Quentin Perrenoud

We are happy to announce our new preprint:
“Slow Intrinsic Oscillations in the Ventrolateral Preoptic Nucleus”
We identify <1 Hz rhythmic bursting in #VLPO neurons that persists under TTX, revealing intrinsic oscillatory mechanisms that may shape NREM #sleep dynamics.
www.biorxiv.org/content/10.1...

(8/8) To sum it up, event-based analysis powerfully captures the dynamics of gamma activity in the visual cortex. Gamma events support visual integration and occur at a flexible rate according to context and behavior. We look forward to seeing more developments of event-based analysis in the future

(7/8) Gamma event rate increases during visually guided responses and suppressing gamma events during a task decrease visual detection performance

(6/8) Most visually evoked spikes happen during gamma events! The more events you get during a visual stimulus, the more spikes you get as well

(5/8) Events are suppressed if we turn off the visual thalamus. Conversely events can be evoked by short activation of thalamic terminals

(4/8) Gamma events rate is modulated by arousal and locomotion. You get more events when a mouse is awake and active and more narrow band gamma power

(3/8) Narrow band power around 55Hz is caused by events patterning in bursts. Distributed events yield power in the broader gamma range (30-80Hz). So, gamma is an oscillation … but not always

(2/8) Using a new method: CBASS (github.com/cardin-higle...) we establish that gamma power can be linked to specific translaminar network events. Events can occur in oscillatory bursts or in isolation but maintain consistent dynamics throughout

Flexible perceptual encoding by discrete gamma events - Nature Using a new analytical method for tracking gamma band events in mouse visual cortex, flexible encoding of visual information according to behavioural context is shown.

(1/8) My latest study is out in @nature.com ! Kudos to coauthors especially @jess-cardin.bsky.social and to @kavliatyale.bsky.social and @wutsaiyale.bsky.social for support. We find that gamma power in mouse visual cortex is caused by brief events of visual processing www.nature.com/articles/s41...