GGNBP2 regulates MDA5 sensing triggered by self double-stranded RNA following loss of ADAR1 editing
GGNBP2, CNOT10, and CNOT11 are required for innate immune response after the loss of ADAR1-mediated editing of self dsRNA.
Time for a 🧵 on our new paper from the Walkley lab in @scienceimmuno.bsky.social.
If you're into RNA editing by ADARs, double-stranded RNA (dsRNA) sensing, post-transcriptional gene regulation and CRISPR screening, then read on! 1/X
www.science.org/doi/10.1126/...
#RNASky #ImmunoSky
06.12.2024 01:31 — 👍 49 🔁 15 💬 4 📌 0
Home | Mukherjee Lab
Santa Cruz RNA Center Seminar
“Surveilling ribosomes to target and dissect translation in human disease”
Dr. Neel Mukherjee
Assistant Professor, Biochemistry & Molecular Genetics, University of Colorado School of Medicine www.mukherjeelab.org
Tuesday, November 26th, 2024
26.11.2024 06:24 — 👍 8 🔁 1 💬 0 📌 0
Beyond Active learning
How not to be a passive instructor in an active classroom.
Active learning can take many forms, but all require students to actively participate rather than passively absorb content. Typically, this involves structured activities such as group work, guided worksheets, think-pair-share, gallery walks, and jigsaw activities.
open.substack.com/pub/allthing...
18.11.2024 17:00 — 👍 1 🔁 1 💬 0 📌 0
A picture of Dr. Crystal Rogers from UC Davis pointing to an I Voted sticker.
Who am I if I’m not a #DevelopmentalBiologist? A (long) thread. Today on my re-introduction to BlueSky, I would like to tell you how I got here. I am a #FirstGen college attendee and graduate. I was raised in a single-parent household. We struggled financially when I was growing up. 1/
09.11.2024 15:13 — 👍 161 🔁 32 💬 5 📌 6
An ancient competition for the conserved branchpoint sequence influences physiological and evolutionary outcomes in splicing
Shout out to former labbie Sam Fagg now Asst Prof at UT Galveston on his lab's publication in Elife - the branch point consensus sequence bound by SF1 is ~same as the QKI recognition site. WUT? Turns out the two proteins been fighting for years!
elifesciences.org/reviewed-pre...
09.11.2024 06:08 — 👍 1 🔁 1 💬 0 📌 0
Senior research scientist at the University of Texas Southwestern Medical Center (UTSW) in the Center for Alzheimer's and Neurodegenerative Diseases (CAND) in Dr. Marc Diamond's lab. Neuroscience, cell biology, microbiology, virology
Assistant Prof @UCSF Dept of Cell & Tissue Biology studying #neuralcrest & #RNA in development & disease #NewPI Views my own #firstgen She/Her
The goal of the Bay Area RNA Club is to bring San Francisco Bay investigators together to discuss RNA-centric science. #BARC #BARC2024
PhD student at Julius Lukes Lab @BiologyCentre
Studying tRNAs and translation in protists.
Excited about RNA, computation, structural biology, cryoET, splicing. Current: Atomic AI. Previous: in Ellen Zhong's lab, at Stanford with Rhiju Das' lab. she/her
Assistant professor @ Sloan Kettering Institute | Postdoc @ the Marraffini Lab Rockefeller University | PhD @ the Schuldiner Lab Weizmann Institute | microbial defense systems
Scientist, immigrant, mom (she/her)
RNA biologist, climate activist, and forest person. Director of Yale Center for RNA Science and Medicine.
🎥 https://boxd.it/1Ek8z
Science News from Academic Journals etc.
Assistant Professor @IRCM, @McGill Center for RNA Sciences, @UdeM.
RNA Biology, lncRNA, RNA Therapy, Genome Regulation sauvageaulab.org
INSERM researcher and group leader in Lyon 🇫🇷, studying the functions of RNA/DNA helicases 🧬 in gene expression and RNA processing
Group leader @embl.org European Molecular Biology Laboratory
#RNA biology | #single-molecule #biophysics | #structural biology | #biochemistry | #quantitative biology | #chemical biology | #synthetic biology - https://www.embl.org/groups/duss/
Scientist, foodie and dog-lover who enjoys a good hike, long bike rides, and great books; Husband and Father; Formerly a Professor, now Senior Program Director @RCSA, Editor @The Biophysicist.
Steve Mount, Univ. of Maryland.
Interested in gene structure and function, especially pre-mRNA splicing. Bioinformatician and biodata flaneur.
We are interested in life sciences, structural biology, translation, ribosomes, neurobiology and RNA therapeutics.
Location: RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, USA
https://www.umassmed.edu/korostelev-lab/
RNA biologist and virologist @Columbia. Studying how viruses use RNA structure to manipulate cellular processes. She/her
www.steckelberglab.org
Immunologist interested in how the genome works
https://www.babraham.ac.uk/our-research/lymphocyte/martin-turner
@babrahaminst.bsky.social
/ the genome is a zipfile for the transcriptome / immunity /ageing / & the History of Science/ germinal centres
RNA biologist working at Hudson Institute in Melbourne. Interested in intersection of RNA modifications (A-to-I editing), dsRNA structure and RBPs with innate immunity and autoinflammatory disease. She/her.
RNA biologist working on alternative polyadenylation and RBPs, group leader at i3S and lecturer at ICBAS, University of Porto. Mother of two girls.
Maxwell Professor of United States Citizenship at Boston University and Political Theory Editor at American Journal of Political Science. I write about immigration, citizenship, and the politics of time. https://www.bu.edu/polisci/profile/elizabeth-cohen/
RNA decay, RNA sorting, gene expression
