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Khaled_Selim Lab

@selimlab.bsky.social

Microbiology | Cell Signaling | Structural Biology | Institute of Phototrophic Microbiology @hhu.de https://www.phototrophic-microbiology.hhu.de/en/ Central Metabolism Coordination by #PII & #cdiAMP & #cdiGMP & #Ca2+ signaling #Cyanobacteria

314 Followers  |  282 Following  |  185 Posts  |  Joined: 16.01.2025  |  1.8525

Latest posts by selimlab.bsky.social on Bluesky

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A structural perspective on ฮฑโ€glucan catabolism in oxygenic phototrophs Efficient mobilization of carbon storage polymers is essential for the survival of oxygenic phototrophs under fluctuating environmental conditions. Recent structural studies have uncovered the molecu....

One of the first reviews at our special issue Plant structural biology: insights & technology @theplantjournal.bsky.social

Congrats @doellosofia.bsky.social & @dmitryshvarev.bsky.social

#cyanobacteria

onlinelibrary.wiley.com/doi/10.1111/...

13.02.2026 21:38 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Stages of biomolecular condensate formation in pro-ฮฒ-carboxysome assembly - Nature Plants Carboxysomes are cyanobacterial CO2-concentrating compartments with a proteinaceous shell. The elucidation of the role of the shell adaptor protein ApN in stepwise ฮฒ-carboxysome assembly will aid the ...

Stages of biomolecular condensate formation in pro-ฮฒ-carboxysome assembly www.nature.com/articles/s41...

11.02.2026 08:57 โ€” ๐Ÿ‘ 8    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Stressed About The World? Take A Cue From Cyanobacteria In turbulent times, it helps to hear stories of resilience. What can we learn from 3.5 billion-year-old bacteria that eat light?

www.sciencefriday.com/segments/lig...

12.02.2026 01:16 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congrats Florent, Ben @cellarchlab.com & team!

11.02.2026 20:07 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Long in the making, but happy to present the Chlamydomonas chlororibosome!
Cryo-ET๐Ÿ”ฌreveals a large new domain on the small subunit, built from multiple extensions in conserved ribosomal proteins.
bioRxiv ๐Ÿ“–: shorturl.at/q44tG
This suggests greater chlororibosome diversity than expected!
1/n ๐Ÿงต

10.02.2026 08:35 โ€” ๐Ÿ‘ 148    ๐Ÿ” 53    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 6
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AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution By solving a previously unsolved biological question, the AI co-scientist predicted a complex mechanism of gene transfer and generated hypotheses that opened new research directions, illustrating AI's...

AI mirrors experimental science to uncover a mechanism of gene transfer crucial to bacterial evolution

www.cell.com/cell/fulltex...

09.02.2026 21:57 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congrats Ben! and team
@botbml.bsky.social

07.02.2026 22:29 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Functional characterisation of bicarbonate transporters from the cyanobacterial SbtA2 family and subsequent expression in tobacco Abstract. Cyanobacteria rely on bicarbonate (HCO3-) as the primary inorganic carbon (Ci) source for photosynthesis in aquatic environments. To use this Ci

Functional characterisation of bicarbonate transporters from the cyanobacterial SbtA2 family and subsequent expression in tobacco academic.oup.com/jxb/article/... @jxbotany.bsky.social

06.02.2026 18:44 โ€” ๐Ÿ‘ 8    ๐Ÿ” 9    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Seasonal cycles select for self-sustained circadian oscillators Circadian clocks comprise self-sustained oscillators that anticipate time-of-day changes in the environment. Dani et al. report that seasonal changes in daylength can alone provide a strong selective ...

Seasonal cycles select for self-sustained circadian oscillators: Current Biology www.cell.com/current-biol...

05.02.2026 09:43 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Happy to announce that our review article on vesicle-coupled mRNA trafficking is now availalbe

@mibinet.bsky.social

#EMBOrnaLocalization

link.springer.com/article/10.1...

02.02.2026 15:56 โ€” ๐Ÿ‘ 12    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Resurrected nitrogenases recapitulate canonical N-isotope biosignatures over two billion years - Nature Communications The study shows that nitrogenase enzymes have maintained stable isotope signatures over billions of years, revealing how ancient microbes shaped Earthโ€™s nitrogen cycle and offering a new experimental ...

Our new paper, out today! We resurrected ancient nitrogenases first used by life on Earth 3 billion years ago. We combined synthetic biology and geology & validated their chemical #biosignature in rocks that helps reveal ancient life on Earth!(and beyond!)

Link: www.nature.com/articles/s41...

30.01.2026 21:12 โ€” ๐Ÿ‘ 66    ๐Ÿ” 23    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3

Congrats @synbiojazz.bsky.social !

29.01.2026 18:41 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Researchers led by Jun.-Prof. Dr. Julie Zedler at #UniJena have developed a sustainable alternative to synthetic food colourings: they have modified cyanobacteria so that they produce yellow natural colourings from light and carbon dioxide alone.

โžก๏ธ www.uni-jena.de/en/386595/gelโ€ฆ

29.01.2026 16:00 โ€” ๐Ÿ‘ 6    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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A prophage-encoded abortive infection protein preserves host and prophage spread - Nature A Gifsy-1 prophageโ€“encoded higher eukaryotes and prokaryotes nucleotide-binding protein, HepS, senses Siphoviridae infection, activates abortive defence by cleaving host transfer RNAs, blocks rival ph...

A prophage-encoded abortive infection protein preserves host and prophage spread www.nature.com/articles/s41...

28.01.2026 19:13 โ€” ๐Ÿ‘ 42    ๐Ÿ” 20    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Formation & function of #MembranelessOrganelles! #CryoET structures of #proteasome storage granules inside cells!
Read our paper @cp-cell.bsky.social!

โ•Publication: doi.org/10.1016/j.ce...
โ•Press Release: www.biochem.mpg.de/en/pressroom

@uoftmedicine.bsky.social
@erc.europa.eu #UPSmeetMet

28.01.2026 16:39 โ€” ๐Ÿ‘ 68    ๐Ÿ” 26    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
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Jobs View the current job vacancies at the Microbiology Society.

We are looking for new editors for Microbiology, the flagship journal of @microbiologysociety.org

Deadline for applications is 16 Feb 2026

microbiologysociety.org/who-we-are/j...

28.01.2026 08:44 โ€” ๐Ÿ‘ 9    ๐Ÿ” 19    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
AI tool โ€œHelixerโ€ identifies genes in newly sequenced organisms Researchers at Forschungszentrum Jรผlich and Heinrich Heine University Dรผsseldorf have developed a tool that could significantly transform genome research: Helixer identifies genes directly from DNA se...

New AI tool โ€œHelixerโ€ identifies genes in newly sequenced organisms. Helixer identifies genes directly from DNA sequences.

Developed by team around @usadellab.bsky.social @fz-juelich.de, @apmweber.bsky.social , @sebtriesch.bsky.social @hhu.de et al. www.fz-juelich.de/en/news/arch...

26.01.2026 18:04 โ€” ๐Ÿ‘ 11    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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PII interactions with the acetyl-CoA carboxylase subunits BADC and BCCP co-regulate lipid and nitrogen metabolism in Arabidopsis The PII protein regulates fatty acid synthesis and through interactions with biotin/lipoyl attachment domain containing and biotin carboxyl carrier protein

PII interactions with the acetyl-CoA carboxylase subunits BADC and BCCP co-regulate lipid and nitrogen metabolism in Arabidopsis (Matthew G Garneau , Gabriel Lemes Jorge , Jay Shockey , Jay J Thelen , Philip D Bates) doi.org/10.1093/plph... #PlantScience @aspbofficial

26.01.2026 18:57 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congrats @tiffzarrella.bsky.social and team!

24.01.2026 14:15 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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WE ARE #HIRING: [reposting=๐Ÿ‘Œ ๐Ÿ™ ]
2 funded positions for #nanopore related projects @unibas.ch ๐Ÿ‡จ๐Ÿ‡ญ:
1๏ธโƒฃ #PhD Candidate in Single-Molecule Biophysics using Nanopore Trapping.
2๏ธโƒฃ #PhD Candidate in Microplastic Detection Using Micropores and Microfluidics.
More info: schmid.chemie.unibas.ch/en/join-us-1/

23.01.2026 19:23 โ€” ๐Ÿ‘ 3    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Congrats David and team!

22.01.2026 18:03 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Genomic clues to the origin of eukaryotic cells How did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers.

How did eukaryotic cells with complex architecture evolve from simpler prokaryotic cells? DNA analyses offer possible answers @nature.com
www.nature.com/articles/d41...
www.nature.com/articles/s41... @bristoluni.bsky.social
www.nature.com/articles/s41...
www.nature.com/articles/s41...

15.01.2026 16:43 โ€” ๐Ÿ‘ 27    ๐Ÿ” 18    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

www.ufz.de/index.php?en...
Here ist a small press about our recent findings about Guanidin metabolism in #cyanobacteria

Toxicity vs. Uptake & Catabolism

A great collaboration between @ufz.de & @hhu.de & @unihalle.bsky.social

HERE is the original publication @pnas.org
www.pnas.org/doi/10.1073/...

15.01.2026 17:59 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

New enzyme with dual function as methionine synthase and a glycine betaine methyltransferase

Methionine synthesis and glycine betaine demethylation are intricately intertwined in cosmopolitan marine bacteria

www.pnas.org/doi/full/10....

14.01.2026 09:37 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
A Novel Biosensor for Ferrous Iron Developed via CoBiSe: A Computational Method for Rapid Biosensor Design Genetically encoded biosensors enable the monitoring of metabolite dynamics in living organisms. We present CoBiSe, a computational biosensor design approach using Constraint Network Analysis to ident...

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

12.01.2026 09:48 โ€” ๐Ÿ‘ 10    ๐Ÿ” 8    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Happy to share our recent preprint:
"DNA-intercalating antiphage molecules trigger abortive infection through mutual destruction and synergize with bacterial immunity"

www.biorxiv.org/content/10.6...

@spp2330.bsky.social, @mibinet.bsky.social, @dfg.de @hhu.de @fzj.bsky.social

14.01.2026 08:57 โ€” ๐Ÿ‘ 44    ๐Ÿ” 26    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Ancestral sequence reconstruction reveals CTP-dependent loading of the bacterial centromere-binding protein ParB as an ancient evolutionary feature

Now published:
tinyurl.com/4ddhwbb3

Thanks to the Hochberg and Bange labs for the great collaboration!

09.01.2026 19:44 โ€” ๐Ÿ‘ 27    ๐Ÿ” 12    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
Opportunity Details - Faculty Opportunities

We are hiring new faculty!! Come join our amazing community in the Department of Molecular Microbiology at Washington University School of Medicine! The deadline for applications is 2/21, but applications will be reviewed on a rolling basis. facultyopportunities.wustl.edu/Posting/Deta...

08.01.2026 21:05 โ€” ๐Ÿ‘ 27    ๐Ÿ” 42    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Client Challenge

๐Ÿซด Genetic switch between unicellularity and multicellularity in marine yeasts:

www.nature.com/articles/s41...

@nature.com

08.01.2026 15:11 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
2026 Microbial Stress Response Conference GRC The 2026 Gordon Research Conference on Microbial Stress Response will be held in South Hadley, Massachusetts. Apply today to reserve your spot.

Registration is open for the 2026 Gordon Research Conference on Microbial Stress Response to be held on July 19-24 2026!! Submit your abstract by February 15th to be considered for a short talk. Apply now before it fills up!! Hope to see you there!! www.grc.org/microbial-st...

06.01.2026 19:15 โ€” ๐Ÿ‘ 24    ๐Ÿ” 23    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

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