Takashi Nakamura

Highly polar stacking interactions wrap inorganics in organics: lone-pair–π-hole interactions between the PdO4 core and electron-deficient arenes Cocrystallization of the palladium acetate cluster Pd3(OAc)6 (abbreviated as [Pd3]) with electron-deficient iodine(i)-based perfluoroarenes (ArFI: iodopentafluorobenzene, 4-iodoheptafluorotoluene, 1,4...

Today's daily morning seminar
doi.org/10.1039/d1qi...

A Robust Heterometallic Pt2Pd2L8 Double Cage Catenane The first heterometallic Pt(II)–Pd(II) quadruply interlocked cage catenane (Pt2Pd2L8) has been assembled via a combination of metal-mediated self-assembly and dynamic covalent chemistry. The integrat....

Today's daily morning seminar
doi.org/10.1002/anie...

Asymmetric Cobalt Single-Atom Catalysts with Engineered Hydrophobic Microenvironment: A Reaction-Transport Coupled Strategy for Efficient Methyl Oleate Epoxidation The depletion of fossil resources and the urgent demand for biodegradable alternatives drive innovations in transforming renewable vegetable oils into high-value chemicals. Despite substantial progres...

Today's daily morning seminar
doi.org/10.1021/jacs...

Synthesis of triple stranded porphyrin nanobelts Molecular nanobelts are fascinating analogs of carbon nanotubes. Their rigid geometries and strongly coupled π-electrons have the potential to generate a wave function resembling that of a quantum rin...

Today's daily morning seminar
doi.org/10.1126/scie...

Facile Access to Quaternary Carbon Centers via Ni-Catalyzed Arylation of Alkenes with Organoborons Quaternary carbon centers are widespread structural motifs, thus representing extensive interest in organic synthesis. We describe here an efficient nickel-catalyzed intermolecular, Markovnikov-select...

This week's journal club
doi.org/10.1021/jacs...

Synthesis of Degradable Polyimines Through Deborylative Polycondensation Here we demonstrate the general, room-temperature, and scalable synthesis of degradable polyimines by deborylative polycondensation under anhydrous and neutral conditions, which can improve the degre....

This week's journal club
doi.org/10.1002/anie...

Template Assisted One‐Pot Synthesis of [2], Linear [3], and Radial [4]Catenane via Click Reaction Using a non-labile Co (III) metal template and click reaction followed by de-metalation, synthesis of [2], linear [3], and radial [4] catenane has been achieved. Synthesized templated linear [2] cate...

Today's daily morning seminar
doi.org/10.1002/asia...

Ligand Architecture Control Geometry, Self-Sorting, and Postsynthetic Modification in Anthracene-Based Organometallic Assemblies Although various skeletons of organic ligands have been applied to achieve the structural diversity of metallasupramolecular assemblies, limited approaches are available for organometallic cluster-bas...

Today's daily morning seminar
doi.org/10.1021/jacs...

Cationic Hosts with Preorganized Conformation for Anion Recognition A tetracationic macrocycle and a hexacationic cage bearing four and six pyridinium units, respectively, were synthesized via an SN2 reaction in a one-pot manner. Both of these hosts have relatively ri...

Today's daily morning seminar
doi.org/10.1021/acs....

Today's daily morning seminar
doi.org/10.1038/s415...

Single-Crystal X-ray Structures of Homochiral Brønsted Acidic Covalent Organic Frameworks Determining the crystal structures of covalent organic frameworks (COFs) with atomic precision is pivotal for uncovering their properties and optimizing functionalities. However, the synthesis of high...

Today's daily morning seminar
doi.org/10.1021/jacs...

Inverted azolophanes: alternant o-heteroarene/p-arene macrocycles Using the Debus–Radziszewski reaction, eight imidazole-based macrocycles were synthesized from cyclotetrabenzil, while three oxazole analogs were prepared by the Davidson oxazole synthesis starting wi...

Today's daily morning seminar
doi.org/10.1039/d5sc...

Unraveling the Molecular Pathways for Structure “Making” and “Breaking” by Ions in Water Aqueous anions play a crucial role in chemical and biological processes. They are traditionally classified as “structure makers” or “structure breakers” based on their impact on the viscosity of elect...

Today's daily morning seminar
doi.org/10.1021/jacs...

An Isolated Lithium ortho-Carboranyl Cuprate Complex for the Synthesis of Multiple-Carborane-Substituted Arenes from (Hetero)Aryl Bromides and Chlorides Carborane-substituted arenes have emerged as versatile building blocks in medicinal chemistry, materials science, and coordination chemistry owing to the unique three-dimensional aromaticity, exceptio...

Today's daily morning seminar
doi.org/10.1021/jacs...

Chiral Self‐Sorting of Flexible Covalent Organic Pillars for Adaptive Molecular Recognition Flexible covalent organic pillars (flex-COP-n) are adaptive nanotubular hosts formed via dynamic imine condensation. Their self-assembly displays an odd–even effect, yielding enantiomeric or meso dup...

This week's journal club
doi.org/10.1002/anie...

Metal‐Free Active Template Synthesis of Catenanes A new strategy for catenane synthesis is reported that does not require persistent strong binding interactions on the components nor the addition of templates. Metal-free active template synthesis sp...

This week's journal club
doi.org/10.1002/anov...

In Search of Wasserman’s Catenane We repeat the earliest claimed [2]catenane synthesis, reported by Wasserman over 60 years ago, in order to ascertain whether or not a nontemplate, statistical synthesis by acyloin macrocyclization doe...

Today's daily morning seminar
doi.org/10.1021/jacs...

Odorless and Air-Stable Thionating Reagent for Broad Scope Thioamide Synthesis without H2S Emission A novel thionating reagent, 7-phenyl-2,4,6,8,9-pentathia-1,3,5-triphosphaadamantane 1,3,5-trisulfide (1), bearing an S–P adamantane framework, has been developed as a practical and environmentally ben...

A collaboration with Prof. Kutsumura in the department and co-workers is now published.
Congratulations!!
doi.org/10.1021/acs....

Reversible Mechanical Interlocking via Stimuli‐Triggered Nonhomeomorphic Topology Transformation Enables Highly Efficient Rotaxane Synthesis We design the macrocycles capable of stimuli-triggered, reversible transformation between nonhomeomorphic topologies (one-hole ring versus two-hole figure-eight ring). By leveraging the ring size cha....

Today's daily morning seminar
www.doi.org/10.1002/anie...

Synthesis of Imine-Phenoxy Ligated Palladium Complexes for Norbornene Homopolymerization Metal complexes with tunable ligands play a crucial role in olefin polymerization and impart control over molecular weight, crystallinity, and stereoregularity. We report the single-step synthesis of imine-phenoxy ligands in excellent yields (81–93%). The identity of electronically tuned imine-phenoxy ligands was unambiguously ascertained by using a combination of spectroscopic and analytical methods. These ligands were treated with [Pd(COD)MeCl] in the presence of 2,6-lutidine, resulting in the formation of discrete mononuclear palladium complexes Pd1–Pd4 in excellent yields. 1–2D NMR spectroscopy, mass spectrometry analysis, and single-crystal X-ray diffraction confirmed the identity of the palladium complexes. X-ray analysis revealed a distorted square planar geometry around the palladium center. Proton NMR analysis suggested that the Pd1 catalyst was deshielded, indicating electronically deficient palladium metal compared to the other complexes. Moreover, the Pd1 catalyst showed the highest buried volume percentage (%Vbur = 44.9). When exposed to norbornene, Pd1–Pd4 were found to be active and produced poly(norbornene) (PNB). High-temperature SEC analysis revealed that the electronically deficient and sterically hindered Pd1 catalyst produced the highest molecular weight polymer (PNB 37.4 kDa). Boron and aluminum-based cocatalysts were screened, and MMAO was found to outperform others with high catalytic activity (up to 63.2 × 105 g of PNB (mol Pd)−1 h–1).

Today's daily morning seminar
doi.org/10.1021/acs....

Structural Control of Band Gap and Polaron Delocalization in 2D Azatriangulene Covalent Organic Frameworks New two-dimensional (2D) covalent organic frameworks (COFs) with a tri(oxa)azatriangulene (TANG) node and different polarity of the imine linkers (C═N vs N═C) and internode distance have been synthesi...

Today's daily morning seminar
doi.org/10.1021/jacs...

Engineering Cavity and Aperture Binding Sites Within a Metal–Organic Cage for Up‐ and Down‐Regulation of Catalysis Precisely controlling the up- or down-regulation of catalysis in a biomimetic fashion is a challenging goal in supramolecular chemistry. Here, the inclusion complex of Mo8O264− within a metal–organic....

Today's daily morning seminar
doi.org/10.1002/anie...

Cyclic BODIPY Arrays: A Class of Macrocycle-Based Molecular Solids for Hydrogen Isotope Separation and Iodine Capture Macrocyclic hosts are pivotal in supramolecular chemistry, yet the discovery of synthetically scalable platforms that combine rich host–guest behavior, facile crystallizability, and solid-state functi...

Today's daily morning seminar
doi.org/10.1021/jacs...

A Fluorescent and Switchable Rotaxane Dual Organocatalyst Rotaxane organocatalysis presents a new direction toward controlled one-pot catalytic reactions. By combining molecular switches and catalysts, fluorescence and pH-responsive switching along with the ...

Today's daily morning seminar
doi.org/10.1021/acs....

Photoresponsive macrocycles for selective binding and release of sulfate A series of new photoresponsive macrocyclic anion receptors were synthesized via integration of an azobenzene unit and multiple anion binding sites. They exhibited highly selective binding to dianioni...

Today's daily morning seminar
doi.org/10.1039/d1cc...

Remote Hydrogen Bonding between Ligand and Substrate Accelerates C–H Bond Activation and Enables Switchable Site Selectivity A spirobipyridine ligand bearing a hydroxy group recognizes pyridine and quinoline substrates through hydrogen bonding, and in combination with an iridium catalyst enables C−H borylation with site se....

Today's daily morning seminar
doi.org/10.1002/anie...

Today's daily morning seminar
doi.org/10.1021/jacs...

Diastereoselective Synthesis of N-Glycosides via Buchwald–Hartwig Coupling Herein we report a practical and highly efficient methodology for the β-selective synthesis of N-glycosides via Buchwald–Hartwig coupling. This glycosylation strategy employs glycosyl chloride with di...

Today's daily morning seminar
doi.org/10.1021/acs....

An 18-Porphyrin Nanoring at the Size Limit for Global Aromaticity What is the size limit for global aromaticity? How large can a macrocyclic π-system be and still exhibit an aromatic ring current around its circumference? We address this question by investigating a ...

Today's daily morning seminar
doi.org/10.1021/jacs...

Today's daily morning seminar
doi.org/10.1021/acs....