Joel Selkrig's Avatar

Joel Selkrig

@jselkrig.bsky.social

Updates from the Selkrig Lab. Exploring the function of secreted bacterial proteins in the context of infection and the gut microbiome. www.ukaachen.de/kliniken-institute/institut-fuer-medizinische-mikrobiologie/forschung/ag-selkrig/

450 Followers  |  331 Following  |  9 Posts  |  Joined: 06.12.2023  |  1.8711

Latest posts by jselkrig.bsky.social on Bluesky

Weโ€™re hiring! A PhD position (E13 TV-L, 65%) is available at @cmfi.bsky.social @unituebingen.bsky.social. The DFG-funded project explores how mechanical forces shape intracellular bacterial infections, focusing on Listeria. Details & application: www.euraxess.de/jobs/366585. Start: ASAP!

06.08.2025 09:20 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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๐ŸŒŸVAAM Early Career Network Event๐ŸŒŸ
๐Ÿ“… Sep 16, 2:30 PM, Zoom โœ๏ธhttps://t1p.de/jx2sz
๐ŸŽฏ"From late Postdoc to early PI: Applications, Funding, Appeals & Alternative Paths"
๐Ÿ’กReady to take the next step? Get practical advice on funding applications, handling setbacks & discovering alternative career paths

05.08.2025 12:11 โ€” ๐Ÿ‘ 4    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Open Call for Expressions of Interest in Max Planck Directorships:
Expressions of interest can be submitted until 31 October 2025.

Open Call for Expressions of Interest in Max Planck Directorships: Expressions of interest can be submitted until 31 October 2025.

Director at Max Planck - a unique position! The Open Call for Expressions of Interest in Max Planck Directorships is open now and can be submitted by the 31st of October 2025. โžก๏ธ mpg.de/directors - Please share the Open Call among potential candidates.

01.08.2025 09:06 โ€” ๐Ÿ‘ 157    ๐Ÿ” 184    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 13
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Group leader positions in @sangerinstitute.bsky.social Cellular Genomics, led by @mhaniffa.bsky.social, to decode and recode human tissues. Broad net - clinical research, in vitro models, single cell, AI. Vibrant, supportive community. Please share!

sanger.wd103.myworkdayjobs.com/en-GB/Wellco...

31.07.2025 07:55 โ€” ๐Ÿ‘ 10    ๐Ÿ” 16    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Group Leader โ€“ Molecular Systems Biology Unit Are you ready to lead groundbreaking research in Molecular Systems Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group, addressing original biological ...

Ready to lead pioneering research that bridges systems-level investigations of biological systems to molecular mechanism? The EMBL Molecular Systems Biology Unit in Heidelberg is hiring a Group Leader!

30.07.2025 15:14 โ€” ๐Ÿ‘ 71    ๐Ÿ” 78    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1

Congratulations Michael and Co!

30.07.2025 20:35 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Peptidoglycanโ€“outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria - Nature Microbiology Outer membrane attachment to peptidoglycan enables periplasmic pressure to build up and counter cytoplasmic turgor pressure, preventing lysis during osmotic challenges in Escherichia coli.

#microsky
We challenge the long-standing view that peptidoglycan alone protects cells from bursting.

Our study shows that the periplasm โ€” enclosed by OMโ€“PG connections โ€” acts as a pressure buffer essential for osmoprotection in Gram-negative bacteria.

๐Ÿ“„ www.nature.com/articles/s41...

29.07.2025 13:23 โ€” ๐Ÿ‘ 44    ๐Ÿ” 28    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
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Group Leader - Genome Biology Unit Are you ready to lead groundbreaking research in Genome Biology? Join us at EMBL! We are seeking a motivated scientist to lead an independent research group addressing exciting and original biological...

To all post-docs: The Genome Biology dept โ€ช@embl.org
has an Independent faculty position. Fantastic place to set up your lab โ€“great package: core funding, fantastic Ph.D. students, cutting edge core facilities & great colleagues. Closing date Sept 19th
embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

30.07.2025 13:41 โ€” ๐Ÿ‘ 170    ๐Ÿ” 201    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 7
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PhD student in Biochemistry - Uppsala University PhD student in Biochemistry, Disciplinary Domain of Science and Technology, Faculty of Chemistry, Department of Chemistry - BMC, Uppsala University

We are looking for a PhD student in (mostly )wet-lab biochemistry to work on short linear motifs, intrinsically disordered regions, in the context of the Marie Curie network "IDPro". More info an apply here: www.uu.se/en/about-uu/...

30.06.2025 08:39 โ€” ๐Ÿ‘ 10    ๐Ÿ” 21    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1

Our review on contact-dependent #predation is now out ! We define predation processes and describe how predators kill and eat their prey ๐Ÿ˜ˆ Repost appreciated โค๏ธ

25.07.2025 20:51 โ€” ๐Ÿ‘ 15    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Non-antibiotics disrupt colonization resistance against enteropathogens Nature - Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of...

Finally online!
Our latest research is out @nature.com: We show that non-antibiotic drugs can disrupt colonization resistance, raising the risk of enteric infections.
rdcu.be/ewwrG

16.07.2025 21:20 โ€” ๐Ÿ‘ 88    ๐Ÿ” 42    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
Emmy Noether Programme:
in English
Friday, 18. July 2025, 10-11:30 a.m. CET

Emmy Noether Programme: in English Friday, 18. July 2025, 10-11:30 a.m. CET

#Prospects PhDs & postdocs of all disciplines note: Would you like to lead an independent junior research group? In our online talk you will get first-hand information about the aims and requirements of the DFG Emmy Noether Programme and more. Link to the meeting will be published here: fcld.ly/enp

09.07.2025 13:29 โ€” ๐Ÿ‘ 37    ๐Ÿ” 21    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3
Portail Emploi CNRS - Offre d'emploi - Ingรฉnieur d'Etude en Microbiologie (H/F)

We have an open engineer position to work on type IX secretion (T9SS), under the supervision of @doan_thierry (collab with HP Fierobe & A. Tolonen). 1-year contract, renewable up to 3.5 years. Please apply here or forward to anyone potentially interested:

emploi.cnrs.fr/Offres/CDD/U...

08.07.2025 14:54 โ€” ๐Ÿ‘ 23    ๐Ÿ” 32    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A porin-like protein used by bacterial predators defines a wider lipid-trapping superfamily - Nature Communications This study reveals that an outer membrane protein from the predator Bdellovibrio bacteriovorus forms a pentameric assembly that traps a lipid monolayer within. This allows the discovery of two superfa...

Check out these amazing lipid-monolayer-trapping oligomeric OMPs published by @lalouxlab.bsky.social and Lovering Labs. The BAM complex in these bugs must be wild!

www.nature.com/articles/s41...

06.07.2025 06:54 โ€” ๐Ÿ‘ 43    ๐Ÿ” 15    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2
Human gut bacteria bioaccumulate PFAS

Human gut bacteria bioaccumulate PFAS

Excited to share some key details on our latest research in @natmicrobiol.nature.com reporting intra-cellular accumulation of #PFAS (aka forever chemicals) by certain human gut bacteria. #microsky #mevosky #microbiomesky
www.nature.com/articles/s41...

02.07.2025 14:56 โ€” ๐Ÿ‘ 57    ๐Ÿ” 32    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 1
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Also had the honor of meeting @jeremyjbarr.bsky.social and hearing about his exciting data on gut prophages

01.07.2025 20:03 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Last week I had a blast co-hosting the 17th Annual SeeOn conference www.dghm.org/seeon/ for โ€œMicrobiota, Probiotics and Hostโ€, together with Till Strowig and @lisamaierlab.bsky.social . Excellent location, top quality science and a fun atmosphere!

01.07.2025 19:54 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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The pill that might be relieving your heartburn but killing your gut microbes Why drugs commonly used against heartburn harm your gut microbiome

Big thanks to scientific writer Libera Lo Presti for this great little piece on our recent work exploring how proton pump inhibitors (PPIs) and pH affect human gut microbes.
Check it out here: go.nature.com/4lf6jNk

19.06.2025 21:10 โ€” ๐Ÿ‘ 23    ๐Ÿ” 15    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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A scalable gut epithelial organoid model reveals the genome-wide colonization landscape of a human-adapted pathogen - Nature Genetics A genome-wide screen using human gut epithelial organoids combined with transposon-directed insertion sequencing identifies over 100 Shigella flexneri genes required for epithelial colonization.

New study with an organoid model uncovering the role of tRNA modifications and codon usage in Shigella infection ๐Ÿฆ  #rnasky #microsky ๐Ÿ’ซ๐Ÿ’ซ www.nature.com/articles/s41... Congrats @mldm.bsky.social

12.06.2025 17:45 โ€” ๐Ÿ‘ 13    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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UZH: Postdoctoral researcher in microbiology The Department of Quantitative Biomedicine is an interdisciplinary biomedical research unit that combines basic science with biotechnological and medical research, using both experimental and computat...

We are looking for a highly motivated postdoc to work on pathogen interactions. Please send in your application via

jobs.uzh.ch/job-vacancie...

10.06.2025 14:14 โ€” ๐Ÿ‘ 25    ๐Ÿ” 34    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 5
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Associate or Senior Editor (Nature Structural & Molecular Biology and Nature Communications) Job Title: Associate or Senior Editor (Nature Structural & Molecular Biology and Nature Communications) Location: New York, Shanghai, Beijing, Madrid or Milan Closing date: June 20th About Springe...

So excited to share that we @natsmb.nature.com are hiring a new editor! If you are interested about working with an intelligent, compassionate and funny team helping scientists publish great research, please consider applying. Deadline June 20th. springernature.wd3.myworkdayjobs.com/SpringerNatu...

10.06.2025 18:44 โ€” ๐Ÿ‘ 5    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
DMF: Tenure Track Assistant Professor towards Associate Professor in Molecular Microbiology - Site des postulations FBM

New tenure track assistant professor position in molecular microbiology in our department @dmf-unil.bsky.social @unil.bsky.social! We are casting a wide net for an experimental molecular microbiologist. Apply here: wwwfbm.unil.ch/releve/appli...

10.06.2025 13:53 โ€” ๐Ÿ‘ 112    ๐Ÿ” 162    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 8
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Together with @gtavosanis.bsky.social we secured an ERS (Exploratory Research Space) Seed Fund grant from RWTH Aachen University for our collaborative project, โ€œMicro-Pain: Mechanisms of Microbe-Dependent Pain Perception.โ€!!!

09.06.2025 20:44 โ€” ๐Ÿ‘ 13    ๐Ÿ” 2    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 0
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Elucidating the mechanisms of action and evolutionary history of phage anti-defence proteins Phages and bacteria are locked in a molecular arms race, with phage anti-defence proteins (ADPs) enabling them to evade bacterial immune systems. To streamline access to information on ADPs, we develo...

Very excited to share our preprint on a new resource: the Encyclopaedia of Viral Anti-Defence Systems (EVADES)! This is the main result of my PhD at โ€ชEMBL-EBI (@ebi.embl.org)โ€ฌ
and the University of Cambridge (@cam.ac.ukโ€ฌ)! ๐Ÿ”— www.biorxiv.org/content/10.1... ๐Ÿงต1/n"

08.06.2025 11:08 โ€” ๐Ÿ‘ 56    ๐Ÿ” 26    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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PhD Scholarships at Monash University - MACSYS Do cutting-edge research at the frontiers of Whole Cell Modelling! The MACSYS Node at Monash University has multiple PhD Scholarships available to work on some exciting projects! $41,753 p.a. stipend ...

Great science looks at big unknowns.

In bacteria, sRNAs control gene expression but โ€˜howโ€™ they do this at systems level is far from known. @MACSYS is recruiting for courageous PhD students who would learn, know and report how sRNAs deliver systems level phenotypes

macsys.org/monash-phd-s... for

25.05.2025 06:29 โ€” ๐Ÿ‘ 6    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Had a LOT of fun opening the 3-day 'Pint of Science' Festival here in Aachen and sharing our enthusiasm for gut microbes! Already looking forward to next year #Pint25 #Pint25de

20.05.2025 18:17 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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๐Ÿ”ฅ The "Postdoc Night Science Germany" club will have its first meeting this Friday, May 16 at HHU Dรผsseldorf. Join us postdocs for a session on how to find the gorilla hiding in your data! I'll lead this together with Martin Lercher. Register here: docs.google.com/forms/d/1zgb...

10.05.2025 21:01 โ€” ๐Ÿ‘ 25    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Enabling next-generation anaerobic cultivation through biotechnology to advance functional microbiome research Nature Biotechnology - Overcoming key hurdles for the development of next-generation anaerobic cultivation methods could have major impacts on microbial community research and applications.

Here we share thoughts on next-gen cultivation: rdcu.be/ejPSb. Hope it helps ๐Ÿ˜„ Was fun to write with great colleagues @lisamaierlab.bsky.social @jselkrig.bsky.social @baerboletta.bsky.social @typaslab.bsky.social @mmmicrobiomelab.bsky.social @leibniz-dsmz.bsky.social @westermannlab.bsky.social

29.04.2025 11:58 โ€” ๐Ÿ‘ 27    ๐Ÿ” 19    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

... and don't miss the opportunity to meet @jeremyjbarr.bsky.social and other great speakers at the upcoming Seeon Conference in June โญโญโญโญโญ www.dghm.org/seeon/

16.04.2025 06:54 โ€” ๐Ÿ‘ 2    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Structure and infection dynamics of mycobacteriophage Bxb1 Mycobacteriophage Bxb1 is a well-characterized virus of Mycobacterium smegmatis with double-stranded DNA and a long, flexible tail. Mycobacteriophagesโ€ฆ

Hurray, it is finally out! Meet bacteriophage Bxb1 - the subject of my first full-phage cryo-EM study. My structures are beautifully complemented by the Park Labโ€™s cryo-ET analysis, shedding light on mycobacteriophage structural changes during infection.

www.sciencedirect.com/science/arti...

16.04.2025 12:50 โ€” ๐Ÿ‘ 69    ๐Ÿ” 28    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 4

@jselkrig is following 20 prominent accounts