Immune checkpoint TIM-3 regulates microglia and Alzheimerβs disease - Nature
The immune-checkpoint molecule TIM-3 regulates microglial homeostasis, and its microglial-specific deletion reduced cognitive impairment in a mouse model of Alzheimerβs disease.
With Butovsky Lab, we show that silencing TIM-3 in brain-resident immune cells prevents neurodegeneration in a mouse model of #Alzheimerβs disease. Deletion of TIM-3 in microglia enhance phagocytic clearance of toxic amyloid beta. #Immunoskyπ§ͺ www.nature.com/articles/s41...
09.04.2025 15:29 β π 38 π 14 π¬ 1 π 1
Day 1 - Advent of Code 2024
Advent Calendar for all!π
"Historian Hysteria" - Day 1 - Advent of Code 2024 #AdventOfCode adventofcode.com/2024/day/1
01.12.2024 10:15 β π 1 π 0 π¬ 0 π 0
NCI K00 Postdoc @ Jacks Lab at MIT
Yale 2022 | Holy Cross 2016
"You sort of start thinking anything's possible if you've got enough nerve."
Assistant Professor at the Department of Molecular Biology and Genetics at Cornell University
https://www.cellhomology.space/
Translational Immunology Research Lab at University of Minnesota Duluth.
Lab of Vijay Kuchroo at @GeneLayInstitute.bsky.social @BrighamAndWomens.bsky.social @HarvardMed.bsky.social @BroadInstitute.org
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Koch Center for Integrative Research at MIT. Cancer biology. Mouse models. Tumor immunology.
Research group leader @German Cancer Research Center, reconstructing human development and disease using cell fate engineering
Waitress turned Congresswoman for the Bronx and Queens. Grassroots elected, small-dollar supported. A better world is possible.
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Assistant Professor at @EPFL in Computer Science and Life Sciences. PostDoc at @Genentech and @Stanford. PhD at @ETH and @BroadInstitute.
www.aimm.epfl.ch
https://www.unimedizin-mainz.de/medizinische-mikrobiologie-und-hygiene/
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I study how mutations come about. Based at @columbiauniversity.bsky.social, previously at @normalesup.bsky.social
Max-Eder Research Group Leader & Physician Scientist @NCT/DKFZ @DKTK @Uniklinik_HD
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before PostDoc @Uchicago Gajewski lab
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oncodaily.com
Molecular Immunologist
TCRs, BCRs, and their ligands
Head of Immunology Discovery at BioMed X
Heidelberg, Germany and New Haven, CT
Based @LIMES Institute @University of Bonn, researching developmental immunology. We β€οΈ macrophages!
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