Vu Tran

We have two Cancer Biology graduate students defending their dissertations next week 🎉 Best wishes to Vu Tran (Bresnick lab) defending on July 21 and Stuart Fogarty (Kenney lab) defending on July 22!

Congratulations to Renee King, PhD (Lambert Lab) for being awarded a prestigious NIH Pathway to Independence Award! mcardle.wisc.edu/2025/07/01/r...

And here it is! Our study in clonal hematopoiesis and Alzheimer’s disease — product of 5 years’ gestation. urldefense.proofpoint.com/v2/url?u=htt...

Dual mechanism of inflammation sensing by the hematopoietic progenitor genome Leukemia predisposition–linked hematopoietic transcription factors mediate inflammation sensing by a progenitor cell genome.

The second part of my thesis work has been published in Science Advances:
www.science.org/doi/10.1126/...

Wishing #mcardlelab graduate student Athena Golfinos-Owens (Dinh lab) all the best as she defends her thesis this week!

Congratulations to #mcardlelab professor Wei Xu for receiving the Vilas Mid-Career Investigator Award! mcardle.wisc.edu/2025/05/09/w...

Register for our 19 May webinar, Meet the Funders. Learn more about funding opportunities from Edward P. EvansMDS Foundation, Alex's Lemonade Stand Foundation and @leukemiaresearch.bsky.social and join the conversation! 👉 www.iseh.org/ISEHWebinars

Best wishes to Cancer Biology graduate student Adeline Ding as she defends her dissertation this week!

Transcription factor networks disproportionately enrich for heritability of blood cell phenotypes Most phenotype-associated genetic variants map to noncoding regulatory regions of the human genome, but their mechanisms remain elusive in most cases. We developed a highly efficient strategy, Perturb...

Delighted to have our Perturb-multiome paper, led by #JorgeMartinRufino and @hemagene.bsky.social from our lab, published today in @science.org. Please check out this powerful approach to decipher gene regulatory networks enriched for genetic variation: www.science.org/doi/10.1126/...

#mcardlelab alum Tim Schedl named a 2024 AAAS Fellow: mcardle.wisc.edu/2025/04/01/t...

Developed by scientists at St. Jude and UW-Madison, Spotiphy achieves both single-cell resolution and genome-wide coverage, advancing insights into diseases like Alzheimer’s and cancer.

Explore its potential: ow.ly/weiP50Vgphv

Tomorrow at 11 am CST: join in person or on Zoom for the latest #cancerbiologyseminar. Sponsored by #mcardlelab. uwmadison.zoom.us/j/96369895715

ISEH is thrilled to announce the recipients of the 2025 Society Awards, which will be presented at the ISEH 54th Annual Scientific Meeting. Read more about each award recipient on www.simplyblood.org

🗳️ Make your voice heard and vote in the 2025-2026 Board of Directors election. The election closes 18 March. You must be an ISEH member to cast a vote ➡️ Learn more: ww.iseh.org/2025Election

The Call for Abstracts for #ISEH2025 🏯 is open! Submit your abstract for opportunities to present your work to some of the most prominent hematology researchers from around the globe. Deadline to submit is 12 May. www.iseh.org/2025Abstracts

Check out our database of 47 POSTDOCTORAL fellowships in cancer/oncology.

For each fellowship, we provide a brief description, link to opportunity, deadline, and eligibility criteria (e.g. citizenship).

Download this database here (Excel file): research.jhu.edu/rdt/funding-...

Good luck!

The developmental clock: where art and science meet Elaine DzierzakDrs. Elaine Dzierzak and Anna Bigas recently edited a special collection for Experimental Hematology entitled “Making blood: mechanisms of early hematopoietic development” [1]. This is ...

What an interesting read...did you know that Developmental Hematopoiesis pioneer Elaine Dzierzak was also an artist? Read on to learn more in a recent issue of Experimental Hematology!

The developmental clock: where art and science meet - Experimental Hematology www.exphem.org/article/S030...

Check out the latest article on malignant hematopoiesis - CBX7 Inhibitors Affect H3K9 Methyltransferase-Regulated Gene Repression in Leukemic Cells www.exphem.org/article/S030...

🚨 Calling all hiring faculty and job-seeking students!🚨 The ISEH 2025 Virtual Career Fair registration is now open. Secure your spot for free on 15 April https://www.iseh.org/CareerFair2025

Transcriptional activation of regenerative hematopoiesis via microenvironmental sensing - Nature Immunology Itkin et al. identify a role for Fli-1 in hematopoietic stem cell activation during regenerative hematopoiesis. They show that Fli-1 coordinates hematopoietic stem cells to stimulate niche-derived Not...

Check out this elegant 🧪publication showing that Fli-1 activity is essential for regenerative 🩸 hematopoiesis from Tomer Itkin and Shanin Rafii. I am delighted to have been included.
@weillcornell.bsky.social @pmresearch-uhn.bsky.social

www.nature.com/articles/s41...

HTBT study section, scheduled for tomorrow (I am a standing member), was just canceled. HTBT reviews grants on hemostasis/thrombosis, red cells, marrow failure, HSPCs, sickle cell and so many other critical topics in medicine. Science delayed is new cures denied and potential lab closures.

Vote for the 2025-2026 Board of Directors! The election closes 18 March. You must be an ISEH member to cast a vote ➡️ Learn more: www.iseh.org/2025Election

Tomorrow at 11 am CST: join in person or on Zoom for the latest #cancerbiologyseminar. Sponsored by #mcardlelab. uwmadison.zoom.us/j/96369895715

Frontiers | The aging hematopoietic stem cell niche: a mini review

Check out our new review on Frontiers in Hematology! www.frontiersin.org/journals/hem...

Methodological Considerations on How to Identify Human Hematopoietic Stem Cells The hematopoietic system is highly regenerative and is organized hierarchically with hematopoietic stem cells (HSCs) sitting at the apex. Despite being some of the most widely studied stem cells, ques...

If you are approaching human hematopoiesis, this is a great resource for preparing your experimental protocols! Congrats to the authors! @isehsociety.bsky.social
#hemesky 🔬🩸

www.exphem.org/article/S030...

The first issue of #ExpHem for 2025 is here, marking the beginning of what promises to be a great year of new science! Don't miss articles in this issue from @charles-debock.bsky.social, Lev Kats, Hitoshi Takizawa, and more! www.exphem.org/issue/S0301-...

Targeting the CD74 signaling axis suppresses inflammation and rescues defective hematopoiesis in RUNX1-familial platelet disorder CD74 signaling drives inflammation and differentiation defects in hematopoietic stem and progenitor cells in RUNX1-familial platelet disorder.

Inflammation plays a key role in RUNX1-FPD pathogenesis. Dr. Anupriya Agarwal & her team at @ohsunews.bsky.social found targeting CD74 signaling, mTOR & JAK1/2 pathways could prevent disease progression. Incredible work by an RRP-EdwardPEvansFdn FIRE grant recipient! www.science.org/doi/10.1126/...

We are hiring 😀

Postdoctoral position – Stem cells, Cancer, and Aging

We study cell fate decision and lineage specification in hematopoietic stem and multipotent progenitor populations to modulate lineage output for therapeutic purpose in diseases and aging contexts.

The first Preprint Watch for 2025 is plentiful: 9 preprints focusing on Acute Myeloid Leukemia, but also spatial fate mapping meets barcoding, how cell fate decisions occur in hematopoietic progenitors, and more! Read now➡️ simplyblood.org

Congrats, Gayathri! So excited for your new journey!