Jeremy Day's Avatar

Jeremy Day

@daylab.bsky.social

Neuroscientist at UAB interested in molecular and genetic mechanisms in brain function. Director, UAB Comprehensive Neuroscience Center.

2,110 Followers  |  594 Following  |  193 Posts  |  Joined: 09.09.2023  |  1.7907

Latest posts by daylab.bsky.social on Bluesky

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A Common Iba1 Antibody Labels Vasopressin Neurons in Mice There are a wide variety of commercially available antibodies for labeling microglial cells based on different protein targets, as well as antibodies for the same protein target made in different spec...

PSA for all #microglia lovers: certain Iba1 antibodies (see our new paper below for details) label not only microglia, but also vasopressin neurons, at least in mice. Brain region and species matter. A friendly reminder to always validate your antibodies! πŸ”¬

www.eneuro.org/content/13/2...

03.02.2026 21:36 β€” πŸ‘ 22    πŸ” 11    πŸ’¬ 3    πŸ“Œ 1

Excited to share newly minted PhD Anu Korukonda's tour de force thesis work describing the impact of pathogenic tau on #locuscoeruleus function in a mouse model of early #Alzheimers. A must for #BlueSpot researchers! www.biorxiv.org/content/10.6...

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02.02.2026 13:12 β€” πŸ‘ 28    πŸ” 13    πŸ’¬ 2    πŸ“Œ 0
NOT-OD-26-020: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Notice of Temporary Extension to Early-Stage Investigator (ESI) Eligibility Period NOT-OD-26-020. OD

🧡Good news out of #NIH today.
(1) NIH is extending #ESI and #K99/R00 eligibility to accommodate researchers whose eligibility would have ended during the previous shutdown. Take a look at NOT-OD-26-020. If your ESI status would have ended in 2025, you get an automatic extension through 2026/03/31.

30.01.2026 19:34 β€” πŸ‘ 57    πŸ” 53    πŸ’¬ 1    πŸ“Œ 1

Congratulations, awesome work!

24.01.2026 14:50 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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We could all use some extra stress #resilience rn. But how does it work in the brain? On the surface, resilience looks like ignoring stress. Does the brain fail to respond? Or are active adaptations required? Or are resilience and susceptibility divergent paths? doi.org/10.1016/j.celrep.2025.116867

24.01.2026 13:14 β€” πŸ‘ 60    πŸ” 19    πŸ’¬ 6    πŸ“Œ 0

It was definitely at a transition point, even when I was applying. Other programs paid for full travel, lodging in the nicest local hotel. Quite a contrast. I do think that perspective students should get a lot more time with the current students on an interview.

23.01.2026 23:22 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

I interviewed at one university where I slept on the fold-out sofa in a graduate student's apartment. I don't think any expenses were covered.

23.01.2026 23:03 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Biological insights into schizophrenia from ancestrally diverse populations Nature - Genome-wide association studies incorporating data for populations of African ancestry provide an expanded view of the genetic basis of schizophrenia, which has previously been studied...

Now out in @nature.com: Biological insights into schizophrenia from ancestrally diverse populations.

@sinaibrain.bsky.social @sinaigenetics.bsky.social cs.bsky.social @timbigdeli.bsky.social #CDNeurogenomics #MountSinaiPsych #MillionVeteranProgram and many collaborators
Read: rdcu.be/eZ7he

21.01.2026 18:58 β€” πŸ‘ 33    πŸ” 13    πŸ’¬ 0    πŸ“Œ 0

The core herpes simplex-1 fusion complex drives cell-to-cell spreading of pathological Tau https://www.biorxiv.org/content/10.64898/2026.01.21.700770v1

21.01.2026 23:15 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
Cartoon zebrafish with green lit-up brain, in well of plate responding to hit molecule.

Cartoon zebrafish with green lit-up brain, in well of plate responding to hit molecule.

Drug discovery for nervous system disorders is really challenging. We think early/rapid in vivo testing with zebrafish will accelerate the drug development cycle for conserved targets. Check out our proof-of-principle pilot study and virtual drug discovery pipeline (tinyurl.com/3whr23hs). #Skytorial

21.01.2026 14:47 β€” πŸ‘ 14    πŸ” 8    πŸ’¬ 1    πŸ“Œ 1

Thanks for the invitation Talia, this is a really nice special issue!

19.01.2026 14:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Addiction Neuroscience | Dopamine circuitry and heterogeneity in addiction | ScienceDirect.com by Elsevier The heterogeneity of midbrain dopamine neurons is coming into focus. Distinct subtypes of dopamine neurons can be identified across the ventral tegmental area (VTA) and substantia nigra pars compacta ...

I edited a special issue of Addiction Neuroscience on dopamine circuitry & heterogeneity in addiction - now complete!🧠πŸ§ͺ

Check out the full issue & my editorial (all open access) here: www.sciencedirect.com/special-issu...

19.01.2026 14:11 β€” πŸ‘ 68    πŸ” 22    πŸ’¬ 2    πŸ“Œ 0

Honored to have made the frontal cortex (cingulate?) of @npp-journal.bsky.social reviewers this year!

16.01.2026 21:26 β€” πŸ‘ 12    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

TF-MINDI is out! A new method to learn cis-regulatory codes through rich embeddings of TF binding sites. TF-MINDI decomposes motif neighbourhoods, and works downstream of any sequence-to-function deep learning model. We deeply study the enhancer code in human neural development, check out the thread

15.01.2026 12:32 β€” πŸ‘ 59    πŸ” 38    πŸ’¬ 1    πŸ“Œ 0
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System-wide extraction of cis-regulatory rules from sequence-to-function models in human neural development The genomic cis-regulatory code (CRC) underlies spatiotemporal specificity of gene expression. While sequence-to-function (S2F) models can accurately encode the CRC of transcriptional enhancers, decod...

Check out the preprint: doi.org/10.64898/202... and the TF-MINDI package: github.com/aertslab/TF-MINDI. With @lukasmahieu.bsky.social ’s help this has become an amazing and user-friendly package, please give it a try and provide feedback.

15.01.2026 11:56 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

Don’t know what was more thrilling, the Atlantis water slides #ACNP2026 or the high-speed Bahamian roundabouts on the way to and from the airport. Great meeting with great people and I’m already excited for next year.

15.01.2026 23:51 β€” πŸ‘ 17    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Congrats to all, lots of familiar names on this list!

15.01.2026 14:49 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Congrats to the new @acnporg.bsky.social Fellows! #ACNP2026

15.01.2026 13:28 β€” πŸ‘ 38    πŸ” 10    πŸ’¬ 0    πŸ“Œ 0

Banned from travel to #ACNP2026 at the last minute, the NIH Institute Directors will join the meeting via remote. Koob, Volkow and Acting Director Beckel-Mitchener for NIAAA, NIDA and NIMH.

12.01.2026 18:04 β€” πŸ‘ 24    πŸ” 13    πŸ’¬ 1    πŸ“Œ 0

Congratulations Keri!

09.01.2026 13:50 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

If you are submitting an NIH grant in February, you will be required to use SciENcv to prepare you biosketch.

IT IS MUCH WORSE THAN YOU CAN POSSIBLY IMAGINE.

Set aside *at least* 4 hours just to transfer an existing an biosketch into SciENcv.

06.01.2026 23:29 β€” πŸ‘ 178    πŸ” 93    πŸ’¬ 27    πŸ“Œ 28
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Now they are trying flattery to make me forget about how slow the NCBI site is...

06.01.2026 18:41 β€” πŸ‘ 11    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
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I am just bummed to see Alabama incorrectly listed second in the alphabetized states list when entering appointments! If you type "AL" it will enter Alaska for you.

06.01.2026 18:14 β€” πŸ‘ 7    πŸ” 1    πŸ’¬ 2    πŸ“Œ 1

Have heard this too, apparently a political appointee at HHS has terminated approval at the last minute despite travel plans being approved months ago and conference costs already paid.

05.01.2026 22:08 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 2    πŸ“Œ 0

🧠 We're hiring! 🧠 Are you passionate about neuroscience and education? Join our faculty at UNC Chapel Hill to inspire and teach the next generation of neuroscientists. Apply now: πŸ”—β€‹β€‹https://unc.peopleadmin.com/postings/308455

#Neuroscience #TeachingJobs #AcademicJobs #HigherEd

09.12.2025 19:20 β€” πŸ‘ 33    πŸ” 50    πŸ’¬ 3    πŸ“Œ 0

Is this kind of information in the Delta app?

03.12.2025 20:11 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

The first one is not a test of replicability. It is a test of generalization. It is important to stop conflating these.

03.12.2025 16:08 β€” πŸ‘ 38    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1
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Jobs | Psychological & Brain Sciences Tenured/Tenure-track position in Cognitive Psychology Open Date Dec 01, 2025 Salary Range or Pay Grade The expected academic base salary range for this position is $110,000- $144,500 (Assistant Profes...

Department of Psychological & Brain Sciences at Johns Hopkins is inviting applications for 3 open-rank tenured/tenure-track positions in (1) Behavioral Neuroscience, (2) Cognitive Neuroscience, and (3) Cognitive Psychology.

pbs.jhu.edu/about/jobs/

02.12.2025 00:00 β€” πŸ‘ 71    πŸ” 58    πŸ’¬ 0    πŸ“Œ 1

New computational paper from the lab! Thanks to the reviewers for helping us improve this paper from the preprint version and Nucleic Acids Research for a smooth publication process.

26.11.2025 18:15 β€” πŸ‘ 22    πŸ” 5    πŸ’¬ 0    πŸ“Œ 1
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Ventral tegmental area GABA neurons integrate positive and negative valence - Nature Communications The role of ventral tegmental area GABA neurons in behavior is unclear. Here, authors show that VTA GABA but not dopamine neurons integrate positive and negative valence to encode motivational conflic...

So excited to see our latest paper out today in @natcomms.nature.com! Studies led by the amazing @margestelzner.bsky.social www.nature.com/articles/s41.... VTA GABA neurons have a unique role in economic decision making - they integrate reward seeking motivation and the current cost of seeking

24.11.2025 16:18 β€” πŸ‘ 117    πŸ” 26    πŸ’¬ 6    πŸ“Œ 1

@daylab is following 20 prominent accounts