Wai-Hong Tham

Last week we had the CCeMMP Symposium 2025. Fantastic event with an outstanding line-up of speakers. There were 2 poster prizes and 1 oral presentation prize; thrilled that we did a clean sweep! Huge congratulations @tiltedscientist.bsky.social @somavallyd.bsky.social and @lucatroman.bsky.social

Excited to share matchbox. It’s super fast and versatile to search for patterns in reads, I’m curious to see all the uses it will find!
Congrats to @jakobschuster.bsky.social , co-supervisors @michaelbclark.bsky.social @mritchieau.bsky.social and team!
www.biorxiv.org/content/10.1...

Slide showing which countries have national research integrity offices

Speaker at the lectern

Next up: David Vaux with "An Office for Research Integrity in Australia – What are the barriers?"
* 23 European countries and 6 others have offices for research integrity.
* Australia has a guide with principles and responsibilities but institutions essentially investigate themselves.

#IRICSydney

Me too!

Introducing Dr Jaison D Sa @jaisondsa.bsky.social who was awarded his PhD from University of Melbourne 🎉🎉

Co-supervised by Phillip Pymm and me

🩸Stabilized vivax antigen for serodiagnostics
🧬 Alpseq open source nanobody discovery workflow
🦙Nanobodies to Plasmodium adhesins – watch this space!

Why the conspiratorial right rallied around a flock of ostriches The anti-vaccine, anti-government crusade to save "the miracle cure birds" is over — and the fringe activists lost.

The ostriches have been culled and that particular H5N1 outbreak has finally been contained.

Here is @brandyzadrozny.bsky.social's reliably excellent account of the entire ordeal.

www.msnbc.com/news/news-an...

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine salvage. Purine salvage represses DNPB to prevent excessive purine nucleotide synthesis through mechanisms that ...

1/New paper from Zheng Wu, Phong Nguyen et al. @cri-utsw.bsky.social shows how cells balance the two pathways that produce purine nucleotides: de novo purine biosynthesis (DNPB) and purine salvage. The surprising mechanism involves NUDT5, a Nudix hydrolase

www.science.org/doi/10.1126/...

We’re delighted to share our most recent quarterly report from Altmetric Explorer to showcase the top 5 trending articles from across our publications, ranked by Altmetric score. See the thread below for trending articles and find out more here: buff.ly/rcMJA2N

ARC grant scheme timetable, including open, close and anticipated outcome announcement dates for Expressions Of Interest and full applications, plus rejoinder periods and selection meeting dates.

#ARCschedule Nov25

Outcomes expected for DECRA, LIEF & presumably(?) Centres of Excellence ("postponed" on 3 Nov).

Other events:
🔹Open: Discovery Projects EOI
🔹Close: ITRP & Future Fellowships
🔹Selection meeting: Linkage Projects (2025 round 2)

Data ▶️ docs.google.com/spreadsheets...

Close up picture of a triggerplant flower in pink and white. The top two petals are smaller than the two bottom petals which are broadly rounded at their tips

Picture of a triggerplant with numerous flowers in pink and white. The top two petals of each flower are smaller than the two bottom petals, which are broadly rounded at their tips

Stylidium utricularioides - the Pink Fan Triggerplant

One of the triggerplants endemic to Western Australia, this distinctive species grows in winter wet areas and flowers in late spring through to early summer

#ozflora #wildoz #nativeplants #inaturalist #nature

Screenshot of ARC "network messages" webpage stating that Centres of Excellence outcomes are "postponed". Blue text on white background as a heading, above an image of concentric part circles, to make a sort-of whirlpool pattern, above black text on white background.

#CentresOfExcellence #CE26

ARC has "postponed" announcement of Centres of Excellence outcomes!

It says "due diligence checks" are still being carried out on some applications.

www.arc.gov.au/news-publica...

The common cuckoo (Cuculus canorus) has evolved egg features (top row) to mimic eggs of different host species (bottom row). PHOTO: SWETLANA MESHCHERYAGINA0

Stunning illustration of mimicry! Common cuckoo eggs (top row) imitate the eggs of their host species (bottom row). The 30 October issue of Science explains this dazzling coevolution with genomic data — though I admit, it’s complex enough that I’d struggle to teach it! 🧪🌿🌎🦉

Really interesting interview. @timcoulson.bsky.social and I were also fortunate to chat with David Baker on our podcast which you can catch here: Science Of The Times EP7 Pt2 - Interview with 2024 Nobel Prize winner for Chemistry David Baker
youtu.be/jShxgJ3XrWA

I promised myself that when I next had a successful grant, I'd share a snapshot of my trail of unfunded submissions.

With gratitude to the ARC, looking forward to next several years of collaboration on effort motivation with @minzlicht.bsky.social, Deena Skolnick Weisberg, and Frederik Anseel!

Registrations for the Stromlo Plant Pathogen Conference #StromPath25 are rolling in fast and the program is now full!
Exciting lineup from Japan, Korea, USA, UK, NZ + strong local crew. Join us in Canberra — rego open until Nov 13.
Program available here tinyurl.com/3e3tx9j2

We are looking for a computational postdoc to work with us on new optimisation algorithms to make #RELION even better. Join our bubbly team at the @mrclmb.bsky.social in Cambridge, UK. 🤗 RTs appreciated.

mrc.tal.net/vx/appcentre...

Professor Susanne von Caemmerer and Professor Graham Farquhar are receiving an award.

Plant scientists Professor Graham Farquhar and Professor Susanne von Caemmerer transformed the world's understanding of photosynthesis, and now they have been jointly awarded the Royal Medal (Biological) from The Royal Society, at a ceremony in London.

science.anu.edu.au/news-events/...

alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...

Keen to use an open source workflow for nanobody discovery? Check out Alpseq 🦙

Alpseq’s diversity analysis, enrichment counts & clustering allow different approaches for nanobody selection

Great collab with bioinformaticians @qgouil.bsky.social Kathleen Zeglinski

www.biorxiv.org/content/10.1...

Banner for a job ad for an Engagement Officer. 'Now hiring' is shown above a group of people standing in front of a domed building.

We’re hiring an Engagement Officer for the ISC Asia–Pacific Regional Focal Point. Based in Canberra (or remote for the right candidate). Closes 4 November.
Apply now: www.science.org.au/about-us/car... @iscasiapacific.bsky.social

Screenshot of tweet from the ARC saying they will announce DP26 outcomes on Tuesday 28th Oct, and LP25r1 outcomes on Wednesday 29th.

ARC says Discovery Projects outcomes will be tomorrow (Tuesday). Linkage Projects (2025, round 1) on Wed. Over past ~year, it's often been at about 11am (Canberra).

My bot will pick up the change to RMS & post immediately.

ARC should email outcomes to lead CIs, but might take an 1hr or so for DPs

alpseq: an open-source workflow to turbocharge nanobody discovery with high-throughput sequencing Nanobodies have emerged as promising tools for many biotechnological applications due to their small size, high stability, and remarkable binding specificity. Next-Generation Sequencing (NGS) enables ...

Excited to share our new preprint: alpseq - an open-source workflow to turbocharge nanobody discovery! 🦙
doi.org/10.1101/2025...
This work is the result of Kathleen Zeglinski’s brilliant PhD work and an outstanding collaboration with Wai-Hong Tham's group!
Find alpseq at github.com/kzeglinski/a...

On an Arctic archipelago, frozen soil may preserve a hidden history of viruses Scientists are hunting for ancient RNA in Svalbard’s permafrost, hoping to shed light on the evolution of viral diseases

I am fascinated by how viruses evolve - and not just since #SARSCoV2 has shown us at the global stage how consequential virus evolution can be for us.
In my new story in @science.org I got to explore how researchers are probing deeper into the past with old RNA virus genome.
So a 🧪 thread…

Postdoctoral Research Assistant - MCDB - UOD2016 Closing date: Thursday 6 November 2025, 23:59

Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.

www.dundee.ac.uk/work-for-us/...

Congratulations 👏We have a winner for the 2nd ARC CCeMMP Bench to Art Exhibition🥇Our judges awarded the first prize to Laura Humphrys - 'Too Hot To Chandle'! 👏More info on our website: ccemmp.org/events/arc-c...

And congratulations to Muyuan Chen - "Cat jumping from respiratory complex", awarded the third prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...

Congratulations also to Kenta Ishii and the entry 'One and four GLP-1Rs', which was awarded the second prize at the 2nd ARC CCeMMP Bench to Art Exhibition👏More info on our website: ccemmp.org/events/arc-c...

Firing measles experts in the midst of a measles outbreak seems highly logical and smart

🤦🏽‍♂️

Open Group Leader Positions at the IMB, UQ. Interested in joining us in sunny Queensland?

Incredible two days @cssbhamburg.bsky.social as Scientific Advisory Board and to hear about integrative structural biology for infectious diseases 🦠🧫🔬

🙏Hans-Georg Kräusslich, @oneyrolles.bsky.social , @sykhalid.bsky.social Joost Enninga, Friedrich Förster, Ilaria Ferlenghi for open discussions

Poster Session during our SAB Meeting!

Thanks to everyone who shared their research with our SAB members.

@landaulabcssb.bsky.social @topf-lab.bsky.social @bosse-lab.bsky.social @jankosinski.bsky.social @thamlab.bsky.social @oneyrolles.bsky.social @sykhalid.bsky.social