Seth m.l.

Scientists Discover How To “Switch Off” Cancer Genes for Good A new study shows that targeting key epigenetic proteins may permanently switch off cancer genes. Scientists at Monash University, working with Harvard University, report they have found a way to perm...

Oh, my goodness, this is a huge breakthrough in cancer research. This is another example of why it is crucially important to fund basic scientific research.
Scientists Discover How To “Switch Off” Cancer Genes for Good share.google/WFhMJP5m3AK4...

We'll tackle this issue again in 80-90 years.

It sure seems like when we have our basic needs met, and don't have to hustle to survive, humans will almost always choose to create art.

And there is a lot of evidence that when a society decides to honor and promote art and artists, everyone who lives there is measurably happier.

Everybody’s talking about the destruction of consumer electronics and that’s bad, but basically everything in modern life has a computer in it. Hospitals, airports, transportation, shipping, medical devices, farm equipment, and point of sale terminals had a good run

you're correct about sonic youth - ranaldo's work after sonic youth kinda proves it. but also steve shelley's an underrated drummer. dude somehow merged the drumming style of the beatles with joy division and made it work, and that beat allowed the guitar wankery of sonic youth to feel tethered

Telling people to vote for Newsom on Bluesky in February of 2026 feels like posting on Facebook that they can’t use your likeness or content

oh my god. The rest of the world is laughing at us once more. Now the President is going to babble about chemtrails.

my spouse does a thing! i'm immensely proud of her -- a somber meditation of castes and exclusion, of death and celebration, of threat trans existence have against a moribund status quo.

the cat, as you can tell, is helping.

2 of 2 neat updates. Also got my contributor copies of The Society of Vegetarian Cannibals. It's uber fancy and shiny as a hardcover. Apart from the signature page, the limited editions have gnarly roots wandering over the inner sleeve. Get it here: pspublishing.co.uk/the-society-...

"Bad thing existed before I made it easier to do bad thing" isn't the argument you think it is.

True, but broad dreams like "get published" or even "sell a lot of books" aren't dead.

But, "Write articles and short stories for slick magazines" or "see my annual paperback release in every drug store" are dead.

this song is so great

Good. Keep going

The mass market paperback is vanishing The mass market paperback — born in 1935, boomed after WWII — is vanishing from airports, drugstores, and groceries.

For those of you who were keeping up with the mass market mess, here is a more informative article.

Trade paperbacks cost only 30c more to make and are priced $18-20 now, where mass market paperbacks didn't sell at $12. So... there's your answer. It's about margins.

boingboing.net/2026/02/10/t...

The rest is scary enough, but buried in there is the insinuation that Canadian citizens are secretly yearning for American products but the tyrannical Canadian government is keeping it from them instead of, well, Canadians are disgusted with the US and are rightly voting with their pocketbooks.

Remember, kids, the "F" is February stands for FUCK ICE.

scratch a libertarian and a monarchist bleeds

you right now every time you hear the word 'Brontë'

*I get it that no machine can tell Serbs and Croats apart, but what gives with the "Beat Saber" videogame alignment

bluesky-map.theo.io

I'm planning on not leaving my house today, save *maybe* to grab a burrito from the taqueria around the corner. just me and my massive backlog of books.

they can have today, I have the city for the other 364 days.

attn. @countjackula.bsky.social - the artwork on this Transformers comic is mind-blowing

Paul W.S. Anderson is in a small group of directors (with David Twohy) who absolutely CAN make 'so bad it's good' movies but usually just make bad movies.

If you like fun shlock, this is why we need reviewers who dig the same to help the rest of us cut the wheat from the chaff

It's #BandcampFriday and Legendary Pink Dots have some releases to check out!

😂😂😂

may all of our trolls leave quietly today

A song you love in a genre you dislike

The example of the Washington Post is worth considering the next time you feel the urge to say "I wish some nice billionaire would just GIVE me something or being my patron or float my business!"

Sir Ian McKellen performing a monologue from Shakespeare’s Sir Thomas More on the Stephen Colbert show. Never have I heard this monologue performed with such a keen sense of prescience. Nor have I ever been in this exact historical moment.TY Sir Ian, for reaching us once again.
#Pinks #ProudBlue

Washington Post, 2017: Democracy dies in darkness!

Washington Post, 2026: [Emperor Palpatine voice] Democracy dies in darkness.

good god, that cover is amazing.

I am judging a book by it's cover and feel no regrets.