Irene Beusch

rest in power @weinberz.witchlab.org one of the coolest women and scientists I have ever met.

Calling all Jr RNA Scientists: We are recruiting 2 new RNA Society Jr Sci Reps to lead existing and new initiatives for engaging junior members over the next two years! Details for submitting applications below. @rnasociety.bsky.social

Super cool to see where this went since the last conference poster I saw! Congrats to Sierra and you all!

Are you interested in studying RNA phages? We are looking for a PhD student and a postdoc to join the lab!

For more information and how to apply, see below 👇

Please RT!

mRNA initiation and termination are spatially coordinated Transcriptional initiation and termination decisions drive messenger RNA (mRNA) isoform diversity but the relationship between them remains poorly understood. By systematically profiling joint usage o...

Thrilled to share our work on transcription initiation and termination being spatially coordinated out today in Science! www.science.org/doi/10.1126/...

Research Affiliate I (Post Doctoral) Applications to be submitted by October 13, 2025 Compensation Grade: P99 (Research Affiliate I) Compensation Details: Minimum: $62,353.20 - Maximum: $62,353.20 Annually Positions with a designated wor...

My lab is hiring a postdoc! Official job ad and application instructions here:

healthresearch.wd1.myworkdayjobs.com/en-US/HRI_Ca...

Current deadline says October 13, but this will be extended to be open for ~2 weeks.

We have an open post-doc position in my group to study mRNA cleavage and polyadenylation using biochemical reconstitution and cryoEM.

Please get in touch if you are interested in joining this amazing team! 🔬🧬🤩
#RNA #cryoEM

Love RNA biology?

Join us to explore the piRNA pathway with structural and genetic approaches (see 👇👇).

PhD student/postdoc position co-supervised by Clemens Plaschka & myself.

DM or email us if you’d like to know more!

@vbcscitraining.bsky.social @imbavienna.bsky.social @impvienna.bsky.social

PhD position in Gene Regulation Are you excited about studying the crucial process of transcription? Join our supportive, young and growing team!

As part of this grant, I have a vacancy out for a PhD student to join our super nice team. It closes on September 9 (Tuesday).
If you are or know a good prospective PhD student, excited about studying transcription, please (suggest them to) apply here: www.uu.nl/en/organisat...

congratulations Hanneke!!! Looking forward to all the cool science coming out of this!!!

Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!

U-rich elements drive pervasive cryptic splicing in 3’ UTR massively parallel reporter assays - Nature Communications Massively parallel reporter assays (MPRAs) are powerful technologies for measuring the impact of non-coding sequences on gene expression. Here, the authors demonstrate that MPRA reporters often underg...

Our collaboration with Tony Mustoe's lab us out today. MPRA libraries and possible cryptic splicing in MPRA reporters, or reporters in general. The additional novelty here is that such events are controlled or influenced by AU-rich sequences.

www.nature.com/articles/s41...

Pervasive noise in human splice site selection RNA splicing has historically been thought to be highly efficient and accurate, with little opportunity for deviation from regulated alternative splicing decisions. This dogma has been challenged by r...

New from the Pai lab @rti-umasschan.bsky.social

www.biorxiv.org/content/10.1...

I guess your(?) bike has some privileges? 😉🥲

Deadline for applications is this Friday!!!

The IncaRNAto lab is seeking a motivated #PhD candidate, interested in studying #RNA structural ensemble dynamics in living cells. Here's the link to the vacancy: www.rug.nl/about-ug/wor.... Please share!

Phenotypic landscape of an invasive fungal pathogen reveals its unique biology The construction and high-precision fitness profiling of a C. neoformans knockout library reveals a high-resolution functional map of its genome and allowed for the identification of fungal analogs of...

My postdoctoral work with @hitenmadhani.bsky.social is now online at @cp-cell.bsky.social! We profiled the fitness of >4300 Cryptococcus neoformans deletion strains in >140 conditions, identifying unexpected mammalian-like biology and drivers of fungal pathogenesis.

www.cell.com/cell/fulltex...

„AI is unavoidable, and even if a single query is low-impact, governments and companies are now shaping a much larger energy future around AI’s needs.“

U1 snRNP regulates alternative promoter activity by inhibiting premature polyadenylation Kim et al. uncover a role for U1 snRNP in regulating internal promoter activity. Beyond its canonical role in splicing, U1 snRNP suppresses premature polyadenylation, enabling upstream transcription t...

Very excited to share our new paper out now in
@MolecularCell. We show how U1 snRNP -a well-known splicing factor- regulates the activity of alternative promoters in human cells www.cell.com/molecular-ce...

congrats Mike!!! 🎊 I am looking forward to all the cool science from your lab!

Congrats Dr. Love! 🎊

Flyer for the 2025 Next Generation Faculty Symposium (including QR code in top right corner). This symposium highlights the work of exceptional early-career scientists in the broad field of quantitative biological and biomedical sciences, with a track record of excellence in research, leadership, mentorship, and community engagement. These early career scientists are preparing to launch a faculty search. Applications are due May 30th, 2025.

Hello Community!
Are you a postdoc/grad student preparing to launch a faculty search? Do you have a track record of excellence in research, leadership, mentorship & community engagement? Apply to the 2025 Next Generation Faculty Symposium: www.berkeleystanfordnextgensymposium.com! Pls repost! (1/3)

5-ethynyluridine perturbs nuclear RNA metabolism to promote the nuclear accumulation of TDP-43 and other RNA binding proteins TDP-43, an essential nucleic acid binding protein and splicing regulator, is broadly disrupted in neurodegeneration. TDP-43 nuclear localization and function depend on the abundance of its nuclear RNA...

5EU labelling may have some undesired consequences or effects depending on labelling pulse concentration & duration www.biorxiv.org/content/10.1... #RNAsky

Are you a postdoc ready for transition to an independent position? You connect infection biology with cutting-edge structural biology or multimodal imaging? Are you aware of such a colleague?

I am seeking speakers for "The Next Generation in Infection Biology" microsymposium on June 6 2025.

Tissue-specific splicing prediction – What’s in a name, what’s in a claim, and are target functions all the same? In today’s blog post, I want to discuss some work/claims related to a topic that has been one of my lab’s focus areas – predicting tissue-specific alternative splicing (AS) of RNA. Some backg…

Interesting blog post by Yoseph Barash on tissue specific splicing prediction: biociphers.wordpress.com/2025/04/09/t...

Our PhD program application deadline is near, apply now! In our open present call, we have 25+ fully funded positions for talented Master/MSc students. Start your application by 11 April 2025
training.vbc.ac.at/p...

Two reminders for aspiring PhD candidates: April 3 is the information session, and April 11 is the application deadline. See below for more info.

loved the pre-print. looking forward to reading the final manuscript!

Work With Us The LIT welcomes individuals from all life paths and academic backgrounds. If you are passionate about science we could be the perfect home for you.

I’m looking for a BTA and a Postdoc to help set up the Structural Biochemistry group at the Leibniz Institute for Immunotherapy (LIT) in Regensburg 😀.

We apply synthetic biology and protein design to address key challenges in immunotherapy.
lit.eu/work-with-us/
#SynBio #ProteinDesign #Immunotherapy

Cool „news“ from the Hoskins Lab! 🤩 Looking forward to reading them!