YouTube video by Dr. Glaucomflecken The Dangers of Raw Milk

youtube.com/shorts/CuSwN... I made some people big mad with this one

Really enjoyed this deep dive into intratumoural immune archetypes from Matt Krummel
#AACR25 @TheAACR.bsky.social

Loved this video on T Cell vs Dendritic Cell interacting

#IntratumouralHeterogeity
#ClonalEvolution
#ReactiveImmunity

Powerful insights into metastatic evolution and the importance of the microenvironment by Mariam Jamal-Hanjani

A brilliant plenary session on “Targeting the Cancer Ecosystem” - thanks to all four speakers and @marasherman.bsky.social for wonderful chairing 👏

#AACR2025
@theaacr.bsky.social

Excited to learn from this awesome panel at #AACR2025 as we talk about EO Cancers & their rising rates
As an early onset #colorectalcancer survivor & as someone who sees the impact of #EOCRC daily in #COLONTOWN, we need more concerted efforts to reduce the burden of EOCRC worldwide.
lnkd.in/drM7X2PS

Thrilled to participate in this hashtag#AACR2025 session on Regulatory Trends Shaping the Future of Cancer Drug Development and learn from these experts!
lnkd.in/d4WTshuY
See you there!

There are so many ways to rev up our immune response against cancer. Here, the oncolytic viruses
www.cell.com/cancer-cell/...

Need a dislike button for this!

Sorry to hear this.

the tens of thousands who suffer from the illness, especially in African nations where the disease is prevalent. You can read all this and more here:
• www.cbsnews.com/newyork/news...
• www.yahoo.com/news/long-is...
• www.nhlbi.nih.gov/health/sickl...
• www.fda.gov/news-events/...
• www.lyfgenia.com

is also looking to re-enroll in school to pursue a medical career, inspired by his own journey. Contributions have been made to Northwell Health, supporting the organization's continuing efforts in treating sickle cell disease, a move that signifies hope for the availability of the gene therapy for

had to stay in the hospital for about another month and said that January 13th was the day he felt like a new person as things kicked in. Beauzile says he’s not in pain anymore, and that he’s been able to do a lot of new things, including finally having the first chance for a carefree vacation. He

In late December, Sebastien’s stem cells were successfully re-infused back into him in a matter of minutes. Now he’s producing normal adult hemoglobin in his parent cells and that’s why he’s not having any symptoms related to his sickle cell disease according to his doctors. For assurances, Beauzile

Treatment Process STEP 1: LYGENIA is made specifically for you from your own blood stem cells. Your healthcare provider will collect your blood stem cells through a procedure/ process called mobilization and apheresis. This process takes approximately one week and may need to be repeated to obtain a sufficient number of cells. 'Back-up' stem cells (or 'rescue cells') are also collected and stored at the treatment center. This is a precaution in case there is a problem in the treatment process. If this happens, your back-up stem cells will be given back to you. If you receive back-up cells, you will have no benefit from LYFGENIA. STEP 2: Your blood stem cells will be sent to a manufacturing site where they are used to make your LYFGENIA. It typically takes 10 to 15 weeks from the time your cells are collected to make and test LYFGENIA before it is shipped to your healthcare provider, but the time may vary and be up to 22 weeks. STEP 3: Before you receive LYGENIA, your healthcare provider will give you chemotherapy for a few days to make room in the bone marrow. You will be admitted to the treatment center for this step and remain there until after LYGENIA infusion. STEP 4: LYFGENIA is given by an intravenous infusion. You may receive more than one bag of LYFGENIA. Each bag is infused in 30 minutes or less. After LYGENIA infusion, you will stay in the treatment center for approximately 3-6 weeks so that your healthcare team can closely monitor your recovery. Your healthcare provider will determine when you can go home.

treated with Lyfgenia in the lab before being infused back via a stem cell transplant. Before the procedure, the patient must undergo a round of high-dose chemotherapy to eliminate faulty blood stem cells and make room for new ones.

patient, and creates a new, healthy gene inserted into parent cells that connect to the stem cells of red blood cells afflicted by the illness instead of more painful procedures like bone marrow transplants. Patients’ own hematopoietic stem cells, or blood cell precursors, are collected and then

Figure 1. Basic Elements of the LYFGENIA Gene Therapy Process

treatment of sickle cell disease in patients 12 years of age and older with a history of vaso-occlusive events (VOEs). Lyfgenia delivers a modified version of the HBB gene that can produce a form of hemoglobin (HbAT87Q) that’s resistant to clumping or sickling. It is made SPECIFICALLY for each

was FDA approved in late 2023, Sebastien was the first patient on their minds, and it changed his life dramatically. Lyfgenia is a one-time gene therapy used to treat sickle cell disease in patients 12 years of age or older and a history of vaso-occlusive events. It was approved by the FDA for the

Northwell facility in New Hyde Park. He couldn’t travel without going to a hospital, had a hard time working a job, and had to stop going to Queens Community College because of recurring issues with the disease, which made his life substantially challenging. When Lyfgenia became available when it

and intense pain if damaged red blood cells block vessels and restrict oxygen supply, which can also lead to strokes and heart failure. Beauzile, had his first of many crises from his extremely severe case of sickle cell as a 4-month-old baby. Since then, he has consistently been in and out of the

What is Sickle Cell Disease (SCD)?

mutation (mutation in the HBB gene) causes red blood cells to become irreversibly sickle shaped, which can lead to haemolytic anaemia- a blood condition that occurs when your red blood cells are destroyed faster than they are replaced. Over a long period, the disorder can cause severe organ damage

descent. According to the center’s Director of Pediatric Hematology, Oncology, and Stem Cell Transplantation: THIS IS A FIX. Other drugs modify the disease, but this is a CURE and they suspect this genetic treatment will replace bone marrow transplants in time. In sickle cell disease, a gene

In a significant medical breakthrough, Long Island's Sebastien Beauzile has become the first person in New York to be cured of sickle cell anemia, a genetic disease that causes chronic pain and a host of other health issues, primarily affecting people of African, Mediterranean, and Middle Eastern

THIS IS INCREDIBLE! Cohen Children’s Medical Center has confirmed that it has successfully ELIMINATED sickle cell disease from Sebastien Beauzile, using the groundbreaking genetic treatment Lyfgenia. He has made HISTORY by becoming the FIRST in New York to be CURED of sickle cell anemia! 🧪🧵⬇️

THIS IS HUGE! Researchers at Cornell University have developed a new thermostable, MULTI-TARGET vaccine platform that offers stronger, longer-lasting protection against SARS-CoV-2 AND influenza while providing broader immunity against VARIOUS flu strains. 🧪🧵⬇️

Disability increase from COVID in the US graph

An important graph and caption on the impact of Covid www.nytimes.com/interactive/...

Measles virus targets certain immune cells in the body: What to know about complications The virus targets certain types of immune cells in the body, destroying them in the process.

In case you've forgotten about measles induced immune amnesia
www.nbcnews.com/health/healt... w/ @michaelmina.bsky.social @virusesimmunity.bsky.social

Screenshot of article linked here: https://pdf.sciencedirectassets.com/271205/1-s2.0-S0264410X25X00098/1-s2.0-S0264410X25002919/main.pdf

My co-EIC Florian Krammer wrote this commentary in Vaccine on the need for next generation flu vaccines to have a NA component (the N in H5N1 or H3N2).

It’s a smart idea & safeguards against bad matches to HA & other subtypes that share N1 or N2.

THIS IS HUGE! Researchers at Stanford University have developed a dual-antibody treatment that remains effective against ALL SARS-CoV-2 variants by targeting a less-mutable part of the virus. This breakthrough could lead to longer-lasting therapies that OUTPACE viral evolution. 🧪🧵⬇️

We have these up in VA02…

My hometown of Waterloo, Iowa canceled its African American Read-In after Trump’s anti-diversity directives. So i got together some writer friends and I’m holding it instead.

Very little can help my general mood of despair, but my goodness, this did..
x.com/timjacobwise...