Shreyank Tripathi

If the cars is Nissan: it is neph fellow or academic nephrologist, if Tesla : private neph, and if Porsche it is plumber

Have you all been using it in out pt settings and if so, does the pt needs monthly hosp admins?

Did not last long .

Dialysis pts on Medicare also have copayments. Providers&LDO waive that as no one pays. They survive on 80%. This is will be same for Medicaid. This will not hurt the pts: this is against providers and LDO.

www.cbsnews.com/dialysis/

Lorundrostat Efficacy and Safety in Patients with Uncontrolled Hypertension | NEJM Aldosterone dysregulation contributes to hypertension. Lorundrostat is an aldosterone synthase inhibitor, but data on its efficacy and safety in patients with hypertension are limited. In this mult...

The ASIs have arrived

www.nejm.org/doi/full/10....

Aldosterone synthase inhibitors - first one to finish the phase 3 line

#Lorundrostat #Hypertension

In all fairness, your average value based care program is based on equally questionable formulas.

Figure 1 Changes in UACR with retatrutide versus placebo. The figure shows the percent change from baseline in UACR. Data are least-squares means with error bars showing standard errors derived from the MMRM of the efficacy analysis set. Percent change from baseline in UACR over time from the MMRM analysis for all participants in the (A) T2D study and (B) obesity efficacy population and among participants with baseline UACR of ≥30 mg/g in the (C) T2D and (D) obesity trials. Abbreviations: MMRM= mixed model repeated measures. RETA=retatrutide. SE=standard error. T2D=type 2 diabetes. UACR=urine albumin-to-creatinine ratio.

Retatrutide (GLP, GIP, Glucagon receptor agonist) and albuminuria and GFR changes from phase 2 trial now in @kireports.bsky.social

Two Ph2 trials, one in T2DM and another in Obesity with about N ~ 300 each

uACR reduced in both RCTs (A, B)
Much more pronounced when baseline > 30 mg/g (C, D)
1/

Could the shingles vaccine help to prevent dementia? Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia — but it’s not yet clear how.

www.nature.com/articles/d41...

"Large-scale analyses of electronic health data suggest that the herpes zoster vaccine could protect against dementia..."

www.kireports.org/cms/10.1016/...

Flozinate them all!
#transplant #sglt2

Phosphorus Content of Several Plant-Based Yogurts In people with chronic kidney disease (CKD), hyperphosphatemia is a risk factor for mortality. Though unproven, dietary phosphorus control is considered essential in CKD. Although dietary and serum ph...

www.jrnjournal.org/article/S105...

Low-PPR foods are important for CKD patients. Siggi's Coconut Mixed Berries had the lowest PPR, making it potentially the most desirable for CKD pt.Delicious Coconut Strawberry had the highest PPR, highlighting the importance of product selection for pt with CKD.

Association Between Cardiorespiratory Fitness and Trend of Age-Related Rise in Arterial Stiffness in Individuals With and Without Hypertension or Diabetes AbstractBACKGROUND. This study aimed to investigate whether higher cardiorespiratory fitness (CRF) can modify the trend of age-related rise in arterial sti

academic.oup.com/ajh/article-...

The higher CRF levels may mitigate the trend of age-related rise in arterial stiffness in individuals with and without HTN or diabetes. However, this attenuating trend appears more pronounced in individuals without HTN or diabetes.

There is a huge and vital Indian Nephrology community on social media but they have largely not made the jump to Bluesky. Please support Arvind and show him how good #NephSky is so he can encourage other Indians to migrate over. #WeAreBetterTogether

I have been getting a ton of denials for Calcitriol for 2 PTH and the payers are demanding Peer to peer for that .

Tacrolimus for kidney transplant patients only $30.36 for 5mg 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky

Cellcept for kidney transplant patients only $9.66 for 30 day supply at www.costplusdrugs.com/medications/... #PharmaSky #RenalSky

Private equity reduces patient care while enriching investors, Senate report finds The bipartisan investigation of hospital systems purchased by Apollo Global Management and Leonard Green & Partners reinforced the findings of past academic research.

Duhhh. Who would knew???

www.nbcnews.com/news/investi...

Our hospital system ( the largest in US) has added UA without reflex to culture in the order set.

Russia 🤦🏻‍♂️
TOPCAT funny business
evidence.nejm.org/doi/full/10....

Patrick Freyne: I am becoming a demotivational speaker – let’s all have an averagely productive December I keep meeting people who are extremely burned out. I meet them so often that I’m beginning to think burnout is something that exists by design

Goals and dreams are great... as long as they don't come at the cost of our mental and physical health.

Being comfortable is ok. Being good enough is ok.
"It's fine if you don't do that."

www.irishtimes.com/life-style/p...

I am in the same boat. Except in cases of oliguric AKI, I do find it useful.

#askrenal Pt with multiple cysts on the kidney ( appears to be ADPKD) but has ADTKD-UMOD ( confirmed genetic testing), non nephrotic proteinuria , progressive CKD: how would you treat this pt : RAASi and what else

Shrey Tripathi , Richmond, VA. #nephJC
Lots of conflicts in renal world about this issue and lots of interest in tonight’s JC. But no COI.

Welcome everyone to #NephJC!

Tonight, we will take a ROAD less, or maybe more often traveled lately. BPROAD tests the lower limits of BP, potential benefits, and harms in patients with diabetes

www.nejm.org/doi/ful...

1/9
🤔 Why doesn't an elevated BUN lead to extreme thirst? If increased serum osmolarity compels us to seek water, uremia should be a significant driver of this craving.

And yet, it isn't.

Let's examine why.

CSN AGM logo

The #CSNAGM will be in Vancouver in May 2025

Only a couple of days left to submit your abstract: catalyst.omnipress.com#event-home/c...!

“The first method for estimating the intelligence of a ruler is to look at the men he has around him.”

― Niccolò Machiavelli

Anyway to bookmark a post?

Great!