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Markus Deserno

@markusdeserno.bsky.social

Theoretical and computational biophysicist at Carnegie Mellon University. Loves lipid membranes, music, and art. (he/him) πŸ‡©πŸ‡ͺπŸ‡ΊπŸ‡Έ

1,370 Followers  |  174 Following  |  1,136 Posts  |  Joined: 17.11.2024  |  1.954

Latest posts by markusdeserno.bsky.social on Bluesky

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Happy 94th Birthday to πŸ‡ΊπŸ‡ΈAmerican composer, conductor and pianist #JohnWilliams KBE born #OnThisDay in Queens, New York City

08.02.2026 15:49 β€” πŸ‘ 216    πŸ” 60    πŸ’¬ 12    πŸ“Œ 7

I have 3 Excel sheets open, none bigger than 30kB. How is it that Excel uses 1,6GB of memory? How, Microsoft??? How have you become SO BAD at efficient programming that I need 20,000 times the memory of the Apollo Guidance Computer, which landed on the moon, to collate student grades? DO BETTER!

07.02.2026 23:58 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again.
#Pinks #ProudBlue

05.02.2026 11:50 β€” πŸ‘ 31507    πŸ” 13578    πŸ’¬ 594    πŸ“Œ 1611

Like not understanding the difference between a radio and a station.

04.02.2026 18:17 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

You missed 4 zeros.

03.02.2026 12:21 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Need to get rid of all that ICE.

02.02.2026 13:35 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I appreciate the addition of Pluto. πŸ’ͺ

02.02.2026 01:26 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Don’t you think that’s a little dangerous?

01.02.2026 14:55 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Doesn’t look particularly wet to me.

31.01.2026 01:29 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Awesome colleague alert!
One day, @bridgesbio.bsky.social might save your life by disrupting bacterial communication and behavior. No need to kill your enemyβ€”just confuse the heck out of them!

31.01.2026 01:25 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Many have already shared this powerful image by MJ.Hiblen, over on Insta under www.instagram.com/mjhiblenart/. It really makes me well up. May RenΓ©e and Alex rest in peace. πŸ’”

27.01.2026 17:19 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Because of the victims.

27.01.2026 11:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Just like I don’t want to go to war zones to bear witness to atrocities first hand, I don’t want to watch snuff videos to confirm that ICE is executing protestors in broad daylight. I want professional journalists to do that. And I don’t want them to both-sides the content. DO YOUR JOB!

26.01.2026 12:59 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Martens, Turkowyd, Hohlbein, and Endesfelder would politely disagree! πŸ§ͺ

26.01.2026 12:31 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Kudos to the NYT editor who took β€œAppears to” out of the lead headline (finally)

25.01.2026 15:18 β€” πŸ‘ 9838    πŸ” 1962    πŸ’¬ 189    πŸ“Œ 106

Oh, apparently just one day.
bsky.app/profile/froo...

26.01.2026 12:25 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas.

Vibrant color portrait of Jane S. Richardson, the visionary biophysicist and artist who revolutionized structural biology with her invention of ribbon diagrams. She gazes warmly at the camera with a bright, knowing smile that radiates quiet brilliance and decades of curiosity. Her silver-blonde hair woven with gentle waves. Large, elegant dangling earrings catch the light, and she wears a richly patterned brown blouse embroidered with intricate turquoise paisley motifs and delicate beadwork that echoes the molecular elegance she has spent her life depicting. Behind her floats a luminous, dreamlike backdrop of glowing molecular structures--interlocking hexagonal and ribbon-like forms in electric blues, teals, and greens--blending science and art in a single, living canvas.

Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or β€œribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent Ξ±-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of Ξ²-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustrationβ€”a timeless bridge between molecular reality and human imagination.

Hand-drawn and hand-colored (by Jane Richardson) scientific artwork known as a Richardson ribbon diagram (or β€œribbon model”), one of the iconic visual inventions of Jane Richardson that transformed the way we see and understand protein structures. A graceful, three-dimensional tangle of protein backbone ribbons twists and spirals through space, rendered in soft pencil lines and luminous watercolor hues. Smooth golden-brown coils represent Ξ±-helices that curl like elegant ribbons, while broad teal-green arrows trace the flat, pleated strands of Ξ²-sheets slicing through the molecule with directional purpose. Thin, looping golden threads connect the secondary structures, creating a delicate, almost dance-like choreography of biology’s hidden architecture. The entire form is framed by a simple olive-green mat and dark border, giving the drawing the quiet dignity of both fine art and precise scientific illustrationβ€”a timeless bridge between molecular reality and human imagination.

Jane Richardson was born #OTD in 1941

+ Developed the Richardson (ribbon) diagram to represent proteins' 3D structure (becoming a standard representation for protein structures)
+ MacArthur Fellow, 1985
+ Elected, Nat'l Academy of Sciences, 1991
+ President, Biophysical Society, 2012

#WomenInSTEM

26.01.2026 00:06 β€” πŸ‘ 263    πŸ” 93    πŸ’¬ 3    πŸ“Œ 7

So you’re saying Byron was the Malcolm Gladwell of the day? πŸ€”

25.01.2026 14:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Ooh, a rare picture of Evans without a cigarette!

25.01.2026 14:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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How long until the word β€œappear” disappears? Not holding my breath.

25.01.2026 14:23 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

β€œGet it all on record now β€” get the films β€” get the witnesses β€” because somewhere down the road of history some bastard will get up and say that this never happened.”

Dwight D. Eisenhower, after visiting liberated concentration camps in April 1945

24.01.2026 21:24 β€” πŸ‘ 12867    πŸ” 4737    πŸ’¬ 123    πŸ“Œ 97

Alex Pretti was a colleague at the VA. We hired him to recruit for our trial. He became an ICU nurse- I lover working with him. He was a good kind person who lived to help and these fuckers executed him.

White. Hot. Rage.

24.01.2026 19:31 β€” πŸ‘ 60713    πŸ” 18964    πŸ’¬ 1406    πŸ“Œ 743
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β€œFreedom is not free. We have to work at it. Nurture it. Protect it. Even sacrifice for it.”

25.01.2026 02:56 β€” πŸ‘ 17834    πŸ” 7115    πŸ’¬ 421    πŸ“Œ 481

I was a sensitive kid. I loved cats. I had OCD, undiagnosed.

When I was 9, a fraternity brother tortured a cat to death in my hometown. The details even now are beyond imagination. archive.is/xdmUL

I was traumatized for years from reading the news story.

The torturer? Now the head of the NRA.

25.01.2026 04:55 β€” πŸ‘ 9945    πŸ” 3052    πŸ’¬ 325    πŸ“Œ 257

A reminder to the news media: β€œconflicting accounts” is what you say BEFORE the incontrovertible video evidence appears. After that, your job is to ask why one side is lying, not to repeat the lie and pretend no one knows the truth.

25.01.2026 12:28 β€” πŸ‘ 47566    πŸ” 14352    πŸ’¬ 524    πŸ“Œ 603

Anywaysβ€”enjoy the festivities!

24.01.2026 18:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Maybe redefine ℏ = h / 2Ο€i ?

24.01.2026 18:41 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Maybe the minus sign is on the back? πŸ€”

24.01.2026 18:34 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Stay strong! I am so sorry and worried about y’all!

24.01.2026 00:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Agree on the inks! And the Lamy Al-Star is also an immensely solid choice!

23.01.2026 23:55 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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