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@bastianengel.bsky.social

MD, GI & Hepatology, Hannover Medical School. Interested in Liver Transplantation and Autoimmune Liver Disease.

118 Followers  |  243 Following  |  15 Posts  |  Joined: 23.11.2024  |  2.2384

Latest posts by bastianengel.bsky.social on Bluesky

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How Atlantic islands are proving tourism can help the ocean From underwater archaeology to whale-watching tours led by actual scientists, Europeโ€™s Atlantic islands demonstrate how tourism can protect rather than destroy natural and cultural heritage of the oce...

๐Ÿ”ฅ non-medical
๐ŸŒŽ planetary health is critical

Check out this video by naturalists about sustainable tourism and ocean protection on the Azores.

Scientist-led, EU-funded ๐Ÿ‡ช๐Ÿ‡บ

Happy to have joined this year. Check it out.
support them if you visit the Azores.

www.euronews.com/green/2025/0...

30.07.2025 06:14 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model npj Digital Medicine - Automating liver biopsy segmentation with a robust, open-source tool for pathology research: the HOTSPoT model

๐Ÿ”ฅ Looking for automated segmentation of liver histopathology? Donโ€˜t look further.

Hotspot Model got you covered.

Happy to have contributed.

Great work @aleger87.bsky.social and team!

rdcu.be/ew7qh

22.07.2025 06:04 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Redirecting

๐Ÿ”ฅ Publication alert from us!

๐Ÿงฌ Distinct molecular profiles of AMR and TCMR after #liver #transplant
๐Ÿ“ˆ AMR associates w/ high rate of graft #cirrhosis
๐Ÿงช IFN mediates TCMR, TNF mediates AMR as in other SOT

doi.org/10.1016/j.jh...

#openaccess @jhepatology.bsky.social
#liversky @easlnews.bsky.social

17.07.2025 14:06 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Redirecting

doi.org/10.1016/j.jh...

17.07.2025 14:04 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ”ฅ Publication alert from our group!

๐Ÿงฌ Distinct molecular profiles of AMR and TCMR after #liver #transplant
๐Ÿ“ˆ AMR associates w/ high rates of graft #cirrhosis
๐Ÿงช IFN mediates TCMR and TNF mediates AMR as in other solid organs

#openaccess @jhepatology.bsky.social
#liversky @easlnews.bsky.social

15.07.2025 17:03 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Thank you for sharing! It was a pleasure working on this, together with @twittlabs.bsky.social , @jnkt.bsky.social and many others...

30.06.2025 13:49 โ€” ๐Ÿ‘ 6    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Whom to treat in #AIH #cirrhosis with decompensation?

๐Ÿ’Š Steroids if:
๐Ÿง  encephalopathy equal or less than grade 2
๐Ÿ“ˆ MELD-Na 28 or below

๐Ÿš’If patients with AIH do not meet this criteria #transplant might be the better option.

#liversky @easlnews.bsky.social

authors.elsevier.com/c/1l6Pu5UiFS...

19.05.2025 07:28 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

๐Ÿ†•CPG in pressโ•

EASL Clinical Practice Guidelines on extrahepatic abdominal surgery in patients with cirrhosis and advanced chronic liver disease

Find it here๐Ÿ‘‰https://bit.ly/3GM9EEB

#LiverSky
@easlnews.bsky.social

10.05.2025 06:05 โ€” ๐Ÿ‘ 9    ๐Ÿ” 7    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial Nivolumab plus ipilimumab showed a significant overall survival benefit versus lenvatinib or sorafenib and manageable safety in patients with previously untreated unresectable hepatocellular carcinoma...

New @thelancet.bsky.social - Nivolumab plus ipilimumab versus lenvatinib or sorafenib as first-line treatment for unresectable hepatocellular carcinoma (CheckMate 9DW): an open-label, randomised, phase 3 trial

www.thelancet.com/journals/lan...

#Liversky #Oncsky #Medsky #EASL2025

08.05.2025 13:01 โ€” ๐Ÿ‘ 2    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Canโ€™t wait for #EASL2025! @easlnews.bsky.social

Join Colm Oโ€™Rourke and me, on Friday for a session weโ€™ve designed and are thrilled to chair:
โ€œDoโ€™s and Donโ€™ts in Liver Transcriptomicsโ€
Arnold Room | 3โ€“4PM

Come for insights, tips & tricks from Neil Henderson, Johan Ankarklev, & Simon Cockell!

07.05.2025 10:15 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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๐Ÿ†•CPGโ•

EASL Clinical Practice Guidelines on TIPS

โœ…Addresses all aspects of #TIPS in patients with #cirrhosis

Full text here: bit.ly/4hZuMUK

#LiverSky
@easlnews.bsky.social

03.04.2025 07:56 โ€” ๐Ÿ‘ 13    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
How is hepatitis D treated?
YouTube video by TherVacB - Awareness & Insights on Hepatitis B How is hepatitis D treated?

๐Ÿค”How is #hepD treated? Why is this relevant for #hepB patients? ๐Ÿ‡ฉ๐Ÿ‡ช๐Ÿ—บ๏ธ
๐ŸŽž๏ธWatch insights from #internists ๐Ÿฅผ#HelenieKefalakes
#LisaSandmann in our fresh release youtu.be/d7dV2G6tMXA
#hepatitisawareness๐Ÿ“บwith experts answering key #HBV #HDV questions
#MHH #B_Aware #D-SOLVE #LiverHealth #LiverSky #HepSky

02.04.2025 08:52 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

โœฎ Kather Lab is hiring PostDocs & Software Engineers!

โ˜ž Strong Python & PyTorch skills, GitHub experience, and interest in LLMs & computational pathology required. โ€จโ€จ

Apply hereโ•ฐ( อกยฐ อœส– อกยฐ )ใคโ”€โ”€โ˜†*ใƒป๏พŸ: bit.ly/42nY62u

31.03.2025 14:41 โ€” ๐Ÿ‘ 10    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Happy to share our latest paper in @ai.nejm.org, led by Isabella Wiest: "Deidentifying Medical Documents with Local, Privacy-Preserving Large Language Models: The LLM-Anonymizer" ai.nejm.org/doi/full/10....
You can use our open source tool with local LLMs to robustly de-identify medical documents.

27.03.2025 18:32 โ€” ๐Ÿ‘ 9    ๐Ÿ” 5    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Spicy!

Adding lasix to the management of hepatorenal syndrome might be ok if you bump the MAP with pressors

@juancarlosqvelez.bsky.social

doi.org/10.1016/j.ek...
#nephsky #liversky

04.03.2025 00:08 โ€” ๐Ÿ‘ 26    ๐Ÿ” 9    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Seltene Lebererkrankungen (LeiSe LebEr) - DGVS - Deutsche Gesellschaft fรผr Gastroenterologie, Verdauungs- und Stoffwechselkrankheiten

Find the latest evidence on #autoimmune #liver diseases (in German, but #AI will help to translate) in which we summarize the latest evidence, finally on the highest level achievable for guidelines.

This highlights the progress in the #AILD field in the last years.

www.dgvs.de/leitlinien/l...

21.02.2025 10:36 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@joostphdrenth.bsky.social @easlnews.bsky.social @aleger87.bsky.social #LiverSky

20.02.2025 06:48 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Health-related quality of life is impaired in people with... : Hepatology ted outcome measures. Methods: Adult AIH patients diagnosed at 12 European centers were enrolled in this prospective, cross-sectional study from July 2020-June 2023. HRQoL was assessed using the Ph...

Fresh from #Hepatology, cross-sectional multicenter study on Quality of Life in #AIH.

๐Ÿ‘ 882 patients, 178 controls across Europe #ERN
๐Ÿ‘Ž QoL impaired mainly by physical complaints
๐Ÿ“ˆ QoL correlated w/ depression/anxiety
๐Ÿ’Š remission associated w/ improved symptoms

doi.org/10.1097/HEP.0000000000001271

20.02.2025 06:47 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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In today's #readoftheweek๐Ÿ“š learn about the ALNE model and how it generates quantitative and accurate differential diagnosis between cases with AIH or PBC.

Read here this JHEP Reports article: www.jhep-reports.eu/article/S258...

@jhepatology.bsky.social #LiverSky

19.02.2025 15:38 โ€” ๐Ÿ‘ 7    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Happy to have contributed to this project led by @aleger87.bsky.social

๐Ÿค– ML-based detection of AIH and PBC from H&E stained slides
๐Ÿ’ฅ solid performance with heterogenous staining/scanning
๐Ÿ˜ณ no annotation needed

More to come and looking forward to it! @jnkt.bsky.social #liversky

20.02.2025 06:06 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@jhep-reports.bsky.social @easlnews.bsky.social @jhepatology.bsky.social

18.02.2025 13:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Redirecting

๐Ÿ”ฅ off the press.
Multicenter study using proteomic signatures to identify biomarker candidates in acute liver failure led by Pavel Strnad from Aachen.

๐Ÿจ disriminate APAP from non-APAP
๐Ÿ“‰ predict transplant-free survival from ๐Ÿฉธ
๐Ÿงฎ outperform MELD and AFLSG-PI

Great work ๐Ÿ‘ doi.org/10.1016/j.jh...

18.02.2025 13:43 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

The autoimmune hepatitis field is quite unique in the way clinicians and researchers on AIH are connected personally worldwide. Optimal starting point for generalizable prediction algorithms ...

18.02.2025 13:30 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@aleger87.bsky.social @janclusmann.bsky.social @jhep-reports.bsky.social @joostphdrenth.bsky.social

18.02.2025 13:21 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

@easlnews.bsky.social @jhepatology.bsky.social

18.02.2025 13:19 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Quo vadis autoimmune hepatitis? - Summary of the 5th international autoimmune hepatitis group research workshop 2024 Autoimmune hepatitis (AIH) is a rare chronic liver disease with an increasing incidence in many countries. Chronic autoimmune responses against the liver can cause hepatic and extrahepatic symptoms, d...

Starting on Bluesky with our summary about most pressing issues in #AIH

๐Ÿค– Employing AI for research and patient information
๐Ÿงฌ Unveil pathogenesis by using single cell techniques
๐Ÿงช new biomarkers, validate candidates
๐Ÿ“Š New clinical trials, harmonize outcome sets

www.jhep-reports.eu/article/S258...

18.02.2025 13:19 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
This is figure 2 from โ€œA year above 1.5โ€‰ยฐC signals that Earth is most probably within the 20-year period that will reach the Paris Agreement limit.โ€ It shows strong warming trends place the first 1.5โ€‰ยฐC year within the 1.5โ€‰ยฐC 20-year period.

This is figure 2 from โ€œA year above 1.5โ€‰ยฐC signals that Earth is most probably within the 20-year period that will reach the Paris Agreement limit.โ€ It shows strong warming trends place the first 1.5โ€‰ยฐC year within the 1.5โ€‰ยฐC 20-year period.

Two papers in Nature Climate Change suggest that exceeding 1.5 ยฐC in 2024 may indicate that we have entered a multi-decadal period of 1.5 ยฐC average global warming.
https://go.nature.com/4hR9GYO
https://go.nature.com/3WVdJM1
๐Ÿงช

10.02.2025 20:12 โ€” ๐Ÿ‘ 49    ๐Ÿ” 26    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Thermal ablation vs surgical resection of small colorectal liver metastases (COLLISION trial)

โ€œThe assumption that thermal ablation should be reserved for unresectable colorectal liver mets requires re-evaluationโ€

www.thelancet.com/journals/lan...

#GastroSky #OncSky #MedSky @oncoalert.bsky.social

21.01.2025 08:26 โ€” ๐Ÿ‘ 11    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@bastianengel is following 20 prominent accounts