Noor Pratap Singh's Avatar

Noor Pratap Singh

@noorpratap.bsky.social

CS PhD student at UMD. Interested in Computational Biology. Views driven by an unknown combination of previously consumed material (weights are dynamic). Previously at Genentech, IIIT-Hyderabad

69 Followers  |  128 Following  |  3 Posts  |  Joined: 21.11.2024  |  1.6632

Latest posts by noorpratap.bsky.social on Bluesky

🧬πŸ–₯️ oarfish v0.9.0 is out! The big improvement in this version is future-oriented. v0.9.0 allows the user to pass in transcript sequences via the `--annotated` option, the `--novel` option, or both. The provenance will be separately tracked to that later 1/4

29.06.2025 23:39 β€” πŸ‘ 17    πŸ” 6    πŸ’¬ 2    πŸ“Œ 0
Preview
Release v0.13.0 Β· COMBINE-lab/piscem Install piscem 0.13.0 Install prebuilt binaries via shell script curl --proto '=https' --tlsv1.2 -LsSf https://github.com/COMBINE-lab/piscem/releases/download/v0.13.0/piscem-installer.sh | sh Downl...

πŸ–₯️🧬 The new release (v0.13.0) of piscem is out. However, almost all changes here are transparent to the user (except for the need to rebuild the index before using the new version). I want to take a second to talk about something that often goes unappreciated. 1/x

github.com/COMBINE-lab/...

31.05.2025 19:16 β€” πŸ‘ 17    πŸ” 3    πŸ’¬ 1    πŸ“Œ 1
Preview
A simplified hybrid capture approach retains high specificity and enables PCR-free workflow Hybrid capture is a critical technology for selective enrichment of genomic regions of interest, enabling cost-effective focused sequencing in both clinical and research applications. We present a sim...

A preprint by @elembio.bsky.social on an on flowcell simplified hybrid capture approach that retains high specificity and enables PCR-free workflow www.biorxiv.org/content/10.1...

20.03.2025 08:54 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

@mikelove.bsky.social it's been a pleasure and an insightful experience collaborating with you. Thank you for taking out the time to attend my defense.

13.03.2025 21:45 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Excited and nervous at the time!!! Looking forward to it.

13.03.2025 03:05 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
Preview
Release v0.19.0 Β· COMBINE-lab/simpleaf Install simpleaf 0.19.0 Install prebuilt binaries via shell script curl --proto '=https' --tlsv1.2 -LsSf https://github.com/COMBINE-lab/simpleaf/releases/download/v0.19.0/simpleaf-installer.sh | sh...

We just released simpleaf v0.19.0 (github.com/COMBINE-lab/...). Make sure to pair it with piscem v0.12 for faster scATAC-seq processing. The other big feature & first explicit @scverse.bsky.social integration point is AnnData format output with the new `--anndata-out` flag!

25.01.2025 15:04 β€” πŸ‘ 11    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Preview
Movi: A fast and cache-efficient full-text pangenome index Biocomputational method; Classification of bioinformatical subject; Genomic analysis

Very excited to see Movi (by @mohsenzakeri.bsky.social) now out in iScience: www.cell.com/iscience/ful.... Movi builds on the "move structure" pangenome index, a compressed full-text index and close cousin to r-index. Compared to r-index, the move structure is simpler and more cache-efficient.

11.12.2024 16:48 β€” πŸ‘ 44    πŸ” 17    πŸ’¬ 1    πŸ“Œ 0

It should definitely be doable if we store the rank and then we can perhaps later use it in the augmented bed file. We currently do support a SAM file as an output for the mappings for all the reads in the fastqs but then that does not do any deduplication/barcode correction.

05.12.2024 05:45 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@noorpratap is following 20 prominent accounts