Paula Tirado

El próximo sábado 27 de septiembre estaremos hablando de la #enfermedadRara #SyndromeLambShaffer con las familias de los pacientes. Encuentro abierto a científicos, médicos y familiares de pacientes.
Nos vemos allí!
@institutocajal.bsky.social @csic.es @rarascsic.bsky.social 🧬🧠

Very happy to wrap up #SENC2025 presenting my poster. Thank you all for coming. Being located next to @paulatiradom.bsky.social has been really fun (and useful for adult neurogenesis enthusiasts!)

📢 If you are a fun of #neuraldevelopment and #neurodevelopmentaldisoderes you shouldn't miss this exciting Symposium at #SENC2025 Friday the 5th 9:00am with Silvia Capello, Daniel del Toro, Antonella Consiglio
and more. See you there ! @institutocajal.bsky.social
@csic.es @idibaps.bsky.social

Only one day left until #SENC2025 ! ✨ Don't miss our poster on hippocampal neurogenesis 🧠 on Friday session from 15.00 to 18.30 S05-13.

🧬Un gen clave en el desarrollo embrionario protege la reserva de células madre en el cerebro adulto

🔬 La investigación del @institutocajal.bsky.social-#CSIC revela una ventana temporal después del nacimiento, crítica para establecer una neurogénesis adulta duradera

➡️ http://tiny.cc/iovq001

New neurons are generated throughout adult life in the adult neurogenic niche in the hippocampus through activation of reversibly quiescent neural stem cells (NSCs). The cover highlights DCX+ immature neurons (blue) in the hippocampal dentate gyrus of a conditional mutant mouse for Sox5, with recombined Sox5 deficient cells in magenta. Medina-Menéndez et al. report that Sox5 is required to control the correct establishment of quiescence during the first postnatal weeks of dentate gyrus development, which is essential for establishing long-lasting adult neurogenesis. https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002654

Ever wondered how adult #NeuralStemCells develop and acquire their lifelong potential?
Excited to share our latest work on the origin of #AdultNeurogenesis by Cris Medina
@paulatiradom.bsky.social Lingling Li & @pilar-rguezm.bsky.social now in @plosbiology.org🧪🧠
@institutocajal.bsky.social
👇🧵

So happy to see this one finally out! Have a read if you are interested in adult neurogenesis and neural development ✨🧠🧪

Our new work on the establishment of quiescence in #adultneurogenesis , done at @institutocajal.bsky.social @csic.es, is out in @plosbiology.org .
Proud of a Great team, Cristina Medina,
@paulatiradom.bsky.social , Lingling Li , @pilar-rguezm.bsky.social and the rest ! 🎊🎉🧠

💥 We are very proud of our last paper now plublished in @plosbiology.org ! Really thorough study of how NSCs acquire quiescence during early postnatal stages by @aixa-v-morales.bsky.social lab. Great job @paulatiradom.bsky.social 💪. Congrats!

Genetic evidence that our brains make new neurons in adulthood may close a century-old debate Cells from human brain tissue have genetic hallmarks of neural progenitors, AI-aided study finds

Can an adult brain make new neurons? I break down how an AI-powered study may finally settle one of neuroscience’s longest-running debates & what questions still remain for @science.org

www.science.org/content/arti...

🧠✨ Imagen del mes | Hipocampo en desarrollo
Esta región del cerebro, clave para la memoria, sigue generando neuronas en la adultez. En el Instituto Cajal, Paula Tirado investiga cómo se forman y regulan las células madre que lo hacen posible. Descubre más aquí https://tr.ee/7hDKcM

This week we welcome on campus 2025 class of students for our hands-on Stanford Brain Organogenesis course.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.

A partir de mañana ya se podrá visitar la expo en el mercado de san Fernando

www.instagram.com/p/DH347yItD6...

Mi amiga y artistaza @mateohenar.bsky.social ha preparado una exposicion de ilustraciones inspiradas en el trabajo de mujeres científicas y he tenido la gran suerte de que me incluya 💜👩🏻‍🔬✨ Podéis disfrutarla desde ya en Madrid o en su web ⬇️ retratodelamujerenciencia.my.canva.site

A lo mejor, algún día, el #8M deja de celebrarse porque se han cumplido todas sus reinvindicaciones y ya no es relevante.

Mientras eso no sea así, habrá que insistir, en la ciencia, en el trabajo, y en cualquier lado.

Feliz #diainternacionaldelamujer

En un #28F de hace 2 años escribí un pequeño hilo en Twitter para hablar de una enfermedad rara que, cada día, lo es un poco menos: el síndrome de Lamb-Shaffer. ¿Os parece si hacemos un poco de mudanza y me lo traigo a Bluesky? 📦
⬇️ Aquí viene un poco de copia-pega

A black and white face-like image with large buggy eyes. In the middle there is a small heart-shaped structure with tendrils coloured in a variety of colours like purple, red and yellow.

This is an image of a living zebrafish embryo with the heart visible, labelled with fluorescent proteins and taken using confocal #microscopy 🧪🔬

Image credits: Rashmi Priya and Srinivas Allanki