Anurag Adhikari, PhD

New opportunity to help sustain global health research

re-fund-global-health.vercel.app

Characterizing Long COVID Symptoms During Early Childhood.
jamanetwork.com/journals/jam...

Thank you to our reviewers: @Anna.Durbin @sbiering.bsky.social @vasiliya-kril.bsky.social @Eng.Eong.Ooi @anuragadhikari.bsky.social @Sujan.Shresta @Pradhan.Aunji

Preprint author(s): @Bobby.Brooke.Herrera

Reviews of Reviewer(s): A Durbin (Johns Hopkins University) | 📒📒📒 ◻️◻️ • S Biering & V Kril (UC San Diego) | 📒📒📒◻️◻️ • E E Ooi (Duke-NUS Medical School) | 📘📘📘📘📘 • A Adhikari & S Shresta & P Aunji (La Jolla...

🔊🚨‼️Check out our reviews on whether immunity to yellow fever can be protective towards Dengue virus too!
rrid.mitpress.mit.edu/pub/ipcox645...

As a first #ImmunoSky post, I’m excited to share our latest pre-print, by the fantastic Mitchell Zheng!

www.biorxiv.org/content/10.1...

Our group is interested in virus-specific CD4 T cells, which means we often use in vitro stimulations (like the AIM assay) to find our cells of interest. 🧵 1/9

I’ve tried to put together a starter pack of immunologists/scientists exploring B Cell Repertoires and Antibody Affinities.

Please feel free to share/join!

go.bsky.app/4P64DmM

I can't even count how many times the visa issue has been an iron gate to attend/ present in scientific conference in these visa hostile countries, both for me and my trainees 😔. There is a clear need to shift the power and do such meetings in visa friendly countries, which btw are many.

Visa-friendly venues for global health meetings Conference organizers have an obligation to host meetings in locations that are not visa-hostile. Are there ‘visa-friendly’ options that conference organizers should be considering? This crowd-sourced...

Ask anyone from a Global South country, and they will immediately point out the most visa-hostile countries: USA, UK, Canada, EU (Schengen), and Australia would top the list

communities.springernature.com/posts/visa-f...

Coupling antigens from multiple subtypes of influenza can broaden antibody and T cell responses

A monozygotic twins and vaccinated newborns study with an old twist: antigen conjugation to full T cells in providing broad B cell help!

www.science.org/doi/...
1/10

Finally got on Bluesky to share some work I'm really proud of...

Using a tiled amplicon approach, we were able to sequence TB directly from sputum, without culture. This could help make WGS of TB (which can take weeks to culture) much faster at a similar price point to widespread SC2 sequencing.

Trump’s Return May Worsen Financial Woes for Global Health Institutions The U.S. provides nearly half of the aid for global health, including childhood vaccination, H.I.V. treatment and disease surveillance.

Health of the world should never be reliant on any one country

Global South governments must invest more in health and become less reliant on aid

www.nytimes.com/2024/12/19/h...

How America Lost Control of the Bird Flu, Setting the Stage for Another Pandemic - KFF Health News Exclusive reporting reveals how the United States lost track of a virus that could cause the next pandemic. Problems like the sluggish pace of federal action, a deference to industry, and neglect for ...

💥 My 2024 Mile Marker: The inside scoop on how America lost control of the Bird Flu, opening the door for another pandemic.

"We're in a terrible situation" said @angierasmussen.bsky.social

🧵Here's how we got here & how to get out @kffhealthnews.bsky.social kffhealthnews.org/news/article...

The Mystery Illness That Never Was Poverty and Healthcare Inequities as Modern Outbreaks

The mystery illness in the #DRC was revealed to be #Malaria. The world will move on and the epidemics of poverty and inequity to healthcare access will persist. We cannot address the threat of pandemics by ignoring poverty.
Check out my latest #substack on this
open.substack.com/pub/bktitanj...

Neglect, it is.

WHO finds that the direct cause of "the mystery disease" in Congo is malaria, exacerbated by malnutrition. Malaria can be *cured* by a few cheap pills, as long as it's caught early. So these are deaths of neglect.

www.reuters.com/world/africa...

Confronting risks of mirror life Broad discussion is needed to chart a path forward.

Life isn't even-handed: many cellular components are all either left or right handed. But we are now (uncomfortably) close to being able to make flipped "mirror" cells. A group of us consider and highlight the risks and call for collective effort before we get there.
www.science.org/doi/10.1126/...

Safety and efficacy of the blood-stage malaria vaccine RH5.1/Matrix-M in Burkina Faso: interim results of a double-blind, randomised, controlled, phase 2b trial in children RH5.1/Matrix-M appears safe and highly immunogenic in African children and shows promising efficacy against clinical malaria when given in a delayed third-dose regimen. This trial is ongoing to further monitor efficacy over time.

Really cool to see more malaria vaccine candidates in advanced stage clinical trials. Ph2b trial of an erythrocyte stage merozoite targeting vaccine. It was safe, immunogenic and showed modest protective efficacy of 40% in infants 5-17 months.
www.thelancet.com/journals/lan...

Today, I travelled back in time, to the pre polio vaccine era

I closed my eyes, imagined being paralyzed… unable to breathe

I imagined being stuck in this claustrophobic iron lung, to breathe

Maybe we all need to time travel, to appreciate how science & public health saves us, every day.

Are you a senior PhD student or postdoc? Do you have a cool science story to tell? Do you want to visit Buffalo when the weather is perfect? Then apply for the Emerging Leaders Seminar Series at Roswell Park! DM or email me with questions. (RT please!)

www.roswellpark.org/education/pr...

I cannot understand that the US can’t just stop selling of raw milk with all that’s going on with H5N1 + implement strict biosafety on the farms. Do you know the level of protection required when working with the virus in the laboratory? The current situation US is a global health security risk

NIH Study Finds Tecovirimat Was Safe but Did Not Improve Mpox Resolution or Pain Study Examined Tecovirimat in Countries Affected by Global Clade II Mpox Outbreak.

The NIH STOMP shows that tecovirimat is safe, but doesn't expedite lesion healing or alleviate pain in persons with clade II mpox - study enrollment has been halted.

PALM 007 in DRC showed the same for clade I in DRC and emphasized the importance of supportive care

www.nih.gov/news-events/...

Postdoctoral Research Associate at King's College London Discover an exciting academic career path as a Postdoctoral Research Associate at jobs.ac.uk. Don't miss out on this job opportunity - apply today!

I am looking for 2 postdoctoral researchers to join my lab to work on the role of HIV-1 accessory proteins in the pathogenesis of HIV/AIDS and viral latency.

Please contact me informally or ‘re-sky’ to anyone you think may be interested. Closing Dec 10th

www.jobs.ac.uk/job/DKV639/p...

This doctor raised the alarm about a deadly mpox outbreak that went global Placide Mbala is part of Nature’s 10, a list of people who shaped science in 2024.

What a distinct pleasure it is to see this very well deserved recognition for such a great colleague and friend - Dr. Placide Mbala-Kingebeni 👏👏👏
www.nature.com/articles/d41...

Challenges for developing broad-based mucosal vaccines for respiratory viruses - Nature Biotechnology Nature Biotechnology - Challenges for developing broad-based mucosal vaccines for respiratory viruses

For those wondering why we seem to be so behind when it comes to effective mucosal vaccines against respiratory viruses, this really excellent overview from leaders in the field offers a great summary:
www.nature.com/articles/s41...

few additional points for those who want a bit more detail🧵:

The total mass, number, and distribution of immune cells in the human body | PNAS The immune system is a complex network of cells with critical functions in health and disease. However, a comprehensive census of the cells compris...

B CELL FUN FACT: Secrets of the GC #2

There are 300 billion B cells with total mass of 60g in the human body. That is 3 times the number of stars in the Milky Way! Naïve B cell express >10 million unique antibodies to protect us from this universe of possible antigens!

www.pnas.org/doi/10.1073/...

How the US National Institutes of Health is confronting health threats in a changing world The overall health and wellbeing of a population serves as a fundamental indicator of whether a society is meeting its people's most important needs. Achieving health for all people is only possible with educational opportunity, economic productivity, effective government, inter­national cooperation, and peace. As the single largest public funder of biomedical, behavioural, and social sciences research worldwide, the US National Institutes of Health (NIH) has a crucial role in promoting healthy societies.

This is a magnificent piece about how the NIH is “confronting health threats in a changing world,” here & worldwide

I fear that the men who Trump wants to lead HHS, which oversees NIH, and NIH will do untold damage; I hope I am wrong

www.thelancet.com/journals/lan...

We are opening a call for applications 2025 – Creation of new junior research groups at the Institut Pasteur in Paris @pasteur.fr all details on our web site : research.pasteur.fr/en/call/call...

Thanks Karim, happy to be included if it's not too late 😀

Two wonderful global health scholars have made their global health books free to download

Bravo and thanks @seyeabimbola.bsky.social and
@thewrittenro.bsky.social

The Foreign Gaze:
www.editions.ird.fr/open_access_...

Rethinking Global Health:
taylorfrancis.com/books/oa-mon...

Let's join together!!