Sara McHaffie

Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs - Nature Genetics Classes of autism are uncovered with a generative mixture modeling approach leveraging matched phenotypic and genetic data from a large cohort, revealing different genetic programs underlying their ph...

www.nature.com/articles/s41... A big, well funded team tries to sort autistic people into four invented categories, based on 7 other invented categories. Based e.g. on past research that doesn't say what they allege it says. No inclusion of autistic people, discussion of ethics, human rights, etc.

Absolutely! Knowing there will be recordings for a little while helps with the FoMo and let me take breaks and lie on the floor, so I'm travelling home still more or less able to human. Also the team on the welcome desk were so lovely!

Yep I didn't work this out until my 40s. All of the above. It's really sad to think about. Sometimes group dynamics as well as just one individual.

Help our show get traction so we can keep making it! You can do that by liking the video, commenting on it, sharing it with other autistic people / in your fave autism groups &, obv, watching it on a loop for the next fortnight!

Every little helps us get it in front of our audience 😻

I was sad not to make it in person today - hopefully one day we will be in the same place!

If I had more time I would have drawn out the links between your keynote and my findings - so much that resonated!

I'm reassured that I wasn't blasting through the slides so fast nobody could take anything in! Thank you

They work together as a good motto for life though

I'm thrilled that this paper is finally out - besjournals.onlinelibrary.wiley.com/doi/10.1002/.... I think it's my favourite piece of work so far, and I'm so thankful to my co-authors @saramch.bsky.social and @annastenning.bsky.social for the brilliant insights they contributed.

I need to know if they have steel toecaps. But would recommend a scooter without foot controls, if these boots were for some reason important.

This is one of those references in my literature analysis where I'm fairly sure anyone reading is going to look it up to see if I'm exaggerating.