Buttitta Lab

A window of cell cycle plasticity enables imperfect regeneration of an adult postmitotic organ in Drosophila https://www.biorxiv.org/content/10.1101/2025.06.05.658044v1

Evidence for Transcriptomic Conservation Between the Main Cells of the Drosophila Prostate-Like Accessory Gland and Basal Cells of the Mammalian Prostate. https://www.biorxiv.org/content/10.1101/2025.06.05.658085v1

Thank you for the highlight of our work! #drosophila #cancer model.

Thank you for the highlight of our work! #drosophila #cancer model.

As a “fly person” even I have to admit this is pretty cool! 😎

Proposed cut to NSF Biology budget is 70%.

70%. Seventy.

Call your senators & reps nonstop. Give them numbers on NSF impact for state/district. tableau.external.nsf.gov/views/NSFbyN... explain this will decimate the economy if their districts, especially if it has a major research univ. 🧪

Hi Erik, can we also be added to the feed? sites.lsa.umich.edu/buttitta-lab/

Pleased to share and amplify our most recent paper. Looking at #oncogene effects in the #drosophila #prostate which is #postmitotic and #polyploid. 🧪

Love seeing the cancer cell biology collection @jcb.org! The image they went with for the cover is also pretty great 😜. rupress.org/collection/6...

Wow! This is so cool!

How does one little diploid nucleus contain all of the source for the massive amount of transcription that must take place in this cell!

If using Bloomigton #Drosophila Stock Center stocks, pls. acknowledge them & their NIH funding (P40 OD018537). Papers listing this no. are being harvested as evidence. We massively depend on the @bdsc.bsky.social & they need our support in these dire times! @flybase.bsky.social @fly-eds.bsky.social

Nobel laureate: I owe America my success. Today, its scientific future is in danger | CNN Dr. Ardem Patapoutian says he watches “with deep sadness as the United States’ remarkable scientific enterprise, which took generations of hard work and national investment to build, faces a concerted...

Published an op-ed for @cnn.com: “Nobel laureate: I owe America my success. Today, its scientific future is in danger.”
A personal reflection on what’s at stake as science funding gets slashed. I’d be grateful if you could amplify both in and beyond the science world.
www.cnn.com/2025/04/09/h...

Developmental Biology, the official journal of the SDB, publishes original research on mechanisms of development, differentiation, growth, homeostasis and regeneration in animals and plants at the molecular, cellular, genetic and evolutionary levels.

Why Publish in Developmental Biology?
1/8

Reason #1 - DB is strongly committed to supporting trainees and junior scientists. Publish your first paper with us!

DB is the official journal of the SDB @socdevbio.bsky.social

Learn more here
elsevier.com/locate/ydbio

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature. 1998

Developmental biology research leads to fundamental discoveries for biomedical research.
12/12

RNA Interference. Fire et al., 1998 PMID: 9486653
Worm image by Tokiko Furuta

@socdevbio.bsky.social
@rrbehringer.bsky.social

The “drosophila dress” at #dros25. (For the fly peeps - zoom in on the pattern at the neckline)

Formation and detection of RNA-DNA hybrid molecules in cytological preparations. Proc Natl Acad Sci U S A. 1969

Developmental biology research leads to fundamental discoveries for biomedical research.
5/12

In Situ Hybridization
Gall & Pardue, 1969. PMID: 4895535
Frog image by Brandy Walker (Rachel Miller Lab)

@socdevbio.bsky.social

@rrbehringer.bsky.social

Hi Esther! Great idea! We’d like to be added please!

Underrepresented Populations in the U.S. Biomedical, Clinical, Behavioral and Social Sciences Research Enterprise Individuals from racial and ethnic groups that have been shown by the National Science Foundation to be underrepresented in health-related sciences on a national basis Individuals with disabilities, who are defined as those with a physical or mental impairment that substantially limits one or more major life activities, as described in the Americans with Disabilities Act of 1990, as amended. See NSF data at, https://www.nsf.gov/statistics/2017/nsf17310/static/data/tab7-5.pdf. Individuals from disadvantaged backgrounds, defined as those who meet two or more of the following criteria: Were or currently are homeless, as defined by the McKinney-Vento Homeless Assistance Act (Definition: https://nche.ed.gov/mckinney-vento/); Were or currently are in the foster care system, as defined by the Administration for Children and Families (Definition: https://www.acf.hhs.gov/cb/focus-areas/foster-care); Were eligible for the Federal Free and Reduced Lunch Program for two or more years (Definition: https://www.fns.usda.gov/school-meals/income-eligibility-guidelines); Have/had no parents or legal guardians who completed a bachelor’s degree (see https://nces.ed.gov/pubs2018/2018009.pdf); Were or currently are eligible for Federal Pell grants (Definition: https://www2.ed.gov/programs/fpg/eligibility.html); Received support from the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) as a parent or child (Definition: https://www.fns.usda.gov/wic/wic-eligibility-requirements). Grew up in one of the following areas: a) a U.S. rural area, as designated by the Health Resources and Services Administration (HRSA) Rural Health Grants Eligibility Analyzer (https://data.hrsa.gov/tools/rural-health), or b) a Centers for Medicare and Medicaid Services-designated Low-Income and Health Professional Shortage Areas (qualifying zipcodes are included in the file

Before it is all taken down, a good reminder that the NIH has (or maybe had) an expansive definition of what constitutes diversity. So this means less participation by #womeninSTEM, #URMinSTEM, #disabledinSTEM, plus those that grew up rural, #firstgen, unhoused, or low-income.

#academicSky 🧪👩‍🔬 2/n

Reposting as the deadline to submit draws near.

Thank you for this thread. I was a graduate student at the Carnegie from 1998-2003. Don was the chair of my thesis committee (at that time the chair was not your direct PhD mentor). I often went to him for advice. I fully agree he was simultaneously intimidating and yet empowering.

Drosophila folks, new workshop alert for #dros25:
@gavinrrice.bsky.social and I are organising a workshop on Polyploidy, please consider submitting an abstract by 15 January to shyama.n@pitt.edu
#polyploidy #drosophila

Post-eclosion growth in the Drosophila ejaculatory duct is driven by Juvenile hormone signaling and is essential for male fertility The Drosophila Ejaculatory duct (ED) is a secretory tissue of the somatic male reproductive system. The ED is involved in the secretion of seminal flu…

Finally made it here! Delighted to share our newest paper in #DevBio on #Drosophila. We reveal interesting cell cycle regulation in the #drosophila male reproductive system www.sciencedirect.com/science/arti...