Isabelle Dupin

The efficiency of EURO 6d car particulate filters is compromised by atmospheric aging: In vitro toxicity of gasoline car exhaust Atmospheric processing substantially toxifies tailpipe emissions from a EURO 6d gasoline car with a particulate filter.

Vehicle emission standards must also account for atmospheric transformation to protect human health. Our new study shows that photochemical aging of EURO6d gasoline car emissions leads to an increase toxicity on human lung cells compared to fresh tailpipe emissions.
www.science.org/doi/10.1126/...

An integrated transcriptomic cell atlas of human endoderm-derived organoids - Nature Genetics The human endoderm-derived organoid cell atlas (HEOCA) presents an integrative analysis of single-cell transcriptomes across different conditions, sources and protocols. It compares cell types and sta...

Integrated Organoid Atlas benchmarks new protocols, even more impressive as a Highly Variable Cohort for comparison against perturbation and disease models: nature.com/articles/s41... Lead by @quanxu.bsky.social, in collaboration with Lennard Halle and @fabiantheis.bsky.social

Avis aux amatrices et amateurs de jolis modèles !

More than happy to have been awarded an #ERCCoG grant for my KINTSUGI project ✨! We will be studying mechanisms of lung resilience to atmospheric pollution.
I cannot thank enough all the people who have helped to build the project, the @univbordeaux.bsky.social, the IUF and @inserm.bsky.social🙏.

L’écriture inclusive par-delà le point médian La langue inclusive est l’objet de vives polémiques, mais aussi de travaux scientifiques qui montrent que son usage s’avère efficace pour réduire certains stéréotypes induits par l’usage sy...

"L'écriture inclusive par-delà le point médian" par @lauredasinieres.bsky.social

📣 Seeking for a postdoctoral scientist

To work with Bertrand Simon and me, on Tomographic Diffractive #Microscopy and cylindrical #organoids

🔬 🧫 🧑‍🔬

In @univbordeaux.bsky.social @cnrs.bsky.social IOGS LP2N

Please, write to Bertrand and myself for further information

Fibroblast-induced mammary epithelial branching depends on fibroblast contractility Epithelial branching morphogenesis is an essential process in living organisms, creating organ-specific epithelial shapes. This study uses time-lapse imaging of fibroblast co-cultures with epithelial ...

Very nice paper unravelling the key role of mesenchymal cells to shape epithelial layers in #organoids:
journals.plos.org/plosbiology/...
Direct contact is required, it is not only about diffusible factors.