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Bailey Tischer

@baileytischer.bsky.social

Chemistry and Biology at MIT | Class of 2026 | Li Lab at @whiteheadinstitute.bsky.social

16 Followers  |  35 Following  |  1 Posts  |  Joined: 22.11.2024  |  1.2628

Latest posts by baileytischer.bsky.social on Bluesky

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Hierarchical lineage architecture of human and avian spinal cord revealed by single-cell genomic barcoding The formation of neural circuits depends on the precise spatial and temporal organisation of neuronal populations during development. In the vertebrate spinal cord, progenitors are patterned into mole...

Thrilled to share my main postdoc work with @jamesbriscoe.bsky.social

We used genomic barcoding + scRNAseq in chick & human embryos to reveal a lineage architecture that reshapes how we understand neural tube development & cell fate decisions
πŸ§΅πŸ‘‡

www.biorxiv.org/content/10.1...

26.10.2025 17:15 β€” πŸ‘ 160    πŸ” 48    πŸ’¬ 6    πŸ“Œ 6

Complexity is a consequence of the fact that it’s easier to add than to subtract.

Take evolution of lungs from swim bladders as an example. A lungfish gradually emerges arising from its competitive advantages in living in and out of water.

No creature with lungs has reversed the process.

31.05.2025 16:42 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is so exciting! Congratulations!

22.03.2025 23:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

Excited to share my latest work with @joadelas.bsky.social and @jamesbriscoe.bsky.social

Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

www.biorxiv.org/content/10.1...
1/11

10.03.2025 13:28 β€” πŸ‘ 59    πŸ” 26    πŸ’¬ 4    πŸ“Œ 5
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Predictable Engineering of Signal-Dependent Cis-Regulatory Elements

Our latest: uncovering hierarchical design rules for cis-regulatory elements with a high-throughput screen

CRE activity follows multiplicative modular rules, tuned by spacing & positioning

Enables engineering synthetic CREs for predictable tissue patterning

www.biorxiv.org/content/10.1...

10.03.2025 04:19 β€” πŸ‘ 95    πŸ” 27    πŸ’¬ 3    πŸ“Œ 2

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