Hannes Hagström

We’re recruiting a PhD student in AI + Cancer Research at Karolinska Institutet!

This is your chance to work in clinical hepatology, multi-omics, and machine learning.

Please share and tag!

lnkd.in/dR5j3cxZ

#PhDPosition #AIinMedicine #CancerResearch #Bioinformatics #KarolinskaInstitutet

New review from researchers at #Karolinskainstitutet! Health inequalities in the Nordic countries: A comparative overview and update

🔗https://doi.org/10.1111/joim.70029

#healthinequality #mortality

New Original Article! Systemic neutrophil activation and N-formyl methionine-formyl peptide receptor-1 signaling define inflammatory endotypes in rheumatoid arthritis-associated lung involvement

🔗https://doi.org/10.1111/joim.70030

#FPR1 #rheumatoidarthritis #interstitiallungdisease #mitochondria

New Original Article to read! Coexisting inflammatory bowel disease in primary sclerosing cholangitis is associated with higher colorectal cancer and transplant risk

🔗https://doi.org/10.1111/joim.70026

#IBD #PSC #colorectalcancer #livertransplant

Reform UK's ex-Wales leader Nathan Gill admits pro-Russia bribery Nathan Gill admits eight charges of bribery while being a Member of the European Parliament.

Nathan Gill is no fringe politician.

He was the leader of the Reform Party and before that UKIP in Wales.

A Brexit Party MEP.

A friend and ally of Nigel Farage, who in 2016 called him:

"terrific," and "as honest as the day is long."

This is a MASSIVE story

www.bbc.co.uk/news/article...

Plague Death in Arizona: 5 Things you Need to Know Yesterday, Coconino County, Arizona reported the death of a man from pneumonic plague.

A man in Arizona just died from pneumonic plague.

Before you freak out, here are 5 things you need to know about plague.

LInk: open.substack.com/pub/epiellie...

Welcome to read the Editor´s Choice in July!

➡️Accumulating understanding that diet, stress, toxins, and infections affect offspring health.

🔗 doi.org/10.1111/joim.20094
👉Also, read the July issue: onlinelibrary.wiley.com/toc/13652796/2025/298/1

#epigenetics #inflammatorymemory

New Review Article to read! Gaucher disease, state of the art and perspectives #gaucherdisease #glucocerebrosidase #lysosomes

🔗Read here: doi.org/10.1111/joim...

<em>Journal of Internal Medicine</em> | Wiley Online Library Click on the article title to read more.

New Editorial! Community prevalence of advanced liver fibrosis in Type 2 diabetes—How big is the challenge? #MASLD #T2D

🔗 doi.org/10.1111/joim...
👉This Editorial comments on: doi.org/10.1111/joim...

Fatty liver – but not liver damage – common in type 2 diabetes Six out of ten people with type 2 diabetes had fatty liver in a new study from Link&ouml;ping University in Sweden. Of these, only a small percentage had developed more severe liver disease. The study...

Read the News Release! Fatty liver – but not liver damage – common in type 2 diabetes | EurekAlert! www.eurekalert.org/news-release...

Clinical Utility of Non‐Invasive Tests for Liver Fibrosis in People Living With Alpha‐1 Antitrypsin Deficiency Severe alpha-1 antitrypsin deficiency (AATD) is a rare genetic condition characterised by low systemic levels of alpha-1 antitrypsin due to its retention in the liver. Consequently, it predisposes in...

New review from us: Clinical Utility of Non-Invasive Tests for Liver Fibrosis in People Living With Alpha-1 Antitrypsin Deficiency. Happy to coauthor with leading experts and led by Joost Boeckmans. Nice start of a new project on AATD using Swedish data.

onlinelibrary.wiley.com/doi/10.1111/...

Our medical staff are donating their own blood to provide life-saving treatment for patients in #Gaza.

Patients that were gunned down while trying to get food.

Food for their families.

Food to live.

We need an immediate #ceasefire, now.

Continuing today! The 19th Key symposium 2025: Planetary Health – connect the dots. What saves the planet saves our health!

19-21 May in Stockholm, Sweden.

Gunhild Stordalen opens today´s program: key-symposium2025.se

#PlanetaryHealth25

Weight loss in MASLD restores the balance of liver fatty acid sources - PubMed BACKGROUNDLipogenesis contributes substantially to the pathological accumulation of intrahepatic triacylglycerol (IHTG) in metabolic dysfunction-associated steatotic liver disease (MASLD). Since hepat...

Pretty cool study

pubmed.ncbi.nlm.nih.gov/40309768/

The May issue is now online!

👉Read our latest articles!

🔗 onlinelibrary.wiley.com/toc/13652796/2025/297/5

#medtwitter #cardiovascular #SGLT2 #diabetes #osteoporosis #Addisson #kidneycancer #hypertension #CKD

The #JSGE @myueg.bsky.social symposium with #lenakristinconradi and @liverepi.bsky.social on using a metabolic switch in #pancreaticcancer for therapy and #MASLD respectively. Truly worth their #risingstar awards!

Tl;dr: Many patients with diagnosed or presumed MASLD will have elevated PEth, suggestive of MetALD/ALD. And, PEth is predictive of liver outcomes. Big thanks to the super talented Juan Vaz for leading this!

⁉️If you are interested in this unique cohort and what can be done, get in touch.

Phosphatidylethanol levels distinguish steatotic liver disease subgroups and are associated with risk of major liver outcomes Phosphatidylethanol (PEth) is an ethanol metabolite used as a specific biomarker for recent alcohol consumption. We aimed to determine the proportion …

🚨New paper from us in Journal of Hepatology - Using PEth values on >50,000 persons to predict outcomes. www.sciencedirect.com/science/arti...

FDA Approves First and Only Therapy for IgG4-RD The CD19+ B-Cell targeted therapy reduced flare risk by 87% in a phase 3 clinical trial.

FDA approves first therapy for IgG4-related disease

www.medscape.com/viewarticle/...

#GastroSky #MedSky #RheumSky

Grant for recruiting international visiting researchers to Sweden The purpose of the grant is to provide higher education institutions and other research organisations the opportunity to develop and strengthen a research field by recruiting a distinguished researche...

Are you a researcher active outside of Europe who might consider coming to Sweden? Check out this @vetenskapsradet.bsky.social grant for recruitment of international visiting researchers!
www.vr.se/english/appl...

7. Den smarta naturen – Peter Stenvinkel - Sommar & Vinter i P1 Utmaningarna vår värld står inför tycks oändliga. Men tänk om det inte är så? I detta Sommarprat får vi lära oss hur vi med hjälp av forskning, naturens ...

Vote for Peter Stenvinkel as a "Sommar" radio show host: www.sverigesradio.se/artikel/kand...

Would be such a nice experience!

Socioeconomic inequalities in diagnostics, care and survival outcomes for hepatocellular carcinoma in Sweden: a nationwide cohort study Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. This study evaluates how strongly socioeconomic factors assoc…

New from Juan Vaz in our group: www.sciencedirect.com/science/arti...

In >5400 patients with primary liver cancer (HCC), those with lower socio-economic parameters such as income levels have more advanced tumors at diagnosis, less frequently receive curative treatments and have poorer prognosis.

Cause-specific mortality in 13,099 patients with metabolic dysfunction-associated steatotic liver disease in Sweden Data on cause-specific mortality in metabolic dysfunction-associated steatotic liver disease (MASLD) are limited. We aimed to determine the rate and risk of death from different causes in patients wit...

New paper from us in @jhepatology.bsky.social: www.journal-of-hepatology.eu/article/S016...
Causes of death in >13,000 persons with #MASLD - check it out #liversky. So proud of co-senior author Axel Wester and first author medical student Gabriel Issa for the work!

Love it!

Population perspectives on benefits and harms of screening for metabolic dysfunction-associated steatotic liver disease - PubMed Screening for diseases can have psychological impacts, such as anxiety, and requires acceptability from the population to be effective. This study examined the perspectives on the benefits and harms o...

Interesting study from Alina Allen's group: pubmed.ncbi.nlm.nih.gov/40105977/

Reassuring that MASLD diagnosis identified through screening led to weight loss and no major issues with increased anxiety.

No issues here!
Good luck to all applicants…. 🙏🏻

<em>Journal of Internal Medicine</em> | Wiley Online Library Click on the title to browse this issue

April number of @jinternmed.bsky.social now out: onlinelibrary.wiley.com/toc/13652796...

Have you secured your spot for #EASLCongress 2025 on 7-10 May?

🌍Join us in Amsterdam or online to transform liver care worldwide! easlcongress.eu/2025-registr...
📜The deadline to submit your late-breaker abstract is TODAY, 17 March! easlcongress.eu/2025-abstrac...

Simultaneous liver transplant and sleeve gastrectomy provides durable weight loss, improves metabolic syndrome and reduces allograft steatosis - PubMed LTSG results in sustained weight loss, resolution of diabetes and hypertension, and reduced recurrence of steatosis and possibly fibrosis compared to LT alone. It confers no increase in mortality or g...

Simultaneous liver transplant and sleeve gastrectomy provides durable weight loss, improves metabolic syndrome and reduces allograft steatosis: pubmed.ncbi.nlm.nih.gov/40089069/

Interesting. Time for a RCT?

#liversky @jhepatology.bsky.social