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Josh Lang

@joshlangmd.bsky.social

Professor and Associate Director of Translational Research, GU Medical Oncologist at the University of Wisconsin Carbone Cancer Center. https://langlab.labs.wisc.edu/ #prostatecancer #cancerbiology #biomarkers

335 Followers  |  181 Following  |  53 Posts  |  Joined: 18.11.2024  |  1.7326

Latest posts by joshlangmd.bsky.social on Bluesky

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Restaging w/ #PSMA Imaging in #mCRPC #ProstateCancer: When Seeing More Is Detrimental to Care

Sadly a year later this remains true & the frequency of this is πŸ“ˆ

@ascocancer.bsky.social @ascopost.bsky.social

ascopubs.org/doi/pdf/10.1...

04.08.2025 20:05 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Patient Perspectives on Prior Authorization for Cancer Care This qualitative study characterizes the perspectives of patients with cancer regarding their experience with prior authorization for cancer care.

πŸ—£οΈ"The system is horribly broken & it hurts patients unnecessarily”
πŸ—£οΈ"They wrote me off as a dead man”
Β 
Navigating #priorauth requires tech savvy, an understanding of insurance processes, knowledge of personal rights, & time to engage in the process.
Β 
@ascocancer.bsky.social @astro-org.bsky.social

31.07.2025 15:44 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Shout out to the WSJ journalists who reported on Vought’s impoundment by footnote, causing the White House to walk it back. Impact journalism!!

30.07.2025 04:00 β€” πŸ‘ 2326    πŸ” 580    πŸ’¬ 24    πŸ“Œ 20
Cancer Clear and Simple Podcast Welcome to β€˜Cancer Clear and Simple,’ the podcast dedicated to simplifying cancer. Join us as we discuss the world of cancer, breaking down complex concepts for our listening audience. One of our goal...

Such an honor and so much fun to join the Cancer Clear and Simple @uwhealth.bsky.social Carbone Cancer Center Podcast to discuss liquid biopsies in cancer!

cancer.wisc.edu/community-ou...

25.07.2025 13:11 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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First-ever financial toxicity tumor board aims to change the standard of care Researchers focus on debt as a side effect of cancer, treatment amid cuts to Medicaid, NCI - The Cancer Letter Nearly half of cancer patients and survivors in the United States face medical debt so crushing that it has sparked a relatively new focus within oncology: financial toxicity. To access this subscribe...

"We cure a lot of diseases, & we create a lot of medical debt. It’s a push/pull; right?

The advances that we have within science & medicine are profound. We have people living longer & better. Yet, the cost of treatment is a side effect like any other."

#financialToxicity @cancerletter.com

15.07.2025 18:57 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
THE HEALTH INSURANCE
MAZE
How Cancer Patients Get Lost in the Red Tape of Utilization Management

THE HEALTH INSURANCE MAZE How Cancer Patients Get Lost in the Red Tape of Utilization Management

Key Report Themes
CANCERCATE
Over 80 Years ef Help and Hope
β€’ Prior authorization is widespread and repetitive
β€’ Prior authorization leads to time burdens and care delays
β€’ Coverage stoppages surprise patients and interrupt care
β€’ Insurance problems affect stress, health, finances, and trust
β€’ Self-advocacy barriers include gaps in insurance literacy and system awareness
β€’ Employer-sponsored plans carried highest administrative burdens, followed by Medicare Advantage, then Traditional Medicare

Key Report Themes CANCERCATE Over 80 Years ef Help and Hope β€’ Prior authorization is widespread and repetitive β€’ Prior authorization leads to time burdens and care delays β€’ Coverage stoppages surprise patients and interrupt care β€’ Insurance problems affect stress, health, finances, and trust β€’ Self-advocacy barriers include gaps in insurance literacy and system awareness β€’ Employer-sponsored plans carried highest administrative burdens, followed by Medicare Advantage, then Traditional Medicare

Needed At Least One Prior Authorization for Cancer Treatment, Past 12 Months, by Insurance Type

Needed At Least One Prior Authorization for Cancer Treatment, Past 12 Months, by Insurance Type

"It is a nightmare waking up every day wondering if some people halfway across the country will approve what my doctors have said is my only chance."

πŸ“„ New #PriorAuth in cancer report shows the scope of the problem & the need to #fixpriorAuth @cancercare.bsky.social

www.cancercare.org/redtape

18.06.2025 17:48 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is how it begins...

05.06.2025 22:02 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Review of 2024 – Palaces and Parliament It’s great to start by celebrating still being alive at the end of another year given that, in May 2017, I was told I might only live 2 years! 2024 saw me enter my 8th year post diagnosis having su…

Better late than never I guess! Every year I try to write a review of the year just past, primarily for my grandkids to read when I’m no longer around and here is 2024 finally! runningintocancer.co.uk/2025/05/29/r...

29.05.2025 13:27 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Memorial Day dub

There we go

#MilwaukeeBrewers#BrewersBaseball #MLB

26.05.2025 22:25 β€” πŸ‘ 19    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Grateful to @ascocancer.bsky.social Ed Book πŸ“—@n8pennell.bsky.social for this #MedEd publication

πŸ›£οΈ How to move forward in #EarlyCareer
🚧 Overcoming barriers
βš™οΈ Switching gears
⏰ Making time and space

πŸ”—: ascopubs.org/doi/10.1200/...

@ericroeland.bsky.social
@ryannipp.bsky.social

08.05.2025 08:43 β€” πŸ‘ 11    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
Radiation cystitis!!! Help!!
YouTube video by GU Cast Radiation cystitis!!! Help!!

Special episode of GU Cast from Guy’s Hospital focused on #RadiationCystitis. Unique clinic dedicated to these unfortunate patients learn from Yasmin and Ramesh and team. Some great insights youtu.be/d4A2_swZOHw?...

23.04.2025 08:59 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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US measles total climbs to 800 cases, 10 outbreaks

Latest data on measles in the US. The total number of cases has already reached 800 in the first 4 months of 2025 with 85 hospitalizations and 3 deaths. There were 285 total cases last year. πŸ§ͺ
www.cidrap.umn.edu/measles/us-m...

21.04.2025 02:04 β€” πŸ‘ 70    πŸ” 37    πŸ’¬ 5    πŸ“Œ 8
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Ohio Medicaid got rid of big middlemen. Says it paid pharmacies a lot more β€” and saved $140M β€’ Ohio Capital Journal The Ohio Department of Medicaid department in 2022 gave powerful prescription drug middlemen the boot and created a new system. The result: Fees paid to pharmacies were boosted more than 1,200% while ...

Ohio Medicaid got rid of big middlemen. Says it paid pharmacies a lot more β€” and saved $140M ohiocapitaljournal.com/2025/04/17/o...

17.04.2025 13:29 β€” πŸ‘ 11497    πŸ” 2556    πŸ’¬ 323    πŸ“Œ 136
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What if we screened smarter, not just more?
In BARCODE1, men with high polygenic risk (top 10%) had MRI + biopsyβ€”
40% had prostate cancer.
Over half needed treatment.
Most would’ve been missed by PSA alone.
Genetics is rewriting the rules.
@nejm.org @myesmo.bsky.social @oncoalert.bsky.social

10.04.2025 05:30 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

The act will disenfranchise vets/active/overseas military from voting as well (who often have less access to reams of documents)

LDF Denounces House Passage of SAVE Act, Urges Senate to Reject Bill that Will Disenfranchise Millions of Americans - naacpldf.org/press-release/…

#HellNo #VotesForVets

10.04.2025 18:33 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

We have known for years that uninsured and underinsured patients with cancer have the worst clinical outcomes. Medicaid is the only lifeline for many of these patients to get the care they need. As an oncologist, I have personally seen the harm caused lack of coverage. Our patients deserve better.

10.04.2025 17:34 β€” πŸ‘ 15    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Whatever fraud there is in Medicaid is largely on the provider side, not beneficiaries. It's health insurance, its not cash.

"Fraud" here means going to a doctor if you are unemployed.

10.04.2025 17:04 β€” πŸ‘ 3364    πŸ” 834    πŸ’¬ 190    πŸ“Œ 37
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🚨 Hot off the press! 🚨 The @myesmo.bsky.social ESMO Precision Oncology Working Group, has unveiled key "Recommendations for structuring Molecular Tumour Boards (MTBs) in clinical practice", now published in ESMO's flagship journal Annals of Oncology 🧬πŸ₯
www.annalsofoncology.org/article/S092...

08.04.2025 02:16 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Low-dose CT for lung cancer screening in a high-risk population (SUMMIT): a prospective, longitudinal cohort study out on LANCET Oncology

www.thelancet.com/journals/lan...

These findings support the feasibility and effectiveness of large-scale lung cancer screening in a diverse population.

02.04.2025 16:18 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

I understand this concern, but the anti-vaxx arguments are already everywhere on social media. We have to have people refuting this stuff. Can’t let it go completely unchecked.

31.03.2025 16:51 β€” πŸ‘ 307    πŸ” 17    πŸ’¬ 7    πŸ“Œ 0
SCiMaP

Just in NIH grants, It looks like beautiful Iowa City, home of the U of Iowa, will lose $71m in funding. That's almost $1k per resident. And that's before all the other cuts to SSA, FDA, etc.

Anyone in Iowa City that can offer more insight?
scienceimpacts.org
H/T to Prathima !

29.03.2025 18:29 β€” πŸ‘ 19129    πŸ” 5694    πŸ’¬ 906    πŸ“Œ 257
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The Trump administration restructures federal health agencies, cuts 20,000 jobs The reduction in force comes along with a reorganization of the Department of Health and Human Services, consolidating 28 divisions to 15.

This is not efficiency, this is abandonment.

Americans deserve health care that works for them β€” and instead, the Trump administration is wreaking havoc on seniors, people with disabilities, and our most vulnerable.

In Illinois, we will stand up against these attacks.

27.03.2025 18:31 β€” πŸ‘ 1640    πŸ” 349    πŸ’¬ 59    πŸ“Œ 23
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US Department of Health and Human Services to lay off 10,000 employees Cuts will affect the Food and Drug Administration, Centers for Disease Control and Prevention, and the National Institutes of Health

The NIH is set to lose ~1,200 ppl as part of the HHS restructuring.

An NIH researcher had not yet received news internally about plans to restructure the agency as of Thursday morning, less than an hour after Kennedy's statement published. cen.acs.org/policy/US-De... @cenmag.bsky.social #chemsky

27.03.2025 17:37 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 1    πŸ“Œ 0
Small-molecule RNA therapeutics to target prostate cancer Kuzuoglu-Ozturk etΒ al. showcase a therapeutic approach, β€œtranslatome therapy,” to combat lethal prostate cancer. Zotatifin, a clinical molecule, targets the RNA-helicase eIF4A. Zotatifin decreases the select translation of key oncogenes, androgen receptor (AR), and HIF1Ξ± through remodeling their 5β€² UTR RNA structure. Zotatifin enhances anti-androgen and radiotherapy sensitivity, highlighting a promising anti-cancer treatment.

Happy to share our new work with @haognguyen on targeting mRNA translation of oncogenes by RNA structure remodeling with a small molecule zotatifin. Congrats to ⁦@DuyguKuzuoglu⁩ an amazing postdoc and all the authors and collaborators!

cell.com/cancer-cell/fu…

20.03.2025 15:59 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

A friend drove two hours today for her breast cancer chemotherapy only to learn it was canceled due to NIH cuts. Clinical trial ended midstream. No treatment, no restart, no plan, no information. Her bro-in-law's chemo was also canceled.

20.03.2025 20:24 β€” πŸ‘ 23285    πŸ” 9868    πŸ’¬ 1644    πŸ“Œ 1261

"more transparency throughout [the #priorAuth] process is great, I remain concerned that relying on patients & physicians to recognize & initiate appeals places disproportionate burden on our patients who can least afford it."

@michaelannica.bsky.social
@ascocancer.bsky.social

20.03.2025 15:41 β€” πŸ‘ 10    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0
Oreo CEO:  Stop Making New Oreos
YouTube video by Dropout Oreo CEO: Stop Making New Oreos

So many Oreo options!
www.youtube.com/watch?v=CMkY...

19.03.2025 21:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Do these clinical trial failures demonstrate a failure of traditional pre-clinical models to reflect the human disease?

In addition to the complete avoidance of biomarker-driven clinical trials to find the subset of patients that would benefit.? @asharpmedonc.bsky.social @pcf-science.bsky.social

17.03.2025 13:48 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
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Immune Checkpoint Combos in Metastatic Castration-Resistant Prostate Cancer: Where Are We Going, What Are We Doing, and Why?

Dr. Susan Slovin from MSK asks some key questions regarding #ProstateCancer #Immunotherapy

@ascocancer.bsky.social

ascopubs.org/doi/10.1200/...

17.03.2025 13:21 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
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Vaccines work.
Measles, polio, smallpoxβ€”once devastating, now nearly gone. This is what science achieves when we trust it. Let’s not turn back.
#VaccinesSaveLives #PublicHealth #ScienceMatters
@statista.bsky.social

09.03.2025 15:00 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

@joshlangmd is following 19 prominent accounts