Vallier Lab

Many exciting opportunities for a PhD in Life Sciences in CRG, Barcelona. If you are interested in Genomics of Diabetes check out the offer for a fully funded fellowship in our lab - we will consider candidates with experimental or computational backgrounds.

Please spread the word!

Towards a reference cell atlas of liver diversity over the human lifespan Nature Reviews Gastroenterology & Hepatology, Published online: 13 October 2025; doi:10.1038/s41575-025-01114-3This Roadmap presents and outlines the creation of the Human Liver Cell Atlas as a reference map and resource for the liver community, providing an overview of the steps needed to build the atlas, as well as outlining the major challenges and potential of this venture.

ICYMI: New online! Towards a reference cell atlas of liver diversity over the human lifespan

Early bird today, I am on my way to the @gscnoffice.bsky.social conference, representing the @vallierlab.bsky.social together with Ferhat Ali Yaman. Looking forward to connect! #GSCN

Early career group leaders We appoint researchers from across biology and biomedicine to set up their first groups at the Crick.

The @crick.ac.uk is recruiting Early Career Group Leaders

- Lab set-up, research costs, salaries for up to 5 researchers
- Support for up to 12 years
- Access to our core facilities
- Competitive salary
- Fantastic colleagues
- All areas of biology

Deadline 27 Nov

www.crick.ac.uk/careers-stud...

Berlin Organoid Symposium - News - BIH at Charité The Berlin Organoid Symposium will highlight recent advances in the field, covering topics from fundamental organoid biology to translational applications. By uniting scientists from various instituti...

Tomorrow the first Berlin symposium on organoids will take place @ BCRT/BIH/Charite. Program: www.bihealth.org/en/notices/b....

I will present a summary of our work on liver organoids. : "Everything you always wanted to know about liver organoids (but you were afraid to ask)".

Looking forward to present the work of the lab at the lac leman regenerative medicine symposium: www.habiblab.org/l2rm

Title of my talk: "CELL-BASED THERAPY AGAINST LIVER DISEASES AND BEYOND".

I hope that the "beyond part" got your intrigued, me too.

In late August we had the pleasure of welcoming BSc students from the EPFL in Switzerland. They learned about our IMPRS-BAC graduate program and enjoyed a tour of the institute and the Vallier lab with Maïa Pesic.
We wish the students all the best in their future careers!
@vallierlab.bsky.social

🚨 Job Alert: we seek a Lab Manager for @juliabatki.bsky.social's new group (start Mar 2026), which will study cell fate regulation during organ development. Join the Batki's group to drive experiments & lab operations! Apply at: www.fmi.ch/education-ca...

Berlin Organoid Symposium - News - BIH at Charité The Berlin Organoid Symposium will highlight recent advances in the field, covering topics from fundamental organoid biology to translational applications. By uniting scientists from various instituti...

So, we (Dylan Liabeuf and Anastasiia Maksiuk) are organising the first Berlin symposium on organoids. The objective is to bring together the Berlin organoid community and to develop further interactions.

Info:
www.bihealth.org/en/notices/b...

Free registration:
www.bihealth.org/en/news/even...

Pathway to Independence – an interview with Anzy Miller

Here, @anzymiller.bsky.social talks about about her research interests at the intersection of developmental biology and modelling, as well as her advocacy for inclusivity and sustainability in science.

journals.biologists.com/dev/article/...

The website and the report for the German National Strategy for Gene- and Cell-based Therapies is now available:

www.nationale-strategie-gct.de/en/

If you want to know how Germany will develop these key therapies.

Interested in how cells read biological time? Next week I'm talking about my recently published work on how protein expression oscillations are read by cells and their impact on the timing of cell differentiation. Link below to register!

Looking forward to join the 10th International Symposium on Primate Research in Kunming from the 15th to 18th of August.

The title of my talk:

Fibrosis: developmental biology breaking bad.

New data showing importance of dev mechanisms in disease.

mm.sciconf.cn/en/minisite/...

Check out the latest publication of @vallierlab.bsky.social.
Editor's Choice at DMM Journal (@dmmjournal.bsky.social), Laëtitia Pinte's PhD work highlights the role of EHF in the airway epithelium. Congrats and thank you to all co-authors!

Very good news. Vital for European research especially with the increase in applicants and the recently announced augmentation of grant size. Success rate must be maintained above 10% and should be above 20%. This is the only way to maintain faire system supporting broadly impactful research.

Horizon Europe 2028 - 2034: twice bigger, simpler, faster and more impactful Research and innovation news alert: As part of the next long-term EU budget 2028-2034, the Commission is proposing to double the budget of the research and innovation framework programme to €175 billi...

Very promising news on the next seven-year EU budget, with a proposed substantial increase for Horizon Europe including the ERC.

We are analysing the other parts of this proposal in more detail.

@Vonderleyen @EZaharievaEU

research-and-innovation.ec.europa.eu/news/all-res...

The latest publication from @vallierlab.bsky.social is now online. This tour de force from the amazing Laetitia Pinte (supervised by @martavilagonz.bsky.social) uncover the function of EHF in the lung (not a liver story!) epithelium using hiPSCs, genome editing, and lung organoids

Transverse section images of cultures from reporter line stained with Haematoxylin and Eosin.

Read our #DMMEditorsChoice highlight on the Research Article by Laetitia Pinte, @martavilagonz.bsky.social, @jamesnathanlab.bsky.social, @andresfloto.bsky.social, @pcicuta.bsky.social, @vallierlab.bsky.social and colleagues.

doi.org/10.1242/dmm....

Happy national day to all French people!

🇫🇷 & 🇪🇺 In 1950, French Jean Monnet played a crucial role in drafting the Schuman Declaration, which laid the foundations for the creation of the European Coal and Steel Community.

For info about the Council in 🇫🇷→ europa.eu/!kQtCvg

💥 A single infusion into the portal vein of embryonic stem cell-derived pancreatic islet result in 12/12 patients free of severe hypoglycemic and 83% with insulin independence at one year.
However, one death due to the immunosuppressive treatment.

buff.ly/ZI14m2i

📣 Find out all about funding opportunities, grant budgets, competition schedules, and eligibility rules for ERC research funding in the coming year. The 2026 ERC Work Programme has been adopted!

👉 europa.eu/!qhVTkt

New to the ERC? Watch our webinar Thursday 10th July @ 15:00 CEST europa.eu/!3rGdWB

A tremendous loss. Pete Coffey passed away.

Congratulations Anzy for this work and exciting science. Thank you also for the collaboration.

I’m really pleased to share that our paper is out in Developmental Cell! NGN3 oscillates in the developing pancreas and controls the timing of cell differentiation via an incoherent feed-forward motif. For more details check out the comments below and DOI: 10.1016/j.devcel.2025.06.004

📢 Don't miss! Remo Rohs, from the University of Southern California, LA will speak at our #DahlemColloquium!
📜 Structure-based deep learning models for predicting protein-DNA binding specificity
📆 02. JUL, 03:00 PM (CET)
📍MPIMG, Berlin
🔗 www.molgen.mpg.de/events/42283...

ERC backs cutting-edge research with €721 million in funding The European Research Council (ERC) today announced the winners of its latest Advanced Grant competition. The funding, worth in total €721 million, will go to 281 leading researchers across Europe. Th...

Results for ERC advanced grants. UK is back in the lead with 56 funded projects and Germany is second with 35 grants!

Success rate 11%. Hopefully the ERC budget will significantly increase to attract scientists from outside EU.

erc.europa.eu/news-events/...

😎 The FSSCR annual meeting is set to take place in Lyon from November 17 to 19th, 2025. Prepare for an incredible lineup of speakers and an outstanding program!

👉🏻 Organoids, pluripotent stem cells, regenerative medicine pre-clinical models, etc.

buff.ly/B6xYOVv
ABSTRACT deadline extended!

The journey culminated on May 12th, invited by the 𝗜𝘁𝗮𝗹𝗶𝗮𝗻 𝗢𝘂𝘁𝗱𝗼𝗼𝗿 𝗙𝗲𝘀𝘁𝗶𝘃𝗮𝗹, Dylan gave a multidisciplinary talk.
🎙️ Now, the adventure continues with the launch of a multilingual 𝗽𝗼𝗱𝗰𝗮𝘀𝘁 series of exceptional individuals from diverse backgrounds.
🌍 Follow the journey: www.berlin-barcelona.com

Work is a collaboration with @matthewkraushar.bsky.social, @aktast.bsky.social and the MPIMG Service Groups FACS, microscopy, sequencing and mass spec, as well as researchers from Austria, the US and Switzerland. Link to the publication:
www.nature.com/articles/s41...

In @nature.com Yaotian Zhang and @henriniskanen.bsky.social from the Hnisz Lab discovered a micropeptide, the "Killswitch," which alters the physical state of biomolecules in condensates. This tool solidifies dynamic, liquid-like droplets, affecting their function.
--> www.molgen.mpg.de/4884827