MAGIC Evidence Ecosystem Foundation

At MAGIC, transformation doesn’t come from a single innovation — it comes from innovation + connection.

🔹 MAGICapp: digital infrastructure for living guidance
🔹 Turning evidence into action
🔹 Making sure guidance is used, not just published

📅 See MAGICapp in action → wkf.ms/3W17lBN

Come hear @leticiakawano.bsky.social share her 2️⃣ favorite features in #MAGICapp 💥
Leticia is a guideline developer who first used MAGICapp as Clinical Chair of the WHO guideline on COVID-19, & later as a methodologist with the BMJ Rapid Recs,

book 🗓️ a demo here: forms.monday.com/forms/baaf06...

YouTube video by MAGICapp 🔍 What Makes MAGICapp Different?

🔎 Discover with Luz Angela Torres López how #MAGICapp transforms clinical practice guideline #CPG development.

Because “one small update taking too much energy” should not be the norm.

YouTube link: youtu.be/2hI_R_T8Zds?...

Wanna check out? 🗓️ Book a demo: forms.monday.com/forms/baaf06...

💥 Still managing guidelines in Word, email, and endless folders? There’s a better way 🫶
#MAGICapp brings structure, collaboration, and easy updates into one secure digital workspace—built with and for guideline developers.
Wanna check? Book a demo: forms.monday.com/forms/baaf06...

5 problems in guideline development — solved with #MAGICapp 😎
✅ Simpler workflow
✅ Real-time collaboration
✅ Always up to date

🔗 Book a demo: forms.monday.com/forms/baaf06...
@thomasagoritsas.bsky.social @chrischampion.bsky.social

5 problems in guideline development — solved with #MAGICapp 😎
✅ Simpler workflow
✅ Real-time collaboration
✅ Always up to date

🔗 Book a demo: forms.monday.com/forms/baaf06...
@thomasagoritsas.bsky.social @chrischampion.bsky.social

Prof. Gordon Guyatt on Why We Built MAGICapp: The Future of Evidence-Based Guidelines “MAGICapp provides a brilliant way to use a structured process to develop an optimal guideline using EBM principles.” — Prof. Gordon Guyatt As one of the founders of evidence-based medicine and MAGICapp, Gordon knows what it takes to make guidance usable — and trustworthy. In this short video, he shares why traditional guidelines often fall short… and how MAGICapp is helping guideline developers and clinicians bring evidence to life. ✅ Structured ✅ Transparent ✅ Layered for different users ✅ Built to support shared decisions 📲 Watch now to hear from one of the field’s most respected voices.

🚀Why is #MAGICapp the go-to platform for guideline development?

In this video, @guyattgh.bsky.social explains how its layered format, structured design, and #EBM foundation make it the optimal solution.

Book a demo at forms.monday.com/forms/baaf06...

#Guidelines #EBM #DigitalHealth

Strategic meetings beteeen MAGIC and WHO to support their clinical practice guidelines
@magicevidence.bsky.social @chrischampion.bsky.social

Operationalizing trustworthy #AI for #GRADE:
JUDGE turns tacit rating-down into 25 teachable prompts.
SMART-GRADE uses #LLMs + human-in-the-loop for traceable summaries.
Next: expand use cases + benchmarks with guideline panels. #GIN2025
@thomasagoritsas.bsky.social @guyattgh.bsky.social

Meeting long-known friends and colleagues Yuqing MadisonZhang and Pablo Alonso #GIN2025 conference in Geneva @magicevidence.bsky.social @gincomms.bsky.social

Wonderful presentation Prashanti! Thanks for all your beautiful work!

Privileged time and interactions with the one and only Gordon Guyatt at #GIN2025 in Geneva, with gratitude for the work and friendship 🙏
@magicevidence.bsky.social @guyattgh.bsky.social

Don’t miss Lyuba’s session at #GIN2025 🎤
“Technological innovation to facilitate guideline adaptation”
📍 Thursday, Office O, 1:35 pm

Powered by #MAGICapp 😎
@thomasagoritsas.bsky.social @lyubovlytvyn.bsky.social

Coming up at #GIN2025 (Thursday 1h35pm room E): Prashanti Eachempati will present 2 big steps for #AI + GRADE 🚀
👉 JUDGE – 25 questions to justify rating down certainty
👉 SMART-GRADE – our LLM-powered tool to automate GRADE

Led by MAGIC with McMaster HEI . Come stop by!
@thomasagoritsas.bsky.social

Low dose aspirin (160mg/d) reduced recurrence in people with colon cancer and PI3K mutations. Emblematic of precision, individualized medicine since the data for aspirin across all colon cancer has been mixed.
www.nejm.org/doi/full/10....

@guyattgh.bsky.social on the core GRADE approach (BMJ) at #GIN2025
Simplifying GRADE is key to wider use—making it practical and accessible without compromising rigor.
At MAGIC, we see this balance as essential for evidence-based decisions that truly reach practice.
@thomasagoritsas.bsky.social

MAGIC at BE-SAFE in Warsaw 🇵🇱
Our colleagues @thomasagoritsas.bsky.social , Valerie & Sumanth joined the 4th #BESAFE Consortium Meeting, sharing updates and working on deprescribing #benzodiazepines guidelines.

besafe-horizon.eu/en/home

YouTube video by MAGICapp MAGICapp: The Future of Guideline Development Is Here

👩‍⚕️📊 New to MAGICapp?
Here’s a 1-minute intro to what it is and why it matters.

youtu.be/LjGTG2NptEc?...

From evidence to action:
🎥 Watch now: youtu.be/LjGTG2NptEc

#MAGICapp #EvidenceEcosystem #LivingGuidelines

🚀 Getting Started with the MAGICapp Text Editor

Discover how to edit, collaborate, and customize directly in MAGICapp.
Watch our new tutorial and learn the essentials to get you started today.

🎥 Watch here: youtu.be/yRoT1fi2R6E?...

#MAGICapp #EvidenceEcosystem #Guidelines #Collaboration

Prognostic models for cardiovascular and kidney outcomes in people with type 2 diabetes: living systematic review and meta-analysis of observational studies Objective To summarise available evidence regarding the performance metrics of validated prognostic models on cardiovascular and kidney outcomes in adults with type 2 diabetes mellitus.Design Living s...

Hot off the press: living SR/MA of prognostic models in #T2D

🔑 RECODe shows acceptable performance for CV + kidney outcomes
⚠️ UKPDS-OM2 more variable
🌍 Part of MAGIC’s work on the evidence ecosystem to strengthen risk stratification & CPG development in #T2D

👉 bmjmedicine.bmj.com/content/4/1/...

Read the publications here:

Living clinical practice guideline (The BMJ): pubmed.ncbi.nlm.nih.gov/40813129/

Living SR + network meta-analysis (The BMJ): pubmed.ncbi.nlm.nih.gov/40813122/

Living SR of prognostic models (BMJ Medicine): pubmed.ncbi.nlm.nih.gov/40832127/

MAGIC is helping reshape diabetes care. 🚀
Together with The BMJ, we’ve just published 3 new living evidence papers on medicines for #T2Dtype:

1️⃣ Living clinical practice guideline
2️⃣ Living SR/NMA
3️⃣ Living SR on prognosis
+

Reporting Guideline for Chatbot Health Advice Studies This Special Communication provides reporting recommendations for studies evaluating the performance of generative artificial intelligence (AI)–driven chatbots when summarizing clinical evidence and p...

jamanetwork.com/journals/jam...

academic.oup.com/bjs/article/...

www.annfammed.org/content/earl...

At MAGIC we are proud to have contributed to CHART guidelines. Our leadership, comprising #PerVandvik, @guyattgh.bsky.social & @thomasagoritsas.bsky.social , was part of this work, aiming at continually enhancing the #evidenceecosystem, grounded in methodological rigor, away from hype and noise +

Serendipity in Veitastrond 🇳🇴 Valley: Two MAGIC colleagues met by chance on a midsummer bike ride, sharing lunch and inspiration amid Norway’s glaciers. Collaboration travels everywhere: next gathering at Vila Viten next week!
 
#Norway #MAGICevidence

🇨🇳 #MAGICevidence 倡导一个互联、协作且高效的证据生态系统，旨在减少研究浪费并最大化健康成果。MAGIC很荣幸能与全球伙伴携手共创🌎

🇬🇧 #MAGICevidence champions a connected, collaborative, and efficient evidence ecosystem that reduces research waste and maximises health outcomes. MAGIC is proud to work with partners all over the world 🌎

🇪🇸 #MAGICevidence promueve un ecosistema de evidencia conectado, colaborativo y eficiente que minimiza el desperdicio en investigación y optimiza los resultados en salud. MAGIC se enorgullece de colaborar con aliados de todo el mundo 🌎

Comparative effectiveness of interventions to facilitate deprescription of benzodiazepines and other sedative hypnotics: systematic review and meta-analysis Objective To review evidence from randomised trials assessing the effectiveness of strategies to deprescribe benzodiazepines and closely related sedative hypnotics (BSH). Design Systematic review and...

The BE-SAFE project is moving deprescription of benzodiazepines & sedative-hypnotics (BSHs) forward 💊✨

A SR/MA of 49 trials (just out in BMJ!) lays the foundation for trustworthy guidance on BSH deprescription
👉 www.bmj.com/content/389/...

@thomasagoritsas.bsky.social

Prof. @guyattgh.bsky.social, one of the founders of Evidence-Based Medicine #EBM, explains why #MAGICapp is a breakthrough for guideline development: multilayered, user-friendly, and built for trustworthy, living guidelines
Ping @thomasagoritsas.bsky.social @chrischampion.bsky.social

Clinical guidelines only work when they reach frontline care 💥

MAGIC is supporting MARC‑SE Africa by powering dynamically‑updated, evidence-based malaria treatment guidelines and graphic evidence summaries via MAGICapp – directly at the point of care

www.marcse-africa.org