Eric Hall

NSERC submitted! Time for a celebratory beer and a nap!

Yes. I'm always happy to go over cool images and data!

They are metastatic breast cancer cells. They have wild amounts of various intercellular projections!

As spooky season is upon us 🎃, we have cells that look like spider webs for #FluorescenceFriday 🧪🔬

This is a great lab, doing incredibly exciting research! 🧪🔬

YouTube video by Kurzgesagt – In a Nutshell AI Slop Is Killing Our Channel

[stands up soapbox] I know AI has its benefits, but the current general implementations of LLMs is breaking referencing and reviews in research, and I hate it! 😫 Not to mention the internet as a whole. Kurzgesagt, again gives a great example of the problem.
youtu.be/_zfN9wnPvU0?...

We are pleased to share that CHRIM is seeking our next CEO/Scientific Director! If you want to join a unique environment where collaboration sparks innovation, see the full job posting here: tinyurl.com/3dkcsdmh

Please feel free to share this job posting with your networks!

Great work by Sheikh Faisal Asadullah Mahdi, showing us his work on cytonemes in brain cancers at the Prairie Cancer Consortium today!

After seeing
@miguelcmestre.bsky.social @lancasterlab.bsky.social @jamesdmanton.bsky.social
's paper this week on deep and accessible ExM imaging with cerebral organoids, I think it's a good time to repost this Starter Pack of Expansion Microscopy people!
go.bsky.app/Qxks9WD

Also Prague is pretty great😉

Great talk from @hc327.bsky.social at the 7th annual CCP Phenogenomics Conference! Dr Chen shows how rare disease foundations can really facilitate fantastic scientific progress directly helping patient families!

FlyBase needs your help! We ask that European labs continue to contribute to Cambridge, UK FlyBase, whereas US and other non-European labs can contribute to US FlyBase. For more information and how to donate: wiki.flybase.org/wiki/FlyBase...

The lab keeps growing, as we wrap up the end of a great summer of research for summer student Shelby and welcome our new Masters student Sakshi!

I still can't get over how cool cells can be reaching out and interacting with one another! This depth shaded membrane marker gives us an idea of how dynamic these extensions can be! #FluorescenceFriday 🔬🧪

This doe looks so unimpressed with having me snap a pic while dealing with 3 hungry fawns.

Im procrastinating locking myself in my office for grant writing this afternoon. Im having way more fun on the 🔬 for #FluorescenceFriday

Yes! It has been non-stop for a while now 🙄

Congrats to the whole team!

Happy Friday! It's always stressful the first time trying to mount coverslips, but huzzah! No broken coverslips for summer student Shelby Houston, thanks to great guidance by technician Shakila Sultana!

Hey 🧪🔬🧑‍🔬Does anyone have an opinion on a preferred vibratome for tissue sectioning?
I'm looking at options. I've used several Leica models in the past, all great, but other companies seem to be great for the price.

Gotta love coming home to Nelson to be able to go play in the snow in June.

Fantastic talk from Gurpreet Moroak from @estherverheyen.bsky.social group! Giant larvae at the Canadian Developmental Biology conference!

Here we have Eric Hall, University of Manitoba talking about "Uncovering cytoneme regulated signaling events in spinal cord development". Fun fact, Dr. Hall did their undergrad here at UBCO in Kelowna, the 2025 Canadian Developmental Biology Conference venue! #CDBC2025 @socdevbio.bsky.social

🚨 BMG publication alert! 🚨

Congratulations to Danielle Pascual, ‪@marcogliese.bsky.social‬ and the rest of the BMG team on their latest publication - Excess Wnt in neurological disease

Read more here: portlandpress.com/biochemj/art...

Excited to share my latest paper from @stjuderesearch.bsky.social , where we leverage patient derived cortical organoids to study UBA5 associated neurodevelopmental disorders.

Patient-derived models of UBA5-associated encephalopathy identify defects in neurodevelopment and highlight potential therapeutic avenues Patient-derived cortical organoids facilitate disease modeling and assessment of potential targeted therapies for UBA5-related disorder.

Massive congratulations to @hc327.bsky.social and the all the Mefford lab @hcmefford.bsky.social !!! Patient-derived models of UBA5-associated encephalopathy identify defects in neurodevelopment and highlight potential therapeutic avenues, is now out! www.science.org/doi/10.1126/...

Have you ever wondered how GPCRs co-occupying the primary cilium might engage in cross talk? @stjuderesearch.bsky.social Graduate Student Christina Wang 👩‍🔬 wrote a BioEssay hypothesizing 5 testable models for ciliary receptor cross talk ✅ it out 🧪

onlinelibrary.wiley.com/share/author...

For #FluorescenceFriday 🔬 we have an endothelial cell 🔵 with #cytonemes carrying vesicles (bright cyan dots) to deposit signaling proteins on distant receiving cells. 🟣= actin
Image by Morgan Hiebert

Manitoba researchers decry funding cuts after premier's invitation to U.S. scientists | CBC News A call from Manitoba Premier Wab Kinew for scientists in the U.S. to consider moving here has researchers in this province demanding more funding to give those who relocate a reason to stay.

Manitoba scientists decry provincial funding cuts to research after Kinew overture to U.S. academics www.cbc.ca/news/canada/...

Its FINALLY here! The first #FluorescenceFriday 🧪🔬out of the Hall lab! We're still in the process of optimizing different fixatives to look for cytonemes and cellular extensions, but a fantastic first time imaging them from Morgan Hiebert!