Tara Sutherland

Research points to new treatment target for asthma A new way to treat asthma symptoms and even repair previously irreversible lung damage could be on the horizon following the discovery of a potential new therapeutic target by Foundation-funded Dr Tara Sutherland and a team of scientists at the University of Aberdeen.

A new study from @drtesutherland.bsky.social (@uniofaberdeen.bsky.social) suggests future asthma treatments could reverse lung damage.

Funded by @medresfdn.bsky.social + @asthmaandlung.org.uk, this research may transform care for asthma + other fibrosis-linked diseases.💡

📖➡️ https://bit.ly/4mHTOKq

We're looking for a Lead Scientist to join Flow Cytometry Centre in Aberdeen! Fantastic opportunity to deliver services, work with varied research groups, promote cytometry and further develop the facility. Aberdeen is a great place to live/work- APPLY NOW www.abdnjobs.co.uk/vacancy/cyto...

Exciting work by @drtesutherland.bsky.social!
#ScienceImmunology uncovers chitinase like proteins as key drivers of airway ECM remodeling, blocking Ym1 can reverse it!

#Immunology #RespiratoryResearch #SciOpen #TUP

Also big shout out to Morgan Bryant - PhD student @uniofaberdeen.bsky.social for the fantastic image of Ym1+ macrophages amongst a lung ECM remodelled environment that is featured on the Sci Imm website this week

Surprisingly, airway ECM remodelling was protective for lung function, and rather seems to support epithelial function. Huge amount of work by @james-ep.bsky.social @hetompkins.bsky.social and a tremendous amount of help and support from all of our collaborators at Aberdeen and Manchester

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.

Extremely happy to see our work out in #ScienceImmunology. We show allergen-induced ECM remodelling occurs independently of IL-13 or IL-17 driven inflammation. Rather chitinase-like proteins drive airway ECM accumulation & inhibition of Ym1 can remarkably reverse it. www.science.org/doi/10.1126/...

Allergen-induced airway matrix remodeling in mice can be prevented or reversed by targeting chitinase-like proteins Allergic airway matrix remodeling occurs independently of IL-13 and IL-17A and is driven instead by chitinase-like proteins.

Now in #Science #Immunology, @drtesutherland.bsky.social & al report chitinase-like proteins (CLPs) make distinct contributions to airway pathology independent of #IL13- & #IL17 –mediated signaling in 🐀 #asthna model! CLPs orchestrate airway #ECM remodeling, & can be both protective & detrimental!

Aberdeen is hiring - Neuroimmunology Lectureship! Really exciting opportunity to join our supportive, collaborative and multidisciplinary Institute to carry out cutting edge translation research. Not to mention the scenery in the North East of Scotland is amazing www.abdn.ac.uk/jobs/vacanci...

Looking forward to @emds2025.bsky.social in my home town of Edinburgh this week! Will be at poster 48 on Wednesday with our work characterising macrophage dynamics in severe allergic asthma models.

Postdoc Appreciation Week #NPAW2025. We're lucky to have 2 postdocs in our Aberdeen Uni lab @mattoburgess.bsky.social and Dr.Anton. You guys are amazing, innovative, hardworking scientists, and so supportive of everyone and everything that happens in the lab & beyond. Thanks for everything you do!

Patterning of cell identities in the posterior E8.5 mouse embryo. Co-expression of mesoderm marker TBXT (blue) and neural marker SOX2 (green) identifies cells in the neuromesodermal (NMP) progenitor region at the intersection of their respective gene expression gradients. TBX6 (red) marks paraxial mesoderm and also marks sporadic mesoderm-committed cells emerging within the NMP region. LAMINB1 (white) marks the nuclear envelope of all cells. Credit: Matthew French.

Measuring properties of individual cells in relation to their neighbors in 3D tissues is challenging. @cellysally.bsky.social &co develop a computational toolkit to facilitate this, analyzing developmental patterning in mouse, chick & #Drosophila #embryo @plosbiology.org 🧪 plos.io/4lQMeNu

A major KI initiative to recruit new assistant professors with outstanding proposals in all areas of medicine, biomedicine and public health. We offer an amazing research environment, great colleagues and generous startup packages. Check it out and get working on your applications! (repost please!)

Oversimplified immunology is holding biomaterials back - Nature Reviews Bioengineering Immune responses are complex, often defying rigid classifications. Instead of interpreting results according to reductionist categories, researchers should rely on comprehensive single-cell data to guide analysis and should remain open to unexpected immunological complexity.

Immune responses are complex, often defying rigid classifications. The authors of a Comment article in Nature Reviews Bioengineering argue that researchers should rely on comprehensive single-cell data to guide analysis and should remain open to unexpected immunological complexity. 🔒

Who's ready for another @thestemvillage.bsky.social Immunology Seminar Series? If you haven't seen these before, we invite LGBTQ+ immunologists to present online to the wider immunology community. If you'd like to present or attend, please drop a mention below #immunosky 🧪 #academicsky

Cheering on the Lab’s UG Honours student Ronya in the University of Aberdeen rowing race today!

Still time to apply for this truly interdisciplinary BBSRC funded PhD project in Aberdeen with @mdmorgan.bsky.social and myself. Develop computation models to analyse ECM-cell interactions and then test them a lab setting! Deadline 17th Jan

We just can't stop recruiting!

Associate professor in cell and molecular biology @dunnschool, with a preference for immunology, inflammation and/or infection - all defined broadly

Come and be our colleague

Deadline 28 Feb, please spread the word

www.path.ox.ac.uk/vacancy/asso...

Still time to apply to join our lab in Aberdeen as a post-doc, in a well-funded position. If you're interested in immune-ECM cross talk and want to use cutting edge spatial technologies, apply now. www.abdnjobs.co.uk/vacancy/rese...

The image include a picture of immune cells on the right and the words: "30 Jan 2025 Online. Immune responses investigated by spatial biology across species. Brought to you by the BSI Comparative and Veterinary Immunology Affinity Group (CVIG)."

🗓️Three weeks to go until the BSI-CVIG online seminar exploring spatial #omics technologies in #immunology!

🧫 Come along to find out how these advanced technologies can be applied across different tissues and species

Register today👉 bit.ly/423kpJi

#CVIG25

Calendar showing January and a fluorescent microscope image of lung cells

Very pleased to be hanging up the office biolegend calendar for 2025….. very impressed with Morgan (a PhD student from the lab) taking out Jan with one of his many amazing lung confocal images!

Congratulations to Hannah!!! PhD viva done with no corrections. @drtesutherland.bsky.social very proud of her first PhD student. Allen lab is so privileged to have Hannah with us this past 2 years ago.

New year, new job? Work in a great place, with brilliant and supportive people, doing cool stuff….about a week left to apply!

Congrats Ivo! It was great to discuss this exciting project with you. Wishing you all the best for your future career.

We are hiring! Programme Leader Track positions @mrc-lms.bsky.social up for grabs by up-and-coming researchers with a great start to their career who now aim to establish their own group in a translational discovery science institute of world leading excellence. lms.mrc.ac.uk/work/vacanci...

If single cell genomics and quantitative genetics is your thing….check out this PhD project from Mike’s Lab. You’ll get support, an excellent mentor/supervisor and amazing scientist. APPLY NOW

Still cannot believe it’s been nearly a week since I passed my viva 🌟 very proud to be the first Sutherland Lab baby and looking forward to seeing everything the future holds for this wonderful group @drtesutherland.bsky.social

University of Aberdeen , School of Medicine, Medical Sciences & Nutrition PhD Projects, Programmes & Scholarships FindAPhD. Search Funded PhD Projects, Programmes & Scholarships at University of Aberdeen , School of Medicine, Medical Sciences & Nutrition.

If this PhD isn't up your street, check out other fantastic opportunities at Aberdeen for PhDs. It's a great opportunity to work with top scientists in a great environment, and we're a friendly bunch with a great PGR student community www.findaphd.com/phds/school-...

This project also aligns really well to the post-doc position currently open in the lab - www.abdn.ac.uk/jobs/vacanci... to studying ECM-immune interactions in the lung. Get in touch, happy to chat more about these opportunities

Eastbio PhD time! This project is a cracker (not biased at all). ECM-cell cross-talk in the thymus and lung using spatial proteomics & developing computational models to analyse data with the amazing @mdmorgan.bsky.social lab. You'll get support, training and development opportunities. So excited!

PhD examiners and supervisor after a Phd viva

What a journey! So proud of you @hetompkins.bsky.social for getting through the last 4 years and passing your viva (and enjoying it). Thanks for joining the lab way back and being the first graduate of the Sutherland lab.