Thomas Agoritsas

Responding to public health challenges of medical advice from social media influencers Raffael Heiss and colleagues argue that influencers’ medical advice is often shaped by multiple biases and suggest how to reduce the associated risks Social media influencers have become powerful in ...

Challenges with medical advice from social media influencers www.bmj.com/content/391/...

Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health.

Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health.

Part of a Lancet Infographic summarising the findings from the Lancet Series on Ultra-Processed Foods and Human Health.

Ultra-processed foods – what’s the impact?

In a new Lancet Series, experts warn a global rise in #UPFs presents a growing public health threat.

Read the evidence & policy recommendations ⬇️
spkl.io/63327AduhR

Can we individualize the 'number needed to treat'? An empirical study of summary effect measures in meta-analyses - PubMed The fixed effects OR, random effects OR and random effects RR appear to be reasonably constant across different baseline risks. Given the interpretational and arithmetic ease of RR, clinicians may wis...

Are #RelativeRisks overwhelmingly similar across risk groups? And if so, can we personalize care by applying relative risk to individual patients’ risk profiles? This key #EBM study demonstrates that the answer to both questions is an unquestionable YES.
pubmed.ncbi.nlm.nih.gov/11914297/

Shared decision-making as a method of care Care happens in interaction between the patient and the clinician, in conversation where the patient and clinician uncover or develop a shared understanding of the problematic situation of the patient...

Forming #EvidenceBased plans of #EBM care that respond to each patient’s situation demands #SharedDecisionMaking. JP Brito, Iris Hargraves, and Marleen Kunneman are doing leading work to advance the practice of making care fit using shared decision making.

ebm.bmj.com/content/28/4...

🚨⚕️Enhancing clinical encounters: our new systematic review on how hospitals’ institutional programs could protect or increase the time dedicated to interactions.
It included 117 unique studies comprising 298,517 patients 👇

link.springer.com/article/10.1...

Interdisons les « thérapies de conversion » dans l’UE ! L’UE examine l’Initiative citoyenne européenne (ICE) visant à interdire les “thérapies de conversion” dans toute l’Europe. Les prochains mois seront décisifs : agiront-ils vraiment ou détourneront-ils...

L'UE examine l'Initiative citoyenne européenne (ICE) visant à interdire les "thérapies de conversion" dans toute l'Europe. Les prochains mois sont essentiels – assurons-nous qu'elle agisse. J'ai signé. Rejoignez-moi 👉 a.allout.org/s/OJyE5/

They founded MAGIC over ten years ago to improve how evidence is generated, translated, and used in clinical decisions. The goal was clear: more transparency, more trust, better patient care. Inspiring to see what it has become.
📸: Per Vandvik & @thomasagoritsas.bsky.social

15 minute #JAMA podcast in which I interview world authority @thomasagoritsas.bsky.social on how to Use a Patient Management #Recommendations: #ClinicalPracticeGuidelines and #DecisionAnalyses

edhub.ama-assn.org/jn-learning/...

A #MAGICal conversation between @guyattgh.bsky.social , MAGIC's lead methodologist, and @thomasagoritsas.bsky.social , MAGIC's Board Chair, featured in JAMA Network learning podcast 💥 on #CPG and decision analyses

Don't miss that out!
edhub.ama-assn.org/jn-learning/...

At MAGIC, transformation doesn’t come from a single innovation — it comes from innovation + connection.

🔹 MAGICapp: digital infrastructure for living guidance
🔹 Turning evidence into action
🔹 Making sure guidance is used, not just published

📅 See MAGICapp in action → wkf.ms/3W17lBN

Are you developing clinical practice guidelines?

At MAGIC, we’re building tools and collaborations to make evidence-based guidelines more trustworthy and dynamic.

If your team is working on guidelines, we invite you to get to know MAGIC & MAGICapp
Get in touch:
forms.monday.com/forms/baaf06...

At MAGIC, we turn the best evidence into trustworthy guidance to improve patient care.

💡 #MAGICapp powers this process — a digital platform to build, publish, and update clinical practice #guidelines.

😎 Backed by a global network of leading methodologists.

magicevidence.org

Still using Word and PDFs for guidelines 💥 ? In 2025, there’s a better way 🤩
#MAGICapp helps teams move from clunky documents to structured, collaborative guidelines:

Curious if it’s right for you?
👉 Book a demo to learn more: forms.monday.com/forms/baaf06...

Over 3 billon people live with neurological disorders

1 in 3 people is living with neurological condition, such as stroke, epilepsy, migraine, autism.

Despite the number of people with these conditions, those in low- and middle- income countries face the greatest challenges http://bit.ly/4oj81yH

🚨⚕️Enhancing clinical encounters: our new systematic review on how hospitals’ institutional programs could protect or increase the time dedicated to interactions.
It included 117 unique studies comprising 298,517 patients 👇

link.springer.com/article/10.1...

Congratulations ! Is it available online ?

Image showing people clearing a bomb site in Gaza

"Moving beyond the uncomfortable apathy of medical neutrality is the duty of professionals and their organisations."

Where genocide, healthocide, and atrocities start, medical neutrality ends, says @kamranabbasi.bsky.social in this Editor's Choice
www.bmj.com/content/391/...

Testimony, advocacy, and the public health effect of genocide Medical community must play its part in ending atrocities In 2000, JAMA published a commentary by Willis and Levy calling for action to ensure recognition of the public health impact of genocide.1 Th...

“One factor is denial. Those responsible for genocide do not admit to their plans. Allies support their denials. Declassified documents show that US, French, and Belgian officials knew that genocide was occurring in Rwanda and avoided taking action” @bmj.com www.bmj.com/content/391/...

A must-read. So much in there about what matters, and how to preserve it. 🙏

The Un-Mattering of People: The Present and Near-Future of Surveillance Capitalism and the Fate of Care in Healthcare The encroachment of surveillance capitalism into healthcare takes place as healthcare becomes increasingly industrialized.

A great discussion paper by Montori et al. for @harvard-carr-ryan.bsky.social.

They warn that surveillance capitalism is reshaping healthcare into a system focused on data rather than people, enabling Big Tech to commodify human experience and consolidate power:

www.hks.harvard.edu/centers/carr...

Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis - International Journal of Obesity International Journal of Obesity - Effects of tirzepatide on weight management in patients with and without diabetes: a systematic review and meta-analysis

More than 2 decades since GLP-1 drugs were introduced, we still don't know why people with diabetes lose about half as much weight as those without diabetes at the same dose
nature.com/articles/s41...

The richest man on earth owns X.

The second richest man on earth is about to be a major owner of TikTok.

The third richest man owns Facebook, Instagram, and WhatsApp.

The fourth richest man owns The Washington Post.

See the problem here?

We Are Losing the Information War with Ourselves If the medium is the message, the message is mass psychosis.

“Loosing the information war?
- Get off social media
- Read good books & real journalism
- Find your friends
- And enjoy your life.”
samharris.substack.com/p/we-are-los...

5 problems in guideline development — solved with #MAGICapp 😎
✅ Simpler workflow
✅ Real-time collaboration
✅ Always up to date

🔗 Book a demo: forms.monday.com/forms/baaf06...
@thomasagoritsas.bsky.social @chrischampion.bsky.social

There are no sides.

How effective are de-implementation strategies to reduce low value care? Aleksi Raudasoja and colleagues conducted a systematic review and meta analysis to find out. 🧵

Is that so? Sounds nonsensical and rude (particularly when added to a post celebrating a friendship). Good day to you.

Distinguishing the Difference Between Curing and Caring When Treating Patients Dr. Victor Montori, MD, MSc, Robert H. and Susan M. Rewoldt Professor of Medicine and leader of the Knowledge and Evaluation Research (KER) Unit at the Mayo Clinic and Co-Founder of The Patient Rev...

Distinguishing the Difference Between Curing and Caring When Treating Patients | NEJM Catalyst catalyst.nejm.org/doi/full/10.... @patientrevolution.org

Strategic meetings beteeen MAGIC and WHO to support their clinical practice guidelines
@magicevidence.bsky.social @chrischampion.bsky.social

Operationalizing trustworthy #AI for #GRADE:
JUDGE turns tacit rating-down into 25 teachable prompts.
SMART-GRADE uses #LLMs + human-in-the-loop for traceable summaries.
Next: expand use cases + benchmarks with guideline panels. #GIN2025
@thomasagoritsas.bsky.social @guyattgh.bsky.social