Every organism's research community aspires to have a resource like FlyBase. Letβs help!
03.06.2025 17:35 β π 7 π 3 π¬ 0 π 1
Research Fellow: Immune system and Cognitive function
Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing & Alzheimerβs using iPSC models, genomics & molecular biology
Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing and Alzheimerβs, using iPSC models, genomics, and molecular biology @ukdri.ac.uk @dervissalih1.bsky.social Closing date: 26th June
www.dementiaresearcher.nihr.ac.uk/job/research...
31.05.2025 21:38 β π 14 π 18 π¬ 0 π 1
A multimodal screening platform for endogenous dipeptide repeat proteins in C9orf72 patient iPSC neurons
Repeat expansions in C9orf72 are the most common cause of amyotrophic lateral sclerosis and frontotemporal dementia. Repeat-associated non-AUG (RAN) tβ¦
We tagged C9orf72 repeat dipeptides in patient iPSC-neurons and did genetic and small molecule screens with interesting results! Huge effort from many lab members @ukdri.ac.uk⬠@uclqsion.bsky.social and @alzheimersresearchuk.org⬠Drug Discovery Institute at UCL www.sciencedirect.com/science/arti...
28.05.2025 14:29 β π 6 π 5 π¬ 1 π 0
Thank you Nayanika! πβ€οΈ
03.03.2025 22:49 β π 0 π 0 π¬ 0 π 0
Thank you Fabio!! π
27.02.2025 08:33 β π 1 π 0 π¬ 0 π 0
Thank you Sarah!
27.02.2025 08:12 β π 1 π 0 π¬ 0 π 0
Thank you Sara!
27.02.2025 07:43 β π 0 π 0 π¬ 0 π 0
Thank you Selina!!
26.02.2025 19:34 β π 0 π 0 π¬ 0 π 0
Thank you Darragh! π
26.02.2025 19:34 β π 1 π 0 π¬ 0 π 0
Thank you to Alzheimer's Research UK and the Jean Corsan foundation for this incredible recognition! I am so grateful to ARUK for the continued support throughout my PhD and beyond!
26.02.2025 18:47 β π 16 π 1 π¬ 6 π 0
Neuronal polyunsaturated fatty acids are protective in ALS/FTD
Nature Neuroscience - Lipidomics revealed that neurons of patients with ALS/FTD have reduced levels of polyunsaturated fatty acid (PUFA)-containing phospholipids. Increasing neuronal PUFA levels...
Really excited this is out! We found polyunsaturated fatty acids (PUFAs) were beneficial in models of C9orf72 FTD/ALS and the greatest benefit occurred when increasing levels specifically within neurons @ukdri.ac.uk @uclqsion.bsky.social @ucl.ac.uk @cziscience.bsky.social
rdcu.be/ebbZf
25.02.2025 13:31 β π 47 π 24 π¬ 2 π 3
Shurl and Kay Curci Fellow of the Life Sciences Research Foundation | Postdoc scientist with Lori Passmore at the MRC LMB | Biochemistry PhD with Judith Kimble and Marvin Wickens | Lover of all things RNA.
Operated by @shervinnia.bsky.social and inspired by the now-defunct bot by FrΓ©dΓ©ric Poitevin and @gati.bsky.social. Suggestions welcome.
Web Developer #Joomla | Beekeeper | Former Grave Digger | Widow
Disabled USMC Vet | Living with #DDD & #MS
Sarcastic AF - blame the MS or the Marines π€·π½ββοΈ
π MS Sucks: a snarky journal for tracking your MS bullshit β mssucks.co/links
Media Relations Manager at Blood Cancer UK. All things research communications, celebrity ambassadors and newsy! Ex Alzheimer's Research UK. Proud Northerner. Sub-par cricketer
Neuroscientist at the Roskamp Institute | Tau pathology, ApoE, Astrocytes, Blood-brain barrier, Alzheimerβs disease, Traumatic Brain Injury.
https://orcid.org/0000-0002-1967-9450
Professor of Pathology at the University of Cambridge. Equalities Fellow, Welfare Tutor and Director-of-Studies at St Catharine's College. Educator, scientist, immunologist, daddy. Founder and CSO of Aila Biotech Ltd.
Developmental neurobiologist using cerebral #organoids to study brain size and evolution. Opinions my own.
Stem cell researcher | fighting dementia | UCL London
The Collaborative Computational Project for electron cryo-microscopy (CCP-EM) supports users and developers in biological EM.
CCP-EM is based at STFC and core funded by MRC both of which are part of UKRI
https://www.ccpem.ac.uk/
The Lister Institute of Preventive Medicine funds high quality biomedical researchers through annual prize grants.
Group Leader at the Rosalind Franklin Institute. In situ imaging/cryo tomography of complex biological systems.
MRC-funded group leader at UCL Queen Square Institute of Neurology studying peripheral nerve diseases to develop targeted gene therapies #CMT #ALS #SMA #AxonalTransport | he/him
Neurobiologist @UCLIoN. Interested in neurons, intracellular trafficking and local translation.
Assistant professor in the School of Basic Medical Sciences, Peking University
MRC-LMB #cryoET #biofilms #S-layers #antibiotics
https://www2.mrc-lmb.cam.ac.uk/groups/bharat/
Group Leader @MRC_LMB /Structural Biologist/Biochemist. Amateur baker in free time #RNAworld #spliceosome #telomerase #telomeres #cryoEM #Xraycrystallography
cellarchlab.com Univ. of Basel Biozentrumπ¨π. Exploring molecular architecture inside cells with #CryoEM #TeamTomo. Plants and algae in a changing climate. βπ¬ OF πΏ 4THE π!
Cellular structural biology (cryo-EM/ET, CLEM, biophysics) | nature, society, sport and fatherhood | Group Leader at MRC_LMB | https://www2.mrc-lmb.cam.ac.uk/group-leaders/a-to-g/matteo-allegretti/
Joint Head of Structural Studies at @mrclmb.bsky.social. Develops & uses #cryoEM to study amyloids in neurodegeneration. #tau, #alphasynuclein, #opensoftware, #RELION. All opinions my own.