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Josien

@joscience.bsky.social

#astrocytes fanatic. Studying the stars of the brain in sensory processing. Also SciCom, books, music and running.

691 Followers  |  754 Following  |  101 Posts  |  Joined: 15.11.2024  |  2.0003

Latest posts by joscience.bsky.social on Bluesky

Same in France! To rent an apartment you need a proof of 3 rent payments in France or you need a (French) guarantee. So what if you never lived in France? Also, to open a bank account you need a French phone number, but to get phone subscription you need a French bank account๐Ÿคฆโ€โ™€๏ธ. Catch22!

10.10.2025 12:28 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Problemen rond wetenschappelijke integriteit halen zelden de media. Dinsdag vertel ik waarom dat problematisch is voor het publieke vertrouwen in de wetenschap en de media, bij een colloquium van @isis-radboud.bsky.social, @willemhalffman.bsky.social. Ook @elisabethbik.bsky.social is van de partij!

09.10.2025 09:17 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Als de woorden worst en burger al zo verwarrend zijn voor de mensen, waarom maakt de Europese Unie zich dan niet druk over partijen die vrijheid of democratie ten onrechte in hun naam hebben staan?

08.10.2025 13:46 โ€” ๐Ÿ‘ 861    ๐Ÿ” 259    ๐Ÿ’ฌ 48    ๐Ÿ“Œ 13
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Wildlife advocate, primate expert Jane Goodall dies at 91 Scientist and global activist Jane Goodall, who turned her childhood love of primates into a lifelong quest for protecting the environment, died on Wednesday at the age of 91, the institute she founded said.

โ€œIt actually doesnโ€™t take much to be considered a difficult woman. Thatโ€™s why there are so many of us.โ€
www.reuters.com/business/env...

02.10.2025 05:39 โ€” ๐Ÿ‘ 1    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing - Nature Neuroscience The authors develop a new computational system for high-throughput mapping of synaptic connectivity using two-photon holographic optogenetics and intracellular recordings.

A pair of papers on using holographic optogenetics and compressed sensing for connectomics:

Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

www.nature.com/articles/s41...

19.09.2025 04:15 โ€” ๐Ÿ‘ 31    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
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How does air pollution impact your brain? - Neurofrontiers Air pollution is increasingly recognized as having negative effects on brain health. Here we take a look at what those are.

Weโ€™ve known for some time that air #pollution is bad for human #health. But the focus was mostly on the lungs and heart. Yet somewhere along the way, it became more mainstream to consider how air pollution might affects brains too. What I found surprising was the recency of that.
#neuroskyence

14.09.2025 18:25 โ€” ๐Ÿ‘ 29    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Thrilled to share that our work is now published in Science! โœจ

We found a preference for visual objects in the mouse spatial navigation system where they dynamically refine head-direction coding. In short, objects boost our inner compass! ๐Ÿงญ

www.science.org/doi/10.1126/...

๐Ÿงต1/

11.09.2025 20:12 โ€” ๐Ÿ‘ 170    ๐Ÿ” 71    ๐Ÿ’ฌ 8    ๐Ÿ“Œ 6
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Bottom trawling to continue in English protected waters, government rules Defra says blanket ban on โ€˜destructiveโ€™ fishing practice disproportionate as MPs urge minister to reconsider

This is infuriating. What is the point of a Marine Protected Area if trawlers are allowed to keep ploughing it?
Yet again, the government has succumbed to commercial lobbying.
www.theguardian.com/environment/...

09.09.2025 06:15 โ€” ๐Ÿ‘ 2441    ๐Ÿ” 993    ๐Ÿ’ฌ 90    ๐Ÿ“Œ 80
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Astrocyte networks span large swaths of brain The networks are plastic, connect brain regions that arenโ€™t connected by neurons and may enable long-distance communication between astrocytes, a new preprint shows.

www.thetransmitter.org/astrocytes/a...

03.09.2025 11:16 โ€” ๐Ÿ‘ 25    ๐Ÿ” 9    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

There is no reasonable justification not to ban bottom trawling everywhere.

28.08.2025 13:12 โ€” ๐Ÿ‘ 19    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks so much @dorsaamir.bsky.social and @chazfirestone.bsky.social, along with @mcxfrank.bsky.social, for your input on this! And ofc @sarahexplains.bsky.social and @parshallison.bsky.social for your editing!

22.08.2025 17:29 โ€” ๐Ÿ‘ 33    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Hereโ€™s the blunt reality โ€” reasonably-sized electric vehicles need to be the future of cars, but cars canโ€™t be the future of urban mobility.

Fewer cars.
Less driving.
More inviting mobility choices.
Better communities and cities.

These are the 4 pillars of the REAL urban transportation solution.

12.11.2024 15:31 โ€” ๐Ÿ‘ 715    ๐Ÿ” 197    ๐Ÿ’ฌ 16    ๐Ÿ“Œ 22
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Hippocampal representations drift in stable multisensory environments - Nature Tracking of individual place cells in mouse CA1 shows that representational drift is not influenced by changes in environment or behaviour, and is lower for more excitable place cells.

www.nature.com/articles/s41...

07.08.2025 19:53 โ€” ๐Ÿ‘ 31    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!

01.08.2025 01:56 โ€” ๐Ÿ‘ 22    ๐Ÿ” 10    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
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Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals - Nature Neuroscience The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that ...

Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals

www.nature.com/articles/s41...

31.07.2025 17:06 โ€” ๐Ÿ‘ 25    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Kicking off the lab BlueSky with this picture of a happy hairy growing #axon!
Looking forward to connecting with science chats and to growing research ideas ๐Ÿง ๐Ÿ”ฌโœจ

12.07.2025 10:05 โ€” ๐Ÿ‘ 64    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

Wow so pretty! Fascinating to see how these networks connect to distant regions specifically. You had a look into the specific functions of these connected regions?

23.07.2025 05:54 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...

22.07.2025 20:54 โ€” ๐Ÿ‘ 75    ๐Ÿ” 20    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 3
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My car got an Update #GLIA2025

21.07.2025 08:14 โ€” ๐Ÿ‘ 5    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

I previously noticed that to decode body movements from V1 superficial layers required much more neurons (>600) than my recordings of deep layers (~200). It's great to see a head-to-head comparison

19.07.2025 11:58 โ€” ๐Ÿ‘ 9    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Confocal microscopy photo of the cortex showing neurons and astrocytes

Confocal microscopy photo of the cortex showing neurons and astrocytes

Confocal microscopy photo of the cortex showing neurons and astrocytes

Confocal microscopy photo of the cortex showing neurons and astrocytes

Check out this cool astrocyte multitasking in the brain! It manages a blood vessel on one side while supporting a neuron on the other. Everything in the brain, from blood vessels to neurons, is interconnected! ๐Ÿ”ฌ ๐Ÿง 
#microscopy #Neuroscience

16.07.2025 17:26 โ€” ๐Ÿ‘ 122    ๐Ÿ” 20    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1
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What a week in Marseille! ๐Ÿ‡ซ๐Ÿ‡ท #GLIA2025 is done, but the buzz stays. Weโ€™re already gearing up for #GLIA2027! First step: forming the Programme Committee with a democratic vote by past delegates. Fun fact: GLIAโ€™s even in MarsiGLIA (Italian for Marseille)!
#GliologistsTogether

15.07.2025 09:27 โ€” ๐Ÿ‘ 8    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Screenshot of the top of the article, including the title, authors, and abstract.

Screenshot of the top of the article, including the title, authors, and abstract.

Whatโ€™s better than a one-channel #Miniscope? ๐Ÿฅ A TWO-CHANNEL Miniscope!

Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.

Read the paper here: www.science.org/doi/10.1126/...

(1/10)

14.07.2025 16:53 โ€” ๐Ÿ‘ 103    ๐Ÿ” 35    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 1

Amazing work! It's really interesting. Congratulations!

14.07.2025 10:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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A divergent astrocytic response to stress alters activity patterns via distinct mechanisms in male and female mice - Nature Communications Early-life stress has lifelong impacts on neuronal function and behavior. Here, the authors show that astrocytic glucocorticoid receptor signaling drives stress-induced neuronal and behavioral change ...

Absolutely thrilled to share the first half of my PhD work! Super proud to see it finally out!
www.nature.com/articles/s41...

Thread below for a quick (10 point) recap of what we found!
๐Ÿงต๐Ÿงช๐Ÿง 

11.07.2025 12:22 โ€” ๐Ÿ‘ 40    ๐Ÿ” 12    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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This Thursday at #GLIA2025 is packed with insights โ€” outstanding presentations and rich scientific content throughout the day. #Marseille

10.07.2025 13:51 โ€” ๐Ÿ‘ 14    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
An illustration of a mouse on a ball looking at a field of grass displayed on monitors.

An illustration of a mouse on a ball looking at a field of grass displayed on monitors.

Can your AI beat a mouse?

Mice still outperform our best computing machines in some ways. One way is robust visual processing.

10 years ago I decided to work on HARD behavior driven by COMPLEX visual processing. And that risk is paying off now. #neuroAI 1/n

10.07.2025 12:22 โ€” ๐Ÿ‘ 45    ๐Ÿ” 16    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
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Thanks to all the people who came to my poster! Lots of nice discussions and suggestions! #GLIA2025

08.07.2025 15:33 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Heading to #glia2025 in Marseille โ€” or as Italians call it, MarsiGLIA. Coincidence? I think not! ๐Ÿ˜Ž๐Ÿง 

07.07.2025 14:39 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Three-photon microscopy: an emerging technique for deep intravital brain imaging Nature Reviews Neuroscience - Optical microscopy allows neural cells to be studied in the intact brain, but imaging deep neural tissue presents substantial challenges. Prevedel and colleagues...

Excited to share our latest Review on three-photon microscopy in the neurosciences - out today in @natrevneuro.nature.com! Hopefully this will help spread this powerful deep-imaging technique even further.
Access here: rdcu.be/er5SZ
Thanks to all co-authors!

20.06.2025 13:51 โ€” ๐Ÿ‘ 30    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

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