus Witch King and more Humble Bundle! 14 books total and charity is World Central Kitchen.

orange cat on a pink blanket looking cute

a little sweetie watch has been issued for my local area

Trying to cheer up a friend who got a rejection by pointing out more people have read her submission than Nuzzi's book

@chompmancobra.bsky.social Hey, you still thinking of having people along on a walk? Probably next year now, obvs

Radio Magazine cover from December 1924 showing Santa Claus flying a biplane with overlarge radio equipment over a snowy town.

Covers, ads, and illustrations like these are part of our shared cultural heritage, and their preservation lets us experience not only Christmases past but also the media that shaped them.

Vintage 1920 advertisement showing Santa Claus reclining against a brick chimney, smoking a cigarette. He wears a red suit and black boots, with a night sky and evergreen branches in the background. A pack of Murad “The Turkish Cigarette” peeks out of his sack of presents with holly and wrapped gifts. Large text at the top reads “MURAD THE TURKISH CIGARETTE,” and smaller text at the bottom reads, “What could you enjoy more this Xmas than Murad?”

🧵 It’s the holiday season. Santa Claus is an icon of that history, but he wasn’t always reaching for a soda. 🎅

Unwrap more vintage Holiday magazine art & more in our collection ⤵️
archive.org/details/@ias...

#HolidayArt #PeriodicalArt #Archives #CulturalMemory #ChristmasHistory #PrintCulture

In full transparency our attorneys advised against holding his family ransom until he met the original deadline, but what we thought of as “breakthrough motivational techniques” they described as “a felony”.

Newton was a soyboy CONFIRMED.

Manchester Evening News: “Man dies after falling from lamppost putting up Union Jack flag Paul Lumber died after falling from a ladder while hanging Union Jack flags on lampposts near his home”

Please lower your flags to half-lamppost in respect.

🚨 BREAKING: Democrats on the House Oversight Committee have just released new photos from the Epstein Estate, including images of Donald Trump, Steve Bannon, Bill Gates, Bill Clinton, and Larry Summers.

the subeditor preparing this for publication like

A screenshot from The Game Awards Twitter Account. The text reads: Hogwarts Legacy is free this week on the Epic Games Store. Play two hours before the offer ends on December 18 to unlock the Harry Potter themed Chocolate Frog Back Bling in @Fortnite . Link to Hogwarts Legacy Epic Store Page. - Image is of a frog from the Harry Potter series with Hogwarts Legacys' cover art behind it. The text on the image says: "Play Hogwarts Legacy for free on Epic Games Store through December 18th. Get a Chocolate Frog Back Bling in Fortnite."

Fuck Fortnite, Fuck Epic, Fuck The Game Awards.

Posting this to their X but NOT their Bluesky just SHOWS they know they're doing some bigoted shit & just don't wanna get called out for it.

Imagine hurting your Transgender playerbase like this? And your Transgender viewers {In the case of TGA}?

New photos released from Epstein’s estate showing Trump, Bannon, Bill Clinton and other high-profile people | CNN Politics Democrats on the House Oversight Committee have released photos from Jeffrey Epstein’s estate Friday showing the many powerful figures in the late sex trafficker’s orbit, including President Donald Tr...

"One image released Friday shows what appears to be a bowl of novelty condoms with a caricature of Trump’s face...Another showed Trump with six women with leis whose faces were redacted by the committee."
www.cnn.com/2025/12/12/p...