Andrei Thomas-Tikhonenko

Senate committee endorses NIH budget increase, rebuking Trump administration’s proposed 40% cut Senators from both parties endorsed a $400 million increase to the budget of the National Institutes of Health on Thursday

This just in…

FY’26 Bill Highlights:

National Institutes of Health: $48.7 billion for biomedical investments in research.

Cancer: $7.4 billion for the National Cancer Institute, including $28 million for the Childhood Cancer STAR Act.

www.statnews.com/2025/07/31/n...

31.07.2025 22:36 — 👍 2    🔁 1    💬 0    📌 0

I wonder if anyone else was just spending his/her Super Bowl weekend reviewing grants and at ~7 pm of Saturday saw eRA Commons go dark. Not to be paranoid or anything…

09.02.2025 01:37 — 👍 1    🔁 0    💬 0    📌 0

Neuronal cell adhesion molecule (NRCAM) variant defined by microexon skipping is an essential, antigenically distinct, and targetable surface proteoform in high-grade glioma To overcome the paucity of known tumor-specific surface antigens in pediatric high-grade glioma (pHGG), we contrasted splicing patterns in pHGGs and normal brain samples. Among alternative splicing ev...

A project three years in the making finally sees the light of day. Microexons meet macroglia… cancerous macroglia meet engineered T cells (at your peril). Joint venture with @hagentilgner.bsky.social @yosephbarash.bsky.social et al @childrensphila.bsky.social www.biorxiv.org/content/10.1...

17.01.2025 01:56 — 👍 1    🔁 1    💬 0    📌 0

Dropped From Spending Bill, Cancer Research and D.C. Stadium Measures Revived by Senate (Gift Article) Two bills on pediatric cancer research and a football stadium site had been left out of the main spending package, but passed early Saturday as separate legislation.

This is both public and personal... our latest NIH grant was funded through Gabriella Miller Kids First Research Act... every dollar is re-invested into pediatric cancer research - and real jobs for real people! www.nytimes.com/2024/12/21/u...

22.12.2024 02:04 — 👍 1    🔁 0    💬 0    📌 0

Not every week starts on a bad note… TGIM!

18.12.2024 01:10 — 👍 4    🔁 0    💬 0    📌 0

One oral and one poster presentations from the ATT lab at #ASH24 in always-sunny San Diego. Cancer immunotherapy through the lenses of RNA metabolism, population genetics, and racial disparities @ash-hematology.bsky.social @pennmedicine.bsky.social

06.12.2024 18:18 — 👍 4    🔁 0    💬 0    📌 0

Thank you!

22.11.2024 19:51 — 👍 1    🔁 0    💬 0    📌 0

Steering research on mRNA splicing in cancer towards clinical translation - Nature Reviews Cancer Although splicing factors are altered in cancer through mutations and copy number variations, their exact role remains challenging to define. In this Roadmap, Anczukow, Thomas-Tikhonenko and colleague...

For my first post here, I unveil the just-published definitive version of our NRC Roadmap article, where we argue that “widespread splicing alterations [is a] readily actionable feature of human cancers”. Grateful to Forbeck Foundation for bringing this group together! www.nature.com/articles/s41...

22.11.2024 19:31 — 👍 3    🔁 0    💬 1    📌 0