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Joe Peters Lab

@joepeterslab.bsky.social

Professor and Chair, Dept Microbiology Cornell Ithaca. Interested in genome evolution and mobile DNA, especially Tn7 and CRISPR-Cas transposition systems

1,268 Followers  |  718 Following  |  80 Posts  |  Joined: 27.09.2023  |  2.2644

Latest posts by joepeterslab.bsky.social on Bluesky

Microbiology

In addition to a highly collaborative lab environment we interact with a dynamic Microbiology community, DNA Replication, Recombination and Repair group and a growing list of transposon-centered lab cals.cornell.edu/microbiology cals.cornell.edu/microbiology...

05.10.2025 14:55 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Technician III - Department of Microbiology Position Summary This position will be in the lab of Dr. Joseph E. Peters in the Department of Microbiology. Research in the Peters’ lab broadly involves deciphering mechanisms in genome stability and...

The Peters lab is looking for a new team member! The role transposons play in evolution, basic mechanisms regulating transposition, and applying transposons as tools for genome modification with a special focus on guide RNA-directed transposition. cornell.wd1.myworkdayjobs.com/CornellCaree...

03.10.2025 13:01 β€” πŸ‘ 26    πŸ” 21    πŸ’¬ 2    πŸ“Œ 0
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De novo engineered guide RNA-directed transposition with TnpB-family proteins reveals features of naturally evolved systems Programmable DNA integration using CRISPR-associated transposons (CASTs) offers powerful capabilities for genome engineering. The single effector Cas12k CAST examples evolved from a fixed guide TnpB n...

De novo engineered guide RNA-directed transposition with TnpB-family proteins reveals features of naturally evolved systems www.biorxiv.org/content/10.1...

28.08.2025 12:23 β€” πŸ‘ 23    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0

The RecBCD complex interacts directly with the DNA sliding clamp in Escherichia coli https://www.biorxiv.org/content/10.1101/2025.08.20.671105v1

21.08.2025 04:16 β€” πŸ‘ 7    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Mike Petassi presenting a slide

Mike Petassi presenting a slide

Mike Petassi eating lunch with the Joe Peters lab

Mike Petassi eating lunch with the Joe Peters lab

Great to have former lab member Mike Petassi for a seminar with our Replication, Recombination, and Repair group! Presenting some of his postdoc work in the @dnacurtain.bsky.social lab. cals.cornell.edu/microbiology...

11.08.2025 19:02 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Looking forward to this new installment of the Woods Hole Mobile DNA Meeting! Fantastic program, laid-back atmosphere, and gorgeous setting at the Marine Biological Laboratory ⛡️πŸͺΌπŸ‹
Abstract submission closes Aug 7 but registration after that date is possible. www.eventsquid.com/event.cfm?ev...

05.08.2025 20:47 β€” πŸ‘ 23    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0

Tn7 family transposons that include all of the guide RNA-directed transposons (CAST) are common in bacteria. We now find diverse representatives across archaea, with many in the Asgard group. Reviving an Asgard element confirmed the exciting behaviors of the family #MicroSky #TESky

30.07.2025 20:31 β€” πŸ‘ 22    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

Very excited about our work from @jordanthesier.bsky.social and @popomicro.bsky.social et al. We find that Tn7 family elements common in bacteria (that include all of the guide RNA-directed transposons, CAST) are also found across archaea including many in the exciting Asgard group! #MicroSky #TESky

30.07.2025 20:27 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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The mobile genome: genetic and physiological impacts of transposable elements

The mobile genome: genetic and physiological impacts of transposable elements www.embl.org/about/info/c...

29.07.2025 13:02 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Today is the last day to submit to be considered for a podium presentation at the EMBO transposon meeting this Fall. The organizers prioritized speaker slots sourced from submitted abstracts, we want to hear about your science!

29.07.2025 12:59 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Microbial metal physiology: ions to ecosystems Nature Reviews Microbiology - Metal ions are required for all cells, and their homeostasis relies on ancient mechanisms that facilitate their import, distribution and storage. In this Review,...

Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field.
#MicroSky #Metals

rdcu.be/eycU2

28.07.2025 17:08 β€” πŸ‘ 98    πŸ” 41    πŸ’¬ 4    πŸ“Œ 1

We're hiring! Do you have experience engineering yeast and using CRISPR? Jose Avalos and I are hiring a joint postdoc to work on an exciting fast-paced DARPA project with a great team at Neochromosome, Fermeate, and @joepeterslab.bsky.social

puwebp.princeton.edu/AcadHire/app...

17.06.2025 15:01 β€” πŸ‘ 3    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
About Barbara McClintock – Barbara McClintock Life Sciences Lecture Series

McClintock did her undergraduate and graduate studies at Cornell and we continue to be inspired by her groundbreaking work. We also have a lecture series and dormatory named in her honor at Cornell. mcclintock-lecture-series.research.cornell.edu/about-barbar...

16.06.2025 16:01 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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The mobile genome: genetic and physiological impacts of transposable elements

A great day to consider a submission to #MobileDNAjournal or attending a fantastic EMBO meeting on the topic this Fall www.embl.org/about/info/c...

16.06.2025 15:56 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Happy Transposon Day! 🧬➰🧬 Commemorating Barbara McClintock's birthday (June 16th, 1902-1992). #TransposonDay2025

16.06.2025 15:53 β€” πŸ‘ 19    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0

Linking to #microsky #transposon

15.06.2025 11:51 β€” πŸ‘ 7    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Exciting work from the GuarnΓ© lab indicating how the elusive TnsE pathway of prototypic Tn7 recognizes DNA replication features using an asymmetric dimer to integrate multiple signals at DNA replication forks linking target recognition to transposase recruitment doi.org/10.1093/nar/...

15.06.2025 11:43 β€” πŸ‘ 12    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1
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First podcast recording of the day. Guest is Dr. Tory Hendry of Cornell University, chatting about interactions between fluorescent Pseudomonas and aphids!

23.05.2025 00:42 β€” πŸ‘ 19    πŸ” 6    πŸ’¬ 0    πŸ“Œ 1

𝘒𝘧π˜ͺ𝘀π˜ͺ𝘰𝘯𝘒π˜₯𝘒𝘴 & 𝘒𝘧π˜ͺ𝘯𝘰𝘯𝘒π˜₯𝘰𝘴 of chromosome ends (bacterial!) take note πŸ‘‡
#MicroSky

29.03.2025 16:43 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Selected Publications S-C Hsieh, M FΓΌlΓΆp, R. Schargel, MT Petassi, O Barabas, and JE Peters (2025) Telomeric transposons are pervasive in linear bacterial genomes. Science 387:6741(Free-access, reprint link)L Chacon Machad...

Note: there is a free-access reprint-link on the Peters lab publications page cals.cornell.edu/microbiology...

28.03.2025 17:19 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Selected Publications S-C Hsieh, M FΓΌlΓΆp, R. Schargel, MT Petassi, O Barabas, and JE Peters (2025) Telomeric transposons are pervasive in linear bacterial genomes. Science 387:6741(Free-access, reprint link)L Chacon Machad...

Note: there is a free-access reprint-link on the Peters lab publications page cals.cornell.edu/microbiology...

28.03.2025 17:18 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Telomeric transposons are pervasive in linear bacterial genomes Eukaryotes have linear DNA, and their telomeres are hotspots for transposons, which in some cases took over telomere maintenance. We identified several families of independently evolved telomeric tran...

wow, telomeric transposons in bacteria with linear chromosomes! (of course this was first figured out in flies, inc by Bob Levis, who i was happy to see few days ago at the fly meeting). πŸͺ°

www.science.org/doi/10.1126/...

www.sciencedirect.com/science/arti...

www.sciencedirect.com/science/arti...

27.03.2025 20:55 β€” πŸ‘ 62    πŸ” 36    πŸ’¬ 0    πŸ“Œ 1

A thread from the Postdoc who led the work on bacterial Telomeric transposons. A wonderful collaboration with the Barabas lab. Officially out in the journal today!

27.03.2025 19:55 β€” πŸ‘ 15    πŸ” 2    πŸ’¬ 1    πŸ“Œ 1
Selected Publications S-C Hsieh, M FΓΌlΓΆp, R. Schargel, MT Petassi, O Barabas, and JE Peters (2025) Telomeric transposons are pervasive in linear bacterial genomes. Science Online First Release (Free-access, reprint link)L ...

Note: there is a free-access reprint-link on our lab publications page cals.cornell.edu/microbiology...

08.03.2025 15:34 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Selected Publications S-C Hsieh, M FΓΌlΓΆp, R. Schargel, MT Petassi, O Barabas, and JE Peters (2025) Telomeric transposons are pervasive in linear bacterial genomes. Science Online First Release (Free-access, reprint link)L ...

Note: there is a free-access reprint-link on our lab publications page cals.cornell.edu/microbiology...

08.03.2025 15:33 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Did you know that two jumping sequences (LINE-1 and Alu) make up nearly 30% of our genomes? Ever wonder how they jump into new genomic sites? We have some exciting discoveries to share new in @science.org on the structural mechanisms of LINE-1 retrotransposition (aka jumping 🧬➑️🧬) πŸ§ͺ #ScienceResearch

07.03.2025 00:22 β€” πŸ‘ 111    πŸ” 43    πŸ’¬ 6    πŸ“Œ 5
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Telomeric transposons are pervasive in linear bacterial genomes Eukaryotes have linear DNA and their telomeres are hotspots for transposons, which in some cases took over telomere maintenance. Here we identify several families of independently evolved telomeric tr...

Telomeric transposons are pervasive in linear bacterial genomes | Science www.science.org/doi/10.1126/...

06.03.2025 20:02 β€” πŸ‘ 143    πŸ” 75    πŸ’¬ 6    πŸ“Œ 5

Our preprint is now published www.science.org/doi/10.1126/...

06.03.2025 19:47 β€” πŸ‘ 38    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1

Proud to study transposons at Cornell where she did her undergraduate and graduate degrees

06.03.2025 19:38 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Very excited about this work from graduate student Laura Chacon Machado now published in Mobile DNA, "A family of Tn7-like transposons evolved to target CRISPR repeats"! #TESky

18.02.2025 22:05 β€” πŸ‘ 14    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

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