Comparison of place field detection methods and their effect on place field stability and drift in mouse dCA1 for freely moving 1-photon imaging data

Next-generation multicolor indicators for in vivo imaging of norepinephrine - Nature Methods Improved red and green indicators for norepinephrine and their characterization are reported. These indicators allow detection of norepinephrine release in awake behaving mice in dual-color fiber phot...

The most sensitive green and red #norepinephrine #sensors engineered to date are out in #naturemethods! Deeply grateful to all our funders and contributors who made this work possible. A true team effort. @erc.europa.eu @snsf.ch doi.org/10.1038/s415...

Agree this is a very cool paper.

The result is that soma-dendritic mismatch reflects an error (teaching) signal.

Below panel (5e) is key data, supporting the idea that their SD residual approach captures differences in their two populations as a function of the behavioral outcome (error).

We are #hiring 2 PhD students at the University of Oslo! 🇳🇴
1️⃣ Systems Neuro: Spatial memory & addiction
2️⃣ Neuro/Cancer: Glioblastoma invasion.

Details: vervaeke-lab.org/Hiring
Please RT! 🔄 @UiO_LifeSci #Neuroscience #PhD #SystemsNeuro #Glioblastoma

You know what? For €25, this is not a bad way to add a digital read-out to a stereotaxic frame.

I'm measuring about a 20 micron discrepancy per millimeter between the DRO and the stereotax; not terrible.

#neuroSkyence 🧠

We had a lot of fun doing these experiments! Theta sweeps in MEC and internal direction signals in parasubiculum track moving objects during pursuit and reverse during backward movement. Simultaneously recorded HD cells in other areas remain locked to head direction across behaviors:

A split view of a single PDF document. Two different pages from the same document are shown

Maybe this isn't new, but I just noticed in the new @zotero.org version 8 that you can do split view of a PDF. Really nice feature for quickly checking results against methods

Projection-specific integration of convergent thalamic and retrosplenial signals in the presubicular head direction cortex Nonlinear dendritic integration in single presubicular neurons provides a mechanism for combining vestibular-based head-direction signals and visual landmark signals to anchor the brain’s internal com...

Coincidence of thalamic HD signal and retrosplenial visual input is detected in the Presubiculum! 🎯 This may be the neuronal basis for landmark anchoring of the HD signal. Pleased to announce the VOR is now available elifesciences.org/articles/92443 Congrats first author Louis Richevaux 🙌

Awn

Will this show up in the lab - or home use?

Congratulations Nao!

I am really proud that eLife have published this paper. It is a very nice paper, but you need to also read the reviews to understand why! 1/n

Time, space, memory and brain–body rhythms - Nature Reviews Neuroscience Understanding how the brain represents experienced time and how representations of space and time are integrated to form episodic memories has been a goal of much neuroscientific research. In this Per...

Time, space, memory and brain–body rhythms
www.nature.com/articles/s41...
#neuroscience

Macrophages excite muscle spindles with glutamate to bolster locomotion - Nature A population of macrophages with exclusive molecular and functional signatures in the muscle spindles express machinery for synthesizing and releasing glutamate, and a cellular component, the muscle s...

Surprising immune-neural function shown by Simone at the Imperial College London!
www.nature.com/articles/s41...

Funding wise, this seems to be my year 💪🤩

Now setting up an interdisciplinary convergence environment to figure out mechanisms of OPRM1 mutation & importance for addiction

Co-PIs @koenvervaeke @deopandey @osmangani

www.uio.no/english/rese...

Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...

How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social)
doi.org/10.1101/2025...

Postdoctoral Research Fellowship (286516) | University of Oslo Job title: Postdoctoral Research Fellowship (286516), Employer: University of Oslo, Deadline: Wednesday, October 15, 2025

Please RT
2 new positions in the lab as postdoc & PhD!

Interested in stress, pain, or reward? This project has it all!

We are a friendly but ambitious group. Oslo is a capital city on the fjord & bordered by forest, great urban & outdoors opportunities: 💃 ⛷️ 🚣 🎭 🎶

www.jobbnorge.no/en/available...

Branch logic: Dendritic computations diversify inhibition Long known for different circuit roles, parvalbumin and somatostatin interneurons are shown by Morabito et al.,1 in this issue of Neuron, to differ in…

🧪 We got the privilege to write a Preview on the beautiful work of Morabito, Zerlaut, Rebola and colleagues that was recently published in Neuron. www.sciencedirect.com/science/arti...

Ripple contributions to human memory: making the spiking content count - Nature Reviews Neuroscience In animal models, transient high-frequency oscillations in synchronized neural activity, known as ripples, have been linked to memory. Reithler et al. assess the current evidence for a contribution of...

Ripple contributions to human memory: making the spiking content count — a Review by Joel Reithler, Kelsey K. Sundby & Kareem A. Zaghloul

www.nature.com/articles/s41...

#neuroscience #neuroskyence

Hierarchical processing of sensory information across topographically organized thalamocortical-like circuits in the zebrafish brain Thalamocortical projections contribute to the spatial organization and functional hierarchies of the mammalian cortex. Primary sensory cortices receive topographically segregated information from firs...

Check out this exciting study led by Anh-Tuan Trinh from our lab, where we investigated how thalamocortical-like circuits in the zebrafish pallium receive, represent, and integrate sensory information:
🔗 doi.org/10.1101/2025...

Human intelligence is overrated and not a useful yardstick for AI - a polemic. markusmeister.com/2025/09/15/w...

A neural manifold view of the brain Nature Neuroscience - Recent advances in neuroscience have revealed how neural population activity underlying behavior can be well described by topological objects called neural manifolds....

This type of textbook chapter review of neural manifolds has been so needed. Thank you for writing this. It's excellent.

rdcu.be/eGjAu

Our first steps into sensory processing is now online!
Work spearheaded by Rejwan Salih from experiments by @prime5222.bsky.social and François Pauzin
We were lucky to receive guidance from Davide Zoccolan on the analytical methods.
#neuroskyence

Phd candidate or postdoc– Genetic determinants of opioid responsiveness The Department of Research and Development at the Division of Emergencies and Critical Care, Oslo University Hospital in collaboration with Leknes Affective Brain lab (www.affectivebrains.com) and the...

What can *genetic insensitivity to opioids* teach us about endogenous opioid function in humans?

Fully funded position in Oslo (PhD student or postdoc)

Interested in pain, mu/kappa opioids, behavioural genetics, RCTs, or related? Apply here:
2411.webcruiter.no/Main2/Recrui...

Please RT for reach

This comment is 3 minutes long, and it's from back in February. It bears repeating.

"Curiosity-driven, peer-reviewed research is not meant to pass the politician's test."

x.com/RepAuchinclo... (1/2)

Can't wait to read this preprint from Misha Ahrens and team. Calcium imaging in larval zebrafish, in every cell in the body! Amazing.

www.biorxiv.org/content/10.1...

Diatoms?

A piece of neuroscience history. The original "Oslo chamber", possibly the first one to be used for holding brain slices.

Has anyone got any experience with gcamp8 transgenic mice yet? Eg the Thy1-GCaMP8s line?

janelia.figshare.com/articles/dat...

Direct entorhinal control of CA1 temporal coding Nature Communications - Temporal coding in the hippocampus is thought to be key for memory and predictions. Here, the authors show that blocking one entorhinal input affects two aspects of...

Our collaboration - from PhD work - examining input-specific (EC L3) contributions to rate and temporal coding in CA1 place cells is now out in @natcomms.nature.com 🔬🧠

rdcu.be/evWtz