Pub of the Month! 📄💜
This month’s feature: “Comparative analysis of human and mouse ovaries across age” from the Laird Laboratory @ucsanfrancisco.bsky.social
Celebrating the research (and researchers!) moving science forward. 🔬🥼✨
#ReproRocks #WinRS #NewPublication #Research #SSR #Science
31.10.2025 17:59 — 👍 2 🔁 2 💬 0 📌 0
Here’s to unraveling the mysteries of reproduction one (spooky) experiment at a time! 👻🧪
31.10.2025 18:00 — 👍 2 🔁 1 💬 0 📌 0
Selective RNA sequestration in biomolecular condensates directs cell fate transitions - Nature Biotechnology
Stem cell differentiation is controlled by manipulating RNA condensates.
SOOOOO proud of our amazing grad student Mika! 👏 👏👏Congrats to
@distefanolab.bsky.social
and @brumbaugh-lab.bsky.social for their manuscript describing how biomolecular condensates direct cell fate!
@natbiotech.nature.com www.nature.com/articles/s41...
28.10.2025 15:38 — 👍 2 🔁 0 💬 0 📌 0
Going to the SSR annual meeting and need childcare support? Apply for a childcare grant through WinRS! #momsinstem #happymothersday
12.05.2025 17:34 — 👍 4 🔁 1 💬 0 📌 0
Attention SSR Annual Meeting attendees:
Don't miss registration for the Lunch and Learn session with Dr. Kelly Diggs to sharpen up your mentoring skills!
#reprorocks #womeninstem
29.05.2025 20:37 — 👍 5 🔁 3 💬 0 📌 0
#womenshistorymonth #womeninstem
04.03.2025 22:16 — 👍 10 🔁 2 💬 0 📌 0
Listen to 2024 Roger V Short Medal Awardee, Dr. Francesca Duncan, discuss ovarian aging and give trainees a bit of her wisdom on the latest SSR podcast! 👏👏👏
#womeninSTEM #reprorocks
Listen to the full episode here 👇https://www.buzzsprout.com/1786803/episodes/16143433
16.01.2025 16:41 — 👍 7 🔁 5 💬 0 📌 0
Working model of the impact of Slc25a1 deficiency on placental and embryonic cardiac development. In the normal placenta (left), SLC25A1 facilitates the transport of citrate from mitochondria to the cytoplasm. Citrate is converted into acetyl-CoA, which is essential for maintaining H3K27ac and promoting the differentiation of trophoblast cells. Trophoblast cells secrete PSG proteins, supporting normal placental and embryonic heart development. In the absence of Slc25a1 (right), citrate cannot be transported from mitochondria to the cytoplasm, resulting in a reduction in acetyl-CoA levels. This leads to reduced deposition of H3K27ac at the promoter and enhancer regions of key factors involved in trophoblast differentiation and Psg genes, thereby affecting the expression levels of these genes and causing abnormal placental development, which in turn leads to conotruncal defects and thinner ventricular walls in mouse embryonic hearts.
Wenli Fan et al. leverage conditional mouse knockouts to explore the link between placental problems and congenital heart defects, showing that SLC25A1 regulates trophoblast differentiation and placental development to safeguard embryonic heart formation. 🐭🫀 https://bit.ly/4g372OU #DevBio
27.11.2024 14:38 — 👍 24 🔁 4 💬 1 📌 1
