's Avatar

@denby-lab.bsky.social

397 Followers  |  654 Following  |  5 Posts  |  Joined: 21.08.2024  |  1.7595

Latest posts by denby-lab.bsky.social on Bluesky

Check out this great paper for @davidbaird86.bsky.social and our Edinburgh Kidney Team.
Delighted to see the first publication of seNSOR which was a prospective study of CKD patients from Edinburgh and Glasgow to find new non-invasive biomarkers of kidney disease funded by @kidneyresearchuk.org

23.05.2025 10:55 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Profiling of insulin-resistant kidney models and human biopsies reveals common and cell-type-specific mechanisms underpinning Diabetic Kidney Disease - Nature Communications Diabetic kidney disease is the leading cause of kidney failure in the world and cellular insulin resistance is an important driver of this disease. Here, Lay et al identify multiple insulin-resistance...

Transcriptomic and proteomic profiling of insulin resistant kidney cells! TMT proteomics of podocytes, glomerular endothelial, mesangial and proximal tubular cells. Mitochondrial bioenergetics and mechanistic insights of diabetic kidney disease. This has a little something for everyone!

06.12.2024 10:36 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells - Nature Immunology Pyroptotic cell death results in inflammation. Here the authors find that F-actin-rich structures formed during macrophage pyroptosis persist after cell death to activate dendritic cells.

#NoTimeToDie! @inflammasomelab, Holley, Monteleone &co show @natimmunol.bsky.social that cells that die by #pyroptosis, or #necroptosis, are crowned with F-actin filopodia that makes them visible by dendritic cells via CLEC9A to initiate adaptive immunity! www.nature.com/articles/s41...

05.12.2024 16:55 β€” πŸ‘ 59    πŸ” 22    πŸ’¬ 1    πŸ“Œ 1
Lab Christmas tree built from Protector RNase Inhibitor pot, coloured eppendorfs and foil star.

Lab Christmas tree built from Protector RNase Inhibitor pot, coloured eppendorfs and foil star.

Crafting in Lab - we present the Den-way recycled expensive Lab πŸŽ„

04.12.2024 16:53 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

I have had some amazing students, when urine love and all that. Vintage card still goes up #kidney #Christmas

01.12.2024 14:30 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image

🀩🀩 here she is our post-doc star Rachel Bell presenting her data at #EMDS24 . Who does love Mo:Macs and 🫘.

27.11.2024 17:13 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Beautiful room with fabulous artwork on ceiling

Beautiful room with fabulous artwork on ceiling

Poster

Poster

Eek 1st post to say Dr Rachel Bell is currently at #EMDS2024 in Vienna presenting some of our new kidney myeloid cell work. What a venue 😍😍, truly inspiring! If you are there go say Hi to her!

27.11.2024 08:46 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Post image Post image Post image Post image

🎨 In case anyone need…

The NIH BioArt Source is an awesome library of *free* professionally drawn illustrations for scientific presentations or figures. Downloadable in HD. Thank you NIH for this invaluable tool πŸ™!

Check it out πŸ‘‡
bioart.niaid.nih.gov

23.11.2024 15:49 β€” πŸ‘ 1207    πŸ” 494    πŸ’¬ 44    πŸ“Œ 28
Post image


Delighted to share our latest paper:

"The glomerular circadian clock temporally regulates basement membrane dynamics and the podocyte glucocorticoid response"

Expertly led by Rebecca Preston & in collaboration with clock superstar Qing Jun Meng

pubmed.ncbi.nlm.nih.gov/39515644/

Key findings πŸ‘‡πŸ‘‡

21.11.2024 15:39 β€” πŸ‘ 42    πŸ” 12    πŸ’¬ 2    πŸ“Œ 0

@denby-lab is following 20 prominent accounts