PlanetaOptimism

And what will he leave with? With an additional 10% of tariffs for the whole world? He no longer looks like a clown, but much worse. Si will wipe his boots on him. And Donny will talk about "12 out of 10"...

Southern Russia is facing one of its heaviest drone attacks yet with some 105 drones, 15 jet UAVs and 5 aerostats reported in the air DroneBomber says citing Russian monitoring channels.

Are obesity drugs causing a severe complication? What the science says The United Kingdom and Brazil have issued warnings about a possible link between GLP-1 weight-loss drugs and pancreatic inflammation, but the connection is murky.

The potent GLP-1 drugs are taken by millions of people worldwide to counter obesity, diabetes and more. However, a rare and potentially fatal illness that might be linked to these blockbuster therapies is now causing alarm in some countries.


go.nature.com/4kLBj8D

Brain-derived ketone bodies can replace glucose to power neural function https://www.biorxiv.org/content/10.64898/2026.02.19.706813v1

Supreme Court strikes down most of Trump's tariffs in a major blow to the president The decision does not affect all of Trump's tariffs but invalidates those implemented using an emergency law.

The SCOTUS verdict on tariffs:
"The ruling was authored by Chief Justice John Roberts, who was joined by three liberal justices and two fellow conservatives, Justices Neil Gorsuch and Amy Coney Barrett, in the majority".
Against: Thomas, Alito & Kavanaugh.
www.nbcnews.com/politics/sup...

#caturday

Cellular Senescence Drives Zinc Accumulation and Transporter Dysregulation in Intestinal Epithelial Cells https://www.biorxiv.org/content/10.64898/2026.02.19.706872v1

Left: Probiotic strain abundance quantification in two probiotic intervention trials. Top left: Based on qPCR data, there was a significant enrichment in Akkermansia muciniphila and Bifidobacterium infantis probiotics in Validation Study A at Week 12 compared to Week 0. There was no enrichment of Clostridium beijerinckii, Clostridium butyricum, and Anaerobutyricum hallii probiotics. Bottom left: Based on shotgun metagenomic data, there was significant enrichment in Enterocloster bolteae, Flavonifractor plautii, Sellimonas intestinalis, and Clostridium symbiosum in Validation Study B at Week 12 compared to Week 0. Only E. bolteae and F. plautii showed notable enrichment above the relative abundance threshold of 0.005. Right: Switching from a low- to high-fiber diet in the Arivale cohort causes non-uniform shifts in MCMM-predicted butyrate production. Simulating a dietary shift from a low-fiber standard European diet (blue points) to a high-fiber diet (red points) results in a non-uniform increase in butyrate production across the study population (N = 1,786). Points from the same individual are connected by a horizontal gray line.

#Prebiotic & probiotic interventions can induce therapeutically relevant shifts in your #microbiome, but their effects vary. @gibbological.bsky.social &co show that metabolic models can predict #probiotic engraftment & shifts in SCFA production after intervention @plosbiology.org 🧪 plos.io/4asmMuV

#caturday

First the Justice Department hangs his portrait on a building. Now Florida. What's next? Orwell wrote his "1984" about Britain. But for some reason, "Big Brother" is made in the USA.

Today Ukraine honors the Heavenly Hundred, 107 people killed during the 2014 Revolution of Dignity when the Yanukovych regime shot protesters demanding a European future. Their sacrifice drives Ukraine's fight for sovereignty to this day.

Ukraine's SBU and police with Moldovan partners busted a Russian hit squad planning assassinations of journalists, military officers and public figures. Agents were split into surveillance and kill teams. Russia offered up to $100,000 per target.

Orwell wrote "1984" about this.

Diet modulates metabolic and hepatic responses to chronic pesticide mixture exposure in mice https://www.biorxiv.org/content/10.64898/2026.02.18.705565v1

Gérard Depardieu sera jugé en appel en novembre pour des agressions sexuelles sur le tournage des «Volets verts» L’acteur de 77 ans avait été condamné en mai à 18 mois de prison avec sursis pour des faits d’agressions sexuelles sur une décoratrice et une assistante de réalisation en 2021.

⚖️ Gérard Depardieu sera jugé en appel en novembre pour des agressions sexuelles sur le tournage des «Volets verts»

EN DIRECT, guerre en Ukraine : la Russie « sacrifie 156 hommes pour s’emparer d’un kilomètre » du territoire ukrainien, affirme Volodymyr Zelensky Lors d’un entretien avec le journaliste britannique Piers Morgan, mercredi, le président ukrainien a répété la nécessité pour son pays d’obtenir de solides garanties de sécurité, estimant que « personne ne peut assurer » que Vladimir Poutine ne lancera pas une nouvelle offensive contre l’Ukraine.

EN DIRECT, guerre en Ukraine : la Russie « sacrifie 156 hommes pour s’emparer d’un kilomètre » du territoire ukrainien, affirme Volodymyr Zelensky

💥 A drone strike set a Russian oil depot ablaze despite defenses.

🔗 united24media.com/latest-news/...

Engineering a cytochrome P450 O-demethylase for the bioconversion of hardwood lignin https://www.biorxiv.org/content/10.64898/2026.02.18.706646v1

North Korea tension: US 'armada' was not sailing to Korean peninsula The Carl Vinson strike group sailed in the opposite direction despite US statements, it has emerged.

What war are you talking about? He is TACO... 2017 :
www.bbc.com/news/world-a...

In wartime Ukraine, the government is deploying a super app for the citizenry's future Digital transformation and reskilling are challenges during the best of times, but Ukraine's wartime achievements are a unique form of success under fire.

In wartime Ukraine, the government is deploying a super app for the citizenry's future

Belgium summons U.S. ambassador over post accusing officials of antisemitism The clash over an investigation into suspected unlicensed ritual circumcisions underscores heightened tensions between the U.S. and Europe under President Trump.

Belgium summoned the U.S. ambassador after he published posts on social media accusing officials of antisemitism over an investigation into Jewish religious figures suspected of carrying out circumcisions without required medical training.

Vitamin D deficiency alters prostate epithelial differentiation and increases prostate cancer aggressiveness in ex vivo and in vivo models https://www.biorxiv.org/content/10.64898/2026.02.16.700850v1

Zebrafish screen of schizophrenia risk genes reveals convergent dysregulation of cholesterol metabolism https://www.biorxiv.org/content/10.64898/2026.02.17.706411v1

A rescue team departed for the site of an avalanche in a backcountry area of California's Sierra Nevada mountains where a group of skiers was stranded. Officials later said six surviving skiers were evacuated, and that nine were still missing.

Multimodal antioxidant and anti-inflammatory activity of Rauwolfia serpentina root extracts in experimental models https://www.biorxiv.org/content/10.64898/2026.02.14.705924v1

Meanwhile, Greece and Malta have expressed doubts regarding sanctions against a port in Indonesia.
www.bloomberg.com/news/article...

Russia presses demands, and faces pressure, as Ukraine talks move to Geneva High casualties and economic trouble signal time is no longer on Russia’s side, but Moscow isn’t backing off political and territorial demands to weaken Ukraine.

The Kremlin is intent on forcing Kyiv to bow to demands that would undermine Ukrainian President Volodymyr Zelensky’s hold on power, but as Russia’s invasion of Ukraine nears its four-year anniversary, time no longer appears to be on Moscow’s side.

Circulating saturated fatty acids and incident chronic kidney disease: a meta-analysis of de-novo prospective cohort investigations Chronic kidney disease (CKD) is a global health problem which is associated with poor outcomes, and its prevalence is expected to increase. Identifyin…

In a meta-analysis of 18,193 participants across 9 countries, we observed no indication that SFA increased CKD risk, whereas higher 18:0 concentrations were associated with a lower risk of CKD.

What Trump wants from Russia

A U.S.-Russia arrangement in which Ukraine is little more than a bargaining chip risks hollowing out this project before it is consolidated.