AnneWe

60 submissions to this year's ARTxSCIENCE Competition, showcasing the work done by stem cell scientists in reNEW laboratories

#ARTxSCIENCE2025 - When #science meets art and reveals ongoing #stemcell research with the potential to transform the lives of people with so far incurable diseases. See all the beautiful entries and cast your vote for your favorite before September 22nd: renew.science/artxscience/

13.09.2025 10:56 — 👍 1    🔁 1    💬 0    📌 0

Mapping early human blood cell differentiation using single-cell proteomics and transcriptomics Single-cell transcriptomics (scRNA-seq) has facilitated the characterization of cell state heterogeneity and recapitulation of differentiation trajectories. However, the exclusive use of mRNA measurem...

We’re excited to present this integrative analysis of single-cell proteomics and transcriptomics of the human HSPC hierarchy. Now published in @science.org together with @fabiantheis.bsky.social, @erwinschoof.bsky.social, @porsebo.bsky.social.
www.science.org/doi/10.1126/...
🧵

22.08.2025 06:02 — 👍 50    🔁 14    💬 2    📌 1

It’s always a bit awkward to write about personal experiences. I tried to touch on what Pride means to me and ended up reflecting on heteronormativity, passing, and allyship. Thank you @slefkopoulos.bsky.social for the great opportunity! @ucph.bsky.social
#LGBTQIA+ #PRIDE #Diversity

15.07.2025 04:17 — 👍 42    🔁 9    💬 1    📌 0

α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...

💫NEW: @jzylicz.bsky.social & co show that dimethyl α-ketoglutarate enhances the production and functional maturation of human #trophectoderm - like cells from embryonic #StemCells by regulating histone acetyltransferase activity and the pluripotency network.
bit.ly/3EGflmL

09.05.2025 19:54 — 👍 21    🔁 6    💬 0    📌 0

TCA cycle rewiring underpins implantation and histone acetylation programming Metabolism has emerged as a key regulator of stem cell differentiation and their epigenomes. This coupling is particularly evident during the exit from naive pluripotency in vitro. However, our unders...

In a new preprint with @trabelink.bsky.social, T. Moritz & @bonalditiziana.bsky.social, we find that implantation leads to rewiring of the TCA cycle to support histone acetylation turnover and exit from naïve pluripotency. Gr8 work of @elenikafkia.bsky.social D. Pladevall-Morera et al. rb.gy/clk8vm

29.04.2025 07:54 — 👍 22    🔁 5    💬 4    📌 0

α-Ketoglutarate promotes trophectoderm induction and maturation from naive human embryonic stem cells - Nature Cell Biology Van Nerum et al. show that dimethyl α-ketoglutarate enhances the production and functional maturation of human trophectoderm-like cells from embryonic stem cells by regulating histone acetyltransferas...

Can metabolism regulate more than bioenergetics during human development? Our new study says YES! We show that metabolism influences cell fate choice in human naïve pluripotent stem cells, histone acetylation, and trophectoderm maturation. rb.gy/spqr9j
@natcellbio.nature.com

24.04.2025 06:57 — 👍 63    🔁 18    💬 6    📌 2

Please RT: We are still looking for computational and/or hybrid candidates to join the lab as PhD students. Topics on Alzheimer's Diseases, cell communication and aging. e-mail me if you are interested #joboffer #PhDposition #BCN #scRNAseq

18.02.2025 14:21 — 👍 5    🔁 7    💬 0    📌 1

Only 2 weeks left to apply! 16 fantastic positions available, also @ucph.bsky.social . For our project remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.

03.03.2025 16:07 — 👍 2    🔁 2    💬 0    📌 0

We're hiring a motivated PhD student! Join reNEW @ucph.bsky.social & @nucleardn.bsky.social to study how metabolism regulates chromatin & stem cell fate thanks to generous Marie Skłodowska-Curie Fellowship. Remember to apply both at shorturl.at/yf7Qq & nuclear-dn.eu.

07.02.2025 15:20 — 👍 13    🔁 12    💬 0    📌 1

I’m very excited about this collaborative project! We managed to significantly scale up and streamline human blastoid generation without the use of feeders. @leeboratory.bsky.social @grazianomartello.bsky.social @pasquelab.bsky.social and Nicolas Rivron @ucph.bsky.social

21.01.2025 14:29 — 👍 17    🔁 2    💬 0    📌 0

Finally on Bluesky. Running late as usual. (Plagiarizing part of my first tweet from 2015.)

23.01.2025 10:24 — 👍 2    🔁 0    💬 0    📌 0