Simon Richardson

Simon Richardson

@simonrichardson.bsky.social

Assistant Research Professor and Consultant Haematologist | Researches stem cell biology, epigenetics and drug discovery, specialising in B-ALL | Fellow St Catharine's College, Cambridge

150 Followers 308 Following 31 Posts Joined Aug 2024
3 days ago
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a close up of a feather on a rock with the words `` hello '' written in white letters . ALT: a close up of a feather on a rock with the words `` hello '' written in white letters .

We're seeking to fill two roles: a postdoc and a research assistant. Both will focus on resistance mechanisms in brain tumour models using various approaches (in vivo, spatial omics, CRISPR). Please apply if this aligns with your previous experience!

shorturl.at/hZ6mG

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5 days ago
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Simon's fundraiser for Centre 33 Help Simon Richardson raise money to support Centre 33

Excited and frankly nervous to be running the Cambridge Half Marathon tomorrow morning, having only signed up 4 weeks ago. But proud to be running for amazing Centre 33, which does so much for young people in Cambridgeshire. ๐Ÿ’ช๐Ÿผ www.justgiving.com/page/simon-r...

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2 months ago
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2025 is drawing to a close and what a year itโ€™s been! ๐ŸŒŸ

From growing our community to advancing research and transforming clinical practice, itโ€™s been a year full of progress.

Here are some of our 2025 highlights. ๐Ÿ‘‡

Season's greetings to all our members, partners and supporters!

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3 months ago
Research Associate (Huntly Lab - Fixed Term) We are seeking a postdoctoral Research Associate to work on an exciting new multi-disciplinary project studying B-cell acute lymphoblastic leukaemia (B-ALL). The project is a collaboration between Dr

Brian Huntly and I are looking to recruit a postdoc to investigate a promising novel therapeutic target in B-ALL @scicambridge.bsky.social. This new CRUK-funded project will involve collaboration with Prof Sir Steve Jackson's group @cruk-ci.bsky.social and the CRUK Functional Genomics centre.

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3 months ago
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Delighted to help @crukpolicy.bsky.social promote their #BackTheBreakthroughs campaign in Parliament today. Wide-ranging discussions, including on crucial work to reduce regulatory hurdles for trials, improve access to new therapeutics and support clinical academics.

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3 months ago
Research Associate (Huntly Lab - Fixed Term) We are seeking a postdoctoral Research Associate to work on an exciting new multi-disciplinary project studying B-cell acute lymphoblastic leukaemia (B-ALL). The project is a collaboration between Dr

Brian Huntly and I are looking to recruit a postdoc to investigate a promising novel therapeutic target in B-ALL @scicambridge.bsky.social. This new CRUK-funded project will involve collaboration with Prof Sir Steve Jackson's group @cruk-ci.bsky.social and the CRUK Functional Genomics centre.

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4 months ago
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A decade of progress and impact - Leukaemia UK This October marks ten years since Leukaemia UK launched its John Goldman Fellowship (JGF) programme. In this blog, and the next, weโ€™ll explore its impact and successes.

A decade of bold ideas, brilliant minds & real impact. ๐Ÿ’ก

Our John Goldman Fellowships are driving progress in leukaemia research, from identifying new drug targets to repurposing existing medicines.

Read more: www.leukaemiauk.org.uk/stories/a-de...

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5 months ago
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On my way back from a fabulous day of science and catching up with friends and colleagues at the UKALL Research Network update day. Great to see so much progress. ๐Ÿ‘

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5 months ago
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It is with great sadness that the University shares the news of the death of Professor Sir John Gurdon, founder of the @gurdoninstitute.bsky.social

Read our tribute to the visionary Nobel Laureate and watch an interview from 2012, just after he won: https://bit.ly/4mM8o3r

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5 months ago
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Great to host our new @stcatharines.bsky.social medics before their first college dinner ๐Ÿฉบ๐Ÿ˜ท๐Ÿš‘๐Ÿฉปโš•๏ธ

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5 months ago
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Thank you @leukaemiauk.bsky.social for the invitation to #WCD2025. ๐Ÿ˜‹ It was great to share some of our work and humbling to hear the story of 4 year old Billie the Brave. Congrats on raising so much in one evening for life changing leukaemia research! โค๏ธ

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6 months ago

Thanks to @leukaemiauk.bsky.social for the opportunity to contribute to this amazing session. So important to link patient experiences with our science and translational research

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7 months ago
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The Finlay Family Bursary for Scottish undergraduates We are proud to offer this bursary to encourage Scottish students to apply for, and take up, the offer of an undergraduate place at St Catharineโ€™s โ€“ an opportunity which would normally involve greater financial cost than attending a Scottish university.

๐Ÿ’™ Between now & the UCAS application deadline on 15 Oct, itโ€™s worth checking if you're eligible for the Finlay Family Bursary, which covers all tuition fees & a living allowance for a St Catharineโ€™s student from Scotland for all 3 or 4 years of an undergraduate degree: shorturl.at/K0RuE 3/3

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7 months ago
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LS, an emergent form of acute leukemia relapse after antigen-targeted therapy, primarily in B-ALL, has dismal outcomes. buff.ly/59xI6qv #hemesky

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7 months ago

Congrats! Really exciting work.

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7 months ago

I feel a student granulomatous round of unknown aetiology coming on.

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7 months ago
Research Associate (Fixed Term) - Job Opportunities - University of Cambridge Research Associate (Fixed Term) in the Department of Physiology, Development and Neuroscience at the University of Cambridge.

Iโ€™m looking for a Postdoc to join my new lab @pdncambridge.bsky.social on an MRC-funded project and explore maternal inter-organ communication with a focus on the mammary gland, using a novel mouse model.

๐Ÿ“ Tenure: 3 years
โณ Deadline: 15 August 2025

Please RT ๐Ÿ™
๐Ÿ‘‰ www.jobs.cam.ac.uk/job/51984/

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8 months ago
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No trains? No problem! Wacky races down to The City of London with these amazing @crukcamcentre.bsky.social entrepreneurial scientists just in time for the CRUK Innovation and Enterprise awards. Thank you @crhorizons.bsky.social ๐Ÿฅ‚๐ŸŽ‰๐Ÿ™

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8 months ago
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Absolute honour to attend Marc Mansourโ€™s @marcmansour.bsky.social inaugural lecture at ICH today. An inspiring clinician scientist and all round legend. #researchculture

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8 months ago

Fabulous news Geula. Congratulations!! ๐Ÿฅ‚

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8 months ago
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Really exciting to co-organise the 20 year graduation reunion for Oxford medical school last night. Wonderful to reunite with old friends and hear retired DoS Tim Lancaster speak powerfully about how caring is at the heart of good medicine ๐Ÿ’Šโค๏ธ

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8 months ago
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Best night of the year !

Farewell dinner for the new doctors from @stcatharines.bsky.social

Interviewed them 7 years ago.
Watched them blossom for 6 years.
Now theyโ€™re amazing!

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9 months ago
Editors' Highlights | Nature Communications Editors' Highlights

Thanks to the editorial team @natcomms.nature.com for including our recent paper in their Editors' Highlights in the field of Cancer Biology ๐ŸŽ‰

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9 months ago
Two charts present survival rates for childhood leukemia over time, specifically focusing on Acute Lymphoblastic Leukemia (ALL) and Acute Myeloid Leukemia (AML). 

In the top panel, for ALL, a series of curved lines represent overall survival rates plotted against years since diagnosis. The lines show a marked increase in survival rates from the late 1960s, when only 14% of children survived more than five years post-diagnosis, to around 94% in the 2010s. Key intervals are labeled, with different colors indicating different periods of diagnosis, ranging from 1972-1975 to 2010-2015.

The bottom panel illustrates survival rates for AML, which are consistently lower overall compared to ALL. Like the top graph, it features several colored lines indicating specific periods. The highest point noted indicates a survival rate of 65%. The graph captures trends in survival as well, showing gradual improvement over time, from 1975-1977 up to 2011-2017.

Data sources for these visualizations are cited at the bottom: Mignon Loh et al. (2023) for ALL and Todd M Cooper et al. (2023) for AML, both from the Children's Oncology Group. The chart is published by Our World in Data, and licensed under Creative Commons by the author, Saloni Dattani.

I wrote a new piece on how much progress has been made in treating childhood leukemia.

The answer is: quite a lot!

Before the 1970s, fewer than 10% of children diagnosed survived 5 years after diagnosis.

Now most are cured and around 85% survive that long.
ourworldindata.org/childhood-le...

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9 months ago
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What an inspiring evening hearing from patients, researchers and fundraisers at an Evening with Leukaemia UK.

So much progress. So much to do
@leukaemiauk.bsky.social

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9 months ago
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Dual drug approach shows promise against childhood cancer On the B-ALL...

Thanks to Chris Smith and the Naked Scientists for the invitation to discuss our work - fully clothed ๐Ÿค“

www.thenakedscientists.com/articles/int...

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9 months ago
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And thatโ€™s a wrap. 20 supervisons in biochemistry and genetics for the Catz @stcatharines.bsky.social first year medics. Good luck in the exams!

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9 months ago

12/12 Special thanks to the patient donors and samples from VIVO Biobank and of course Brian Huntly & group ๐Ÿค— #CSCI @crukcamcentre.bsky.social | Work in my group is largely funded by Cancer Research UK #CRUK, Leukaemia UK
@leukaemiauk.bsky.socialโ€ฌ and the European Hematology Association. ๐Ÿ™๐Ÿป

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9 months ago

11/12 Lots of thanks for help with this multidisciplinary project, including to stellar PhD Alicia Garcia-Gimenez and RA Jon Ditcham for all their hard work | to amazing collaborators @koulman.bsky.social @mitoredox.bsky.social @marcmansour.bsky.social

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9 months ago

10/12 Excitingly, the CREBBP inhibitor Inobrodib has already been tested in combination with Venetoclax in AML, confirming safety. We therefore think this could be a novel, safe, oral approach that could complement current chemo- and immunotherapies, improving outcomes and reducing toxicity.

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