Marie Binvignat

Inducible protein degradation reveals inflammation-dependent function of the Treg cell lineage–defining transcription factor Foxp3 Acute Foxp3 protein depletion selectively affects Treg cells responding to type 1 inflammation.

Recently in #Science #Immunology: Van der Veeken & al @ IMP @viennabiocenter.bsky.social generated 🐁 w auxin-inducible degradable #Foxp3! Tissue #Tregs minimally unaffected @ homeostasis but highly dependent on continuous Foxp3 activity in models of #autoimmunity, #viral #infection, & #cancer !

🚨 NEW 🚨

🤩 This month's Editors Choice (Clinical) is about intestinal health and hand #osteoarthritis

Read more from @mbinvignat.bsky.social @jeremiesellam.bsky.social - www.oarsijournal.com/article/S106...

Molecular endotypes and theratypes in osteoarthritis: transforming a concept into reality with deep learning and multiomics Osteoarthritis (OA) is now understood as a heterogeneous disease in many respects, including its clinical presentation, underlying pathophysiological mechanisms, and response to treatments. Distinct p...

Check out our new editorial on molecular endotypes and theratypes in osteoarthritis with @jeremiesellam.bsky.social, just out in Annals of the Rheumatic Diseases

ard.eular.org/article/S000...

@crsa-paris.bsky.social @sorbonne-universite.fr

UCSF Scientist Receives High Honor for Exceptional Career Researcher and campus leader Atul Butte, MD, PhD, has been recognized for his outstanding career in the computational and health sciences with induction into the American Academy of Arts and Sciences,...

We’re proud to celebrate @atulbutte.bsky.social on his election to the American Academy of Arts and Sciences, one of the nation’s oldest honor societies. A leader in biomedical data science, his work is reshaping how we diagnose and treat disease. tiny.ucsf.edu/CUz7gN

Serum intestinal permeability biomarkers are associated with erosive hand osteoarthritis and radiographic severity: results from the DIGICOD cohort To investigate the association between intestinal permeability alteration and erosive hand osteoarthritis (EHOA).

Happy to share our new article on Intestinal Permeability serum biomarkers in Erosive hand OA with @jeremiesellam.bsky.social @larhumato.bsky.social @enkrnita.bsky.social and team

Read the paper here: www.oarsijournal.com/article/S106...

@crsa-paris.bsky.social @oacjournal.bsky.social