Sophia Levis, MD, PhD's Avatar

Sophia Levis, MD, PhD

@sclevis.bsky.social

PGY-1 UC Irvine Psychiatry | MD/PhD from UC Irvine MSTP | NIDA NRSA Fellow | Interested in early life adversity, reward circuits, addiction | sc_levis on Twitter

3,865 Followers  |  381 Following  |  26 Posts  |  Joined: 27.08.2023  |  1.6851

Latest posts by sclevis.bsky.social on Bluesky

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Opioid drug seeking after early-life adversity: a role for delta opioid receptors Opioid use disorder (OUD) is associated with a history of early-life adversity (ELA), an association that is particularly strong in women. In a rodent…

Re-sharing over here the final chapter of my PhD now online as part of a special issue of Addiction Neuroscience on stress and addiction! We explore the link between adversity, addiction, and the role of delta opioid receptors in mediating that link:

04.12.2024 05:30 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Opioid drug seeking after early-life adversity: a role for delta opioid receptors Opioid use disorder (OUD) is associated with a history of early-life adversity (ELA), an association that is particularly strong in women. In a rodent…

Re-sharing over here the final chapter of my PhD now online as part of a special issue of Addiction Neuroscience on stress and addiction! We explore the link between adversity, addiction, and the role of delta opioid receptors in mediating that link:

04.12.2024 05:30 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Our study on ketamine's effects on neural self-other-distinction is finally out! πŸ₯³

This is the first really big project from my lab, so I am extra happy about this one 🀩.

#neuroskyence
#PsychSciSky
#AcademicSky
#philsci

27.06.2024 15:10 β€” πŸ‘ 21    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0
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Denver gave people experiencing homelessness $1,000 a month. A year later, nearly half of participants had housing. Participants in Denver's basic income program received up to $1,000 a month. They became more housing secure and landed full-time jobs.

Denver gave people experiencing homelessness $1,000 a month.

Results showed that close to half of the participants secured housing, and nearly $600K saved in public service costs due to fewer ER visits & jail stays. They also saw improved mental health.

25.06.2024 21:25 β€” πŸ‘ 3225    πŸ” 1142    πŸ’¬ 48    πŸ“Œ 106

The five stages of academic writing:

1. Procrastination
2. Panic
3. Caffeine overdose
4. Submitting a barely coherent mess
5. Swearing to do it differently next time
#academicsky

26.05.2024 17:38 β€” πŸ‘ 20    πŸ” 4    πŸ’¬ 0    πŸ“Œ 2
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Distinct Β΅-opioid ensembles trigger positive and negative fentanyl reinforcement - Nature Experiments using fentanyl treatment of mice show that Β΅-opioid receptors mediate positive reinforcement in the ventral tegmental area and negative reinforcement in central amygdala, thereby identifyi...

Some cool work showing negative valence of MOR-expressing neurons in the CeA during fentanyl withdrawal.


www.nature.com/articles/s41...

26.05.2024 15:04 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Dopamine, explained Dopamine detoxing, hacking, and fasting: Is any of it real?

Nice article pushing back on pop culture versions of dopamine

Featuring an all star dopamine scientist cast ⭐ - happy to see all these folks contributing!

www.vox.com/future-perfe...

22.05.2024 16:21 β€” πŸ‘ 28    πŸ” 15    πŸ’¬ 0    πŸ“Œ 2
Figure from our paper about nonbinary interpretations of sex differences in cognition, describing two suggestions. First, consider assessing strategies instead of performance, and second, consider whether sex impacts are variable and mosaic

Figure from our paper about nonbinary interpretations of sex differences in cognition, describing two suggestions. First, consider assessing strategies instead of performance, and second, consider whether sex impacts are variable and mosaic

Very happy to announce our paper!

"Sex mechanisms as nonbinary influences on cognitive diversity"

A pleasure to contribute to this special issue of Hormones and Behavior about how to be less binary and more inclusive in behavioral and cognitive neuroscience

www.sciencedirect.com/science/arti...

20.05.2024 19:26 β€” πŸ‘ 52    πŸ” 22    πŸ’¬ 2    πŸ“Œ 4
Post image Post image Post image Post image

After 8 long years, finally get to call myself a double doc! So grateful to my mentors, family, and my MSTP cohort, who are some of the most amazing and inspiring physician-scientists I know! πŸ§ͺ🩺🧠

20.05.2024 02:43 β€” πŸ‘ 5    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Very honored to have received the Meyskens Family research award and the department of Psychiatry outstanding graduating student award! Such an honor to be recognized among so many of my accomplished peers, and extra proud to have my family with me tonight to help celebrate! #medsky

18.05.2024 05:19 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0
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Postdoctoral Scholar University of California, Los Angeles is hiring. Apply now!

I’m looking for more post-docs to join our team at UCLA β˜€οΈ Please share with your 🧠 networks recruit.apo.ucla.edu/JPF09330

05.04.2024 02:59 β€” πŸ‘ 7    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
A two panel meme; on the left is an ornate horse capping the end of a wooden railing. The right is a toy horse taped to a pole at the bottom of stairs

A two panel meme; on the left is an ornate horse capping the end of a wooden railing. The right is a toy horse taped to a pole at the bottom of stairs

What I think I wrote vs what I realize I wrote when I’m editing

27.03.2024 23:47 β€” πŸ‘ 1155    πŸ” 210    πŸ’¬ 21    πŸ“Œ 16

Setting my watch to my dog’s position on the couch

09.03.2024 02:18 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
A white dog laying in a sunny spot on the couch. She’s using an orange stuffed squid as a pillow

A white dog laying in a sunny spot on the couch. She’s using an orange stuffed squid as a pillow

It’s hard work following the sunny spot around the house all day

09.03.2024 01:51 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Love this!! Do you have a link?

03.03.2024 16:53 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

🧠 hello #neuroskyence! happy to share my early career commentary in neuropsychopharmacology, highlighting the importance of understanding sex hormones for understanding the brain: www.nature.com/articles/s41...

19.02.2024 19:06 β€” πŸ‘ 18    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0

The first draft is for telling yourself the story, revisions are for telling your readers.

16.02.2024 15:37 β€” πŸ‘ 1342    πŸ” 411    πŸ’¬ 33    πŸ“Œ 32
A white pittie on a walk, looking over her shoulder at the camera and licking her nose

A white pittie on a walk, looking over her shoulder at the camera and licking her nose

Hi from one Ruby to another!

09.02.2024 05:26 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Causation in neuroscience: keeping mechanism meaningful - Nature Reviews Neuroscience β€˜Mechanism’ is a frequently used causal concept in neuroscience but can have different meanings that are often not specified. In this Review, Ross and Bassett explore these different meanings and ...

Excited to share a new paper w Dani Bassett on "Causation in neuroscience: keeping mechanism meaningful" in Nature Reviews Neuroscience

We explore different meanings of mechanism in the field, the challenges this presents & how to move forward. 🧠

www.nature.com/articles/s41...

12.01.2024 15:49 β€” πŸ‘ 142    πŸ” 57    πŸ’¬ 10    πŸ“Œ 3

Thanks Dr. Bangasser! It’s been fun getting to cross paths with you on the conference circuit this past year! Hope your 2024 is off to a great start ☺️

11.01.2024 04:01 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Had my final residency interview today and am just so excited to be one small step closer to becoming a psychiatrist physician-scientist! Now back to the wards... #medsky #womeninstem #neuroskyence #addictionsci

11.01.2024 03:06 β€” πŸ‘ 24    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0

New year, new preprint! Cued invigoration of reward seeking promotes sustained population coding in the BLA, which is disrupted by OFC inactivation. Consistent with the notion that BLA represents motivational states.

02.01.2024 15:01 β€” πŸ‘ 18    πŸ” 5    πŸ’¬ 1    πŸ“Œ 2
Screenshot of the first page of the article "The risk of opioid use disorder among women undergoing obstetric-related procedures: Results from the Cerner Real-World Database" published in DADR.

Screenshot of the first page of the article "The risk of opioid use disorder among women undergoing obstetric-related procedures: Results from the Cerner Real-World Database" published in DADR.

Our latest pub delves into the complex link between obstetric procedures OUD in women, highlighting how some procedures (e.g., ectopic pregnancy, cesarean) have a higher risk for OUD than others (e.g., vaginal delivery). bit.ly/OUDandObstet...

02.01.2024 16:44 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

#Benzodiazepines: It is complicated.
#MedSky πŸ§ͺ

jamanetwork.com/journals/jam...

29.12.2023 16:26 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Proud of myself for getting two manuscripts submitted just under the 2023 wire! Stay tuned for some cool πŸ§ͺ🩺🧠 stuff coming out in 2024! #medsky #neuroskyence #addictionsci

29.12.2023 05:49 β€” πŸ‘ 10    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Flyer is on a yellow grid background. Text at the top aligned in the middle says, SURF Paner. Under this text says, Summer Undergraduate Research Fellowship Info Session. On the bottom left is a picture of participants at a Black In Neuro professional development event. Text over the picture says β€œJoin Us” in a yellow heptadecagon shape. Icons of a calendar, clock, and location symbol are vertically aligned in the middle. To the right is a blue bubble that says, January 12 2024. Under this is a blue bubble that says, 1:00-2:15 PM ET. Lastly is a blue bubble under that says, Zoom link. At the bottom of the flyer is a black arrow pointing to www.blackinneuro.com

Flyer is on a yellow grid background. Text at the top aligned in the middle says, SURF Paner. Under this text says, Summer Undergraduate Research Fellowship Info Session. On the bottom left is a picture of participants at a Black In Neuro professional development event. Text over the picture says β€œJoin Us” in a yellow heptadecagon shape. Icons of a calendar, clock, and location symbol are vertically aligned in the middle. To the right is a blue bubble that says, January 12 2024. Under this is a blue bubble that says, 1:00-2:15 PM ET. Lastly is a blue bubble under that says, Zoom link. At the bottom of the flyer is a black arrow pointing to www.blackinneuro.com

Summer Undergraduate Research Fellowship (SURF) are invaluable opportunities for undergraduates to gain research experience. Join Black In Neuro on Friday, Jan. 12, 2024 at 1 PM ET for an information session with universities on the SURF application process. Register now! t.co/MuYLHgnG85 🟦🧠 πŸ§ͺ

26.12.2023 17:37 β€” πŸ‘ 31    πŸ” 32    πŸ’¬ 0    πŸ“Œ 0
A white dog has her head buried in a red gift bag with Merry Christmas written on it

A white dog has her head buried in a red gift bag with Merry Christmas written on it

Merry Christmas ya filthy animals

26.12.2023 03:24 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@sclevis is following 20 prominent accounts