Hatley Lab

Non-cell-autonomous tumor promotion in DICER1 cancer predisposition Patients with DICER1 cancer predisposition typically harbor a germline heterozygous inactivating mutation in DICER1. Whether DICER1 mutant non-cancerous cells contribute to tumor promotion was previou...

Proud to share a new paper in Developmental Cell! This project spans over a decade of work and it's been amazing to see it all come together. Huge cheers to Randy, @hatleylab.bsky.social and the rest of the team! www.cell.com/developmenta...

30.09.2025 03:00 — 👍 1    🔁 2    💬 0    📌 0

Non-cell-autonomous tumor promotion in DICER1 cancer predisposition Patients with DICER1 cancer predisposition typically harbor a germline heterozygous inactivating mutation in DICER1. Whether DICER1 mutant non-cancerous cells contribute to tumor promotion was previou...

Non-cell-autonomous tumor promotion in DICER1 cancer predisposition: Developmental Cell www.cell.com/developmenta...

29.09.2025 15:06 — 👍 0    🔁 0    💬 0    📌 0

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence Gadek et al. show that embryonal rhabdomyosarcoma formation is defined by the presence of primary cilia and limits SHH pathway competency in early endothelial progenitor cells that disappear during em...

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence: Cell Reports www.cell.com/cell-reports...
Latest from @hatleylab.bsky.social

25.09.2025 13:46 — 👍 5    🔁 2    💬 0    📌 1

Stellar Hatley grad students took 1st and 2nd place oral presentations at the St. Jude PhD symposium! @stjudegraduate @StJudeResearch

17.09.2025 22:47 — 👍 1    🔁 0    💬 0    📌 1

Stem Cell Podcast on X: "We have a new episode out now! Learn how Dr. Mark Hatley (@hatleylab) from @StJudeResearch is using #rhabdomyosarcoma to study the developmental origins of pediatric cancer: https://t.co/qb9GVwiipX https://t.co/KCed7K6pBN" / X We have a new episode out now! Learn how Dr. Mark Hatley (@hatleylab) from @StJudeResearch is using #rhabdomyosarcoma to study the developmental origins of pediatric cancer: https://t.co/qb9GVwiipX https://t.co/KCed7K6pBN

x.com/stemcellpodc...

06.08.2025 15:17 — 👍 0    🔁 0    💬 0    📌 0

Hatley lab grad students represent! Randy Larsen won St Jude Grad School Research Achievement Award and Bradley Stevens with an honorable mention. We appreciate all our great students!

11.04.2025 21:30 — 👍 0    🔁 0    💬 0    📌 0

Great to be @cedars-sinai.bsky.social meeting with regenerative medicine institute investigators. Terrific group of innovative scientists.

26.03.2025 20:24 — 👍 0    🔁 0    💬 0    📌 0

Tune in today to the Science of Childhood Cancer series from the St Jude Comprehensive Cancer Center featuring Dr. Martine Roussel. @molonc-stjude.bsky.social www.stjude.org/education-tr...

06.02.2025 15:21 — 👍 2    🔁 2    💬 0    📌 0