WachtenLab

The next #DGZ Focus Workshop on #Cilia & #Centrosomes will take place November 25 (end of October is our DGZ meeting in HD). Join us for a great speaker line-up, and big thanks to David Mick @mick-lab.bsky.social & Dagmar Wachten @wachtenlab.bsky.social for organizing!

Primary #cilia dysfunction as in Bardet-Biedl syndrome compromises normal adipogenic differentiation in favor of fibrogenic transition, predisposing to obesity
@wachtenlab.bsky.social and collaborators
www.embopress.org/doi/full/10....

BBS8-dependent ciliary Hedgehog signaling governs cell fate in the white adipose tissue | The EMBO Journal imageimageDisruption of ciliogenesis in Bardet-Biedl syndrome (BBS) leads to obesity and disrupted adipogenesis. This study reveals that ciliary dysfunction in a mouse model of BBS induces a a cell fa...

🚨 New in The EMBO Journal!
Loss of BBS8 disrupts ciliary Hedgehog signaling, switching adipocyte precursors into fibrogenic cells—remodeling adipose tissue before obesity begins.
🔬 #BBS #cilia @for5547.bsky.social @sfb1454.bsky.social @batenergy.bsky.social
📄 www.embopress.org/doi/full/10....

Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

🚨 Catching up with great news!
Our NAR paper with the @wachtenlab.bsky.social and supported by Prof. Möglich presents a powerful light-switch for gene expression in mammalian cells, with big potential for bioproduction and research.

#Optogenetics #SyntheticBiology #Bioproduction #GeneExpression

Potent optogenetic regulation of gene expression in mammalian cells for bioproduction and basic research Abstract. Precise temporal and spatial control of gene expression greatly benefits the study of specific cellular circuits and activities. Compared to chem

💡 Paper alert! We developed DEL-VPR, a potent blue-light photoswitch inducing gene expression in mammalian cells.
From basic research to antibody production, this tool offers precise & strong gene control. Teamwork with #Ningaloo
academic.oup.com/nar/article/...
#SyntheticBiology #Optogenetics

Kupffer cell programming by maternal obesity triggers fatty liver disease Nature - In a mouse model, maternal obesity during pregnancy can lead to fatty liver disease in the offspring, driven by aberrant developmental programming of Kuppfer cells.

We are SO EXCITED to share our story @nature.com:
🧵1/
Maternal obesity reprograms fetal liver macrophages, triggering adult fatty liver disease in the offspring.
This study uncovers how Kupffer cells act as intergenerational messengers in metabolic disease.
👉 Read here: rdcu.be/erD3b

Huge congratulations on the launch of your lab at UCSF! 🎉 Excited to see the amazing science to come on airway stem cells and multiciliated cell biology. Wishing the @choksilab all the best as you get started! 🧬💨 #NewLab #STEM

Looking forward to an inspiring 2-day #iii institute retreat packed with great science, collaborations, and fresh ideas. Grateful to @unibonn.bsky.social for hosting us in #IMPULSE! 🙌🔬

Huge congratulations! 🎉

Thrilled to be part of this amazing journey! 🙌 Hurray indeed! @dfg.de has just approved funding for ImmunoSensation3 🎉 Focused on Immune Diversity, we're set for 7 more years of cutting-edge #immunology in #Bonn! Let’s go! 💥 #ImmunoSensation #science

Proud PI - congratulations to Seniz for being awarded the "Rising Star" award of the @for5547.bsky.social #cilia

Grateful to be part of such a fantastic consortium! Huge thanks to our amazing coordinator Christina and to Silke for organizing an inspiring annual meeting in Jena. Latest new: we’ve got a new rising star on the team! #cilia

🎉 Huge congratulations to Susan Dutcher @dutcherlab.bsky.social on her election to the National Academy of Sciences! A well-deserved recognition of her outstanding contributions to cell biology and cilia research. 👏🔬 #WomenInSTEM #Cilia

We’ll miss you! Best of luck kicking off your own lab in Berlin — exciting times ahead!

Excited for an inspiring meeting in France 🇫🇷 on #cilia and #centrosomes! The German #cilia community is en route—let’s connect and share science!

Dear cilia researchers, join us in the heart of the beautiful Vosges mountains to share your latest findings! This year, partnership with @for5547.bsky.social and keynote lectures by @micromotility.bsky.social and @mick-lab.bsky.social
Registration is now open www.cfc2025.conferences-pasteur.org

Congratulations to Ronja from the @wachtenlab.bsky.social , who won the 1st poster prize at the international @batenergy.bsky.social meeting! 🎉🥳

Congratulations Kathrin and the whole team!!!

Congratulations and well deserved 🎉🥳

Cilia has been at the center of our discussions at the spring school of our @for5547.bsky.social cilia consortium.
In total there were 26 trainees from across Europe, few PIs and our brilliant coordinator Christina Klausen.

Interested in primary #cilia, #microtubules, #protein trafficking, molecular #signaling, #GPCRs, and #ciliopathies?

We are looking for a #postdoc and a #PhDstudent to apply advanced #biochemistry and #proteomics methods to study cilia.
Check out our website and send your application until March 10.

See you soon!

Thanks a lot to #FEBS and the Norwegian bioscience society for hosting me and special thanks to @nathaliejuya.bsky.social and @emreyaksi.bsky.social for your hospitality!

Looking forward to #Cilia 2027 - watch out for more information!

We would like to welcome you to our second International Conference on Brown and Beige Fat
March 31st - April 02nd 2025
Top-class speakers, cutting edge research and respected experts will come together in beautiful Bonn.
Registration is open!
www.trr333.uni-bonn.de/batenergy-sy...

This will open up proximity labeling to a broad cell biology community, allowing protein labeling in subcellular domains without background labeling. This is a major step forward to now do in vivo labeling using #iAPEX - congratulations to the whole team!

🗣️We are #hiring! Check out our the latest job opportunities!

▫️ Personnel Administration Expert
📌 Due date: 17/01/2025

▫️ Flow Cytometry Technician
📌 Due date: 19/01/2025

▫️ Postdoctoral Fellow in Innate Immune Biology (Dr. Stefanie Wculek)
📌 Due date: 28/02/2025

➡️ bit.ly/3MR4wO8

🧪

iAPEX: Improved APEX-based proximity labeling for subcellular proteomics using an enzymatic reaction cascade Ascorbate peroxidase (APEX) is a versatile labeling enzyme used for live-cell proteomics at high spatial and temporal resolution. However, toxicity of its substrate hydrogen peroxide and background la...

Fantastic team work by our @for5547.bsky.social PIs, headed by David Mick! Check this out: www.biorxiv.org/content/10.1...

Advert for the e-symposium with list of speaker, affiliations and imagegs of cilia and centrioles.

Line up of our speakers, affiliations and talk titles for our 50th event!

Calendars out- just over two weeks until our 🎉50th🥳 @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium 14/01/2025 15:00-17:30- everything hot in #cilia #centrosomes free & open to all! Register to access this 🔥 series: www.eventbrite.co.uk/e/bscb-genso... /1