Josien

Hippocampal representations drift in stable multisensory environments - Nature Tracking of individual place cells in mouse CA1 shows that representational drift is not influenced by changes in environment or behaviour, and is lower for more excitable place cells.

www.nature.com/articles/s41...

Thanks to @thetransmitter.bsky.social and @ldattaro.bsky.social for this coverage of our recent paper!

Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals - Nature Neuroscience The relative contribution of intrinsic and extrinsic factors to astrocyte heterogeneity is unknown. Using heterotropic transplantation of septal astrocytes with distinct lineage origins, we show that ...

Astrocyte specification in the mouse septum is shaped by both developmental origin and local signals

www.nature.com/articles/s41...

Kicking off the lab BlueSky with this picture of a happy hairy growing #axon!
Looking forward to connecting with science chats and to growing research ideas 🧠🔬✨

Wow so pretty! Fascinating to see how these networks connect to distant regions specifically. You had a look into the specific functions of these connected regions?

Now on bioRxiv! Astrocytes in one brain region (cyan) communicate in expansive networks (magenta). Through tool development, tissue clearing, and many hours on our @zeiss-microscopy.bsky.social Z1, we now know these networks are repeatable across mice, plastic, and specific.
doi.org/10.1101/2025...

My car got an Update #GLIA2025

I previously noticed that to decode body movements from V1 superficial layers required much more neurons (>600) than my recordings of deep layers (~200). It's great to see a head-to-head comparison

Confocal microscopy photo of the cortex showing neurons and astrocytes

Confocal microscopy photo of the cortex showing neurons and astrocytes

Check out this cool astrocyte multitasking in the brain! It manages a blood vessel on one side while supporting a neuron on the other. Everything in the brain, from blood vessels to neurons, is interconnected! 🔬 🧠
#microscopy #Neuroscience

What a week in Marseille! 🇫🇷 #GLIA2025 is done, but the buzz stays. We’re already gearing up for #GLIA2027! First step: forming the Programme Committee with a democratic vote by past delegates. Fun fact: GLIA’s even in MarsiGLIA (Italian for Marseille)!
#GliologistsTogether

Screenshot of the top of the article, including the title, authors, and abstract.

What’s better than a one-channel #Miniscope? 🥁 A TWO-CHANNEL Miniscope!

Our new Miniscope2C is a dual-channel, open-source Miniscope that lets you record 2 fluorescent signals simultaneously in freely moving animals.

Read the paper here: www.science.org/doi/10.1126/...

(1/10)

Amazing work! It's really interesting. Congratulations!

A divergent astrocytic response to stress alters activity patterns via distinct mechanisms in male and female mice - Nature Communications Early-life stress has lifelong impacts on neuronal function and behavior. Here, the authors show that astrocytic glucocorticoid receptor signaling drives stress-induced neuronal and behavioral change ...

Absolutely thrilled to share the first half of my PhD work! Super proud to see it finally out!
www.nature.com/articles/s41...

Thread below for a quick (10 point) recap of what we found!
🧵🧪🧠

This Thursday at #GLIA2025 is packed with insights — outstanding presentations and rich scientific content throughout the day. #Marseille

An illustration of a mouse on a ball looking at a field of grass displayed on monitors.

Can your AI beat a mouse?

Mice still outperform our best computing machines in some ways. One way is robust visual processing.

10 years ago I decided to work on HARD behavior driven by COMPLEX visual processing. And that risk is paying off now. #neuroAI 1/n

Thanks to all the people who came to my poster! Lots of nice discussions and suggestions! #GLIA2025

Heading to #glia2025 in Marseille — or as Italians call it, MarsiGLIA. Coincidence? I think not! 😎🧠

Three-photon microscopy: an emerging technique for deep intravital brain imaging Nature Reviews Neuroscience - Optical microscopy allows neural cells to be studied in the intact brain, but imaging deep neural tissue presents substantial challenges. Prevedel and colleagues...

Excited to share our latest Review on three-photon microscopy in the neurosciences - out today in @natrevneuro.nature.com! Hopefully this will help spread this powerful deep-imaging technique even further.
Access here: rdcu.be/er5SZ
Thanks to all co-authors!

Barcoded viral tracing identifies immunosuppressive astrocyte–glioma interactions - Nature Using viral barcode tracing to detect interactions between glioblastoma cells and non-malignant astrocytes in patient samples, investigators discovered a pathway that reduces tumour-specific immunity ...

Our newest paper studying immunosuppressive astrocyte-GBM interactions using RABID-seq is out in ‪@nature.com today! Congrats to Brian Andersen and Camilo Faust Akl!
www.nature.com/articles/s41...

So exciting (literally😉)! See you there!

Excited to share that I’m organizing a Special Trainee Symposium at Euroglia 2025 titled "Electrical dynamics in glia and their role in physiology and pathology"
Proud to contribute to a platform that highlights trainee-led science. Looking forward to vibrant discussions in Marseille!

Testing for trans-saccadic prediction error signaling by foveal SC neurons. Top: Monkeys generated a delayed, visually-guided saccade towards an extrafoveal target. The authors used a delayed paradigm to make sure that there was a stable visual image upon saccade generation. In some trials, the saccade target was unchanged throughout the whole trial (high spatial frequency grating embedded within a circular patch for this shown example). In other trials, they detected saccade onset and immediately flipped the saccade target to another feature (from a low to a high spatial frequency texture in the shown example). Bottom: The authors only selected foveal SC neurons with response fields (RF’s) not extending towards the pre-saccadic extrafoveal stimulus location. In this example, the RF was almost entirely contained within <2 deg eccentricity. Each black dot is a stimulus onset location during RF mapping, and the white circle (3 deg radius) shows the extent of the saccade target if it was perfectly foveated post-saccadically. The target covered the RF post-saccadically but not pre-saccadically. The z-axis indicates the visual response strength of the neuron at each stimulus location.

Why don't #saccades disrupt our continuous #visual experience? This study shows that neurons of the #SuperiorColliculus are sensitive to the pre-movement peripheral appearance of the eye movement targets, potentially explaining the experienced perceptual stability @plosbiology.org 🧪 plos.io/44cxQIe

‼️WORLD CLIMATIC HISTORY REWRITTEN
ALL NIGHT >40 DEGREES IN OMAN & EMIRATES
Dawn at 40C at Fujairah and Dhudna
Min 35.8 Rustaq,35.5 Sohar Majis:Hottest night ever

INSANITY IN PAKISTAN🇵🇰
MINIMUMS 34C 1200m and 30.6C at 1500m (Bunji)
WORLD RECORD HOT NIGHT AT THAT ELEVATION

Aahh that is why I did the same level twice! But It was the unit 75 review so more xp🤓

This is grim: 80% of participants that used LLM for writing struggled to "quote anything from their essays"

I wonder if this would be similar for math

My latest Aronov lab paper is now published @Nature!

When a chickadee looks at a distant location, the same place cells activate as if it were actually there 👁️

The hippocampus encodes where the bird is looking, AND what it expects to see next -- enabling spatial reasoning from afar

bit.ly/3HvWSum

Vacatures - PhD Cellular Neuroscience - Astrocyte Physiology - Amsterdam UMC Amsterdam Leukodystrophy Center is looking for a motivated PhD candidate to explore the fundamental physiology of astrocytes in the brain, in the context of brain fluid regulation.

🚨 PhD position in astrocyte physiology!

Join us in Amsterdam to explore how astrocytes dynamically regulate brain water flow!

Apply using the link below:
🧠🔬🌍

🔗 werkenbij.amsterdamumc.org/en/publicatie-1179368

#Neuroscience #PhD #Astrocytes #MLC #SUPERGLUE

What does chat know that we don't?

Neuroscience methods - YouTube Nanocourse: Approaches to Study Neural Circuits This course was taught by Anita Autry, Tiago Gonçalves, and Luke Sjulson at Albert Einstein College of Medici...

Announcing two new lectures in our youtube neuroscience methods course:

Lecture 12: experimental design (by Anita Autry)
Lecture 13: neuronal population coding (in which I advocate a viewpoint that is... controversial)

Please repost to help us spread the word!

www.youtube.com/playlist?lis...

Hey Zoe! I'm working on how we perceive the world around us using all our senses together. I look at the role of different brain cells. #neuroscience