Tn7 family transposons that include all of the guide RNA-directed transposons (CAST) are common in bacteria. We now find diverse representatives across archaea, with many in the Asgard group. Reviving an Asgard element confirmed the exciting behaviors of the family #MicroSky #TESky
30.07.2025 20:31 β π 21 π 10 π¬ 0 π 0
Very excited about our work from @jordanthesier.bsky.social and @popomicro.bsky.social et al. We find that Tn7 family elements common in bacteria (that include all of the guide RNA-directed transposons, CAST) are also found across archaea including many in the exciting Asgard group! #MicroSky #TESky
30.07.2025 20:27 β π 10 π 3 π¬ 0 π 0
The mobile genome: genetic and physiological impacts of transposable elements
The mobile genome: genetic and physiological impacts of transposable elements www.embl.org/about/info/c...
29.07.2025 13:02 β π 0 π 0 π¬ 0 π 0
Today is the last day to submit to be considered for a podium presentation at the EMBO transposon meeting this Fall. The organizers prioritized speaker slots sourced from submitted abstracts, we want to hear about your science!
29.07.2025 12:59 β π 3 π 2 π¬ 1 π 0
Microbial metal physiology: ions to ecosystems
Nature Reviews Microbiology - Metal ions are required for all cells, and their homeostasis relies on ancient mechanisms that facilitate their import, distribution and storage. In this Review,...
Metal ions are universally required for life, and many of the foundational principles of metal homeostasis have emerged from studies of microbial systems. In this review, I provide a introductory overview targeted to those new to the field.
#MicroSky #Metals
rdcu.be/eycU2
28.07.2025 17:08 β π 96 π 41 π¬ 4 π 1
We're hiring! Do you have experience engineering yeast and using CRISPR? Jose Avalos and I are hiring a joint postdoc to work on an exciting fast-paced DARPA project with a great team at Neochromosome, Fermeate, and @joepeterslab.bsky.social
puwebp.princeton.edu/AcadHire/app...
17.06.2025 15:01 β π 3 π 4 π¬ 0 π 0
About Barbara McClintock β Barbara McClintock Life Sciences Lecture Series
McClintock did her undergraduate and graduate studies at Cornell and we continue to be inspired by her groundbreaking work. We also have a lecture series and dormatory named in her honor at Cornell. mcclintock-lecture-series.research.cornell.edu/about-barbar...
16.06.2025 16:01 β π 3 π 0 π¬ 0 π 0
The mobile genome: genetic and physiological impacts of transposable elements
A great day to consider a submission to #MobileDNAjournal or attending a fantastic EMBO meeting on the topic this Fall www.embl.org/about/info/c...
16.06.2025 15:56 β π 2 π 1 π¬ 0 π 0
Happy Transposon Day! π§¬β°π§¬ Commemorating Barbara McClintock's birthday (June 16th, 1902-1992). #TransposonDay2025
16.06.2025 15:53 β π 19 π 6 π¬ 2 π 0
Linking to #microsky #transposon
15.06.2025 11:51 β π 7 π 2 π¬ 0 π 0
Exciting work from the GuarnΓ© lab indicating how the elusive TnsE pathway of prototypic Tn7 recognizes DNA replication features using an asymmetric dimer to integrate multiple signals at DNA replication forks linking target recognition to transposase recruitment doi.org/10.1093/nar/...
15.06.2025 11:43 β π 11 π 5 π¬ 0 π 1
First podcast recording of the day. Guest is Dr. Tory Hendry of Cornell University, chatting about interactions between fluorescent Pseudomonas and aphids!
23.05.2025 00:42 β π 19 π 6 π¬ 0 π 1
π’π§πͺπ€πͺπ°π―π’π₯π’π΄ & π’π§πͺπ―π°π―π’π₯π°π΄ of chromosome ends (bacterial!) take note π
#MicroSky
29.03.2025 16:43 β π 8 π 1 π¬ 1 π 0
Telomeric transposons are pervasive in linear bacterial genomes
Eukaryotes have linear DNA, and their telomeres are hotspots for transposons, which in some cases took over telomere maintenance. We identified several families of independently evolved telomeric tran...
wow, telomeric transposons in bacteria with linear chromosomes! (of course this was first figured out in flies, inc by Bob Levis, who i was happy to see few days ago at the fly meeting). πͺ°
www.science.org/doi/10.1126/...
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...
27.03.2025 20:55 β π 62 π 36 π¬ 0 π 1
A thread from the Postdoc who led the work on bacterial Telomeric transposons. A wonderful collaboration with the Barabas lab. Officially out in the journal today!
27.03.2025 19:55 β π 15 π 2 π¬ 1 π 1
Did you know that two jumping sequences (LINE-1 and Alu) make up nearly 30% of our genomes? Ever wonder how they jump into new genomic sites? We have some exciting discoveries to share new in @science.org on the structural mechanisms of LINE-1 retrotransposition (aka jumping π§¬β‘οΈπ§¬) π§ͺ #ScienceResearch
07.03.2025 00:22 β π 111 π 43 π¬ 6 π 5
Our preprint is now published www.science.org/doi/10.1126/...
06.03.2025 19:47 β π 38 π 8 π¬ 1 π 1
Proud to study transposons at Cornell where she did her undergraduate and graduate degrees
06.03.2025 19:38 β π 1 π 0 π¬ 1 π 0
Very excited about this work from graduate student Laura Chacon Machado now published in Mobile DNA, "A family of Tn7-like transposons evolved to target CRISPR repeats"! #TESky
18.02.2025 22:05 β π 14 π 6 π¬ 0 π 0
A painting of Louis Pasteur with germs in the background, and a flask in the foreground showing him climbing a glacier.
AIR-BORNE EXCERPT! Louis Pasteur climbed a glacier to hunt for floating germs. There he discovered a fundamental truth about all life. Here's the story, from my new book. [Gift link] Artwork by Antoine Maillard. π§ͺ 1/2 www.nytimes.com/2025/02/17/s...
17.02.2025 15:20 β π 145 π 36 π¬ 6 π 7
I had the great pleasure of interacting with Bik Tye and her lab for many years at Cornell where she was one of the founding members of our DNA Replication, Recombination, and Repair (R3) group. It was wonderful to see this profile in PNAS www.pnas.org/doi/10.1073/...
17.02.2025 14:27 β π 5 π 0 π¬ 0 π 0
Want to learn more about genetic tools for studying bacteria and phage, check out the summer ABG Course at CSHL. This will be the 80th anniversary of the original CSHL Phage course, so you'll also meet many additional visiting genetics gurus! <https://meetings.cshl.edu/courses.aspx?course=C-ABG>
29.01.2025 03:53 β π 26 π 20 π¬ 1 π 1
Agree, but in fairness sometimes itβs a transposon defense system
19.01.2025 13:10 β π 3 π 0 π¬ 0 π 0
If there's something we don't understand I assume transposons are responsible unless proven otherwise
18.01.2025 18:23 β π 130 π 29 π¬ 16 π 4
Aka DanDan in the Peters Lab
Computational microbiologist. Senior scientist at @cemess.bsky.social, @univie.ac.at.
Microbial ecology, mostly of nitrogen cycle microbes, and data driven physiology.
Maintainer of the GlobDB genome database https://globdb.org
PhD Candidate in the Fineran Lab - studying the type I-D CRISPR-Cas system π¦ π©πΌβπ¬
πUniversity of Otago, Dunedin, NZ π³πΏ
James Davies Lab, Oxford University
Pro-prokaryote and phage phan, PhDoing at University of Copenhagen @microUCPH. MGEs, CRISPR, defense systems. RT=Reverse Transcriptase
Postdoctoral researcher - Institut Pasteur - Team "Bacterial Genome Plasticity" - Mazel's Lab -Molecular microbiology - HGT - MGE - DNA recombination.
Predoctoral researcher at evodynamics lab in Madrid.
Bacterial and plasmid evolution π«§π§¬π»
Asst. Prof. in Civil and Environmental Engineering & the Omenn-Darling Bioengineering Institute at Princeton
Programming living electronic materials and microbial communities for sustainability #FirstGen
atkinson.lab.princeton.edu
Researcher at National Research Council Canada
Microbial pathogenesis
Bioinformatician @ EMBL-EBI - Ensembl Genebuild
Formerly:
Post Doctoral Researcher @ UCC, Ireland
RNA Biology, Translation, Ribo-Seq
Bioinformatic Method Development & Research Infrastructure
A multidisciplinary community of researchers with the mission to better understand the roots of disease and narrow the gap between new biological insights and impact for patients. Broadinstitute.org
A new scientific institution for curiosity-driven biomedical science and technology.
Doudna Lab at UC Berkeley, Innovative Genomics Institute founder, CRISPR co-inventor and Nobel laureate innovativegenomics.org/
Assistant Professor @Biozentrum, University of Basel.
Jumbophage, Bacterial Immunity, Evolution
Everything phage biology and bacterial immunity
Assistant professor at Skoltech, Russia
CRISPRologist @ UMass Chan Medical School, RNA Therapeutics Institute. Player for Team Hope, Team Reality, and Team Cat. RNA rules.
Vibrio, quorum sensing, phage defense, and interbacterial interactions.
https://gsbs.tufts.edu/faculty-research/wai-leung-ng-lab
Assistant Professor at UCIrvine. Biochemistry and structural biology enthusiast. Dabbling in innate immunity and microbiology. Phage defense, cyclic nucleotides, and cool enzymes. (he/him/his) https://faculty.sites.uci.edu/morehouselab/
microbiologist studying bacterial-phage interactions. mom of two. Assistant prof @WUSM_MolMicro. http://leroux-lab.org. #newPI. Views are my own.
