John Greally

Yours is the first feedback I have received from someone who has read the whole book, I’m very grateful for the positive impression.

'That's mad, Ted': stamps launched for Father Ted's 25th anniversary Stamps feature phrases from award-winning comedy set on fictional Craggy Island

(The full quotation is "That's mad, Ted")

www.theguardian.com/tv-and-radio...

Sign the Petition Support a New York State Biomedical Institute for a Healthier, More Affordable Future

📢 SIGN & SHARE THE PETITION! 📢

New York needs an Empire Biomedical Research Institute to create new statewide funding opportunities for scientists & physician-scientists so that patients and their families get the life-saving and life-changing new therapeutics they're hoping for ✏️ c.org/TDMy2H9JTW

If you want to read something completely nuts from the unregulated world of direct to consumer genomics, look no further.

And when I say completely nuts, I’m being restrained and polite. Criminal is another word that springs to mind.

Job Opportunities | Ireland’s foremost contemporary music festival New Music Dublin takes place in Spring each year within the National Concert Hall and other venues throughout Dublin.

Hey Bluesky arts/music folks in Ireland! At New Music Dublin we are looking to fill a new role: part-time general manager, working closely with our festival director and producer (& board). Role to commence in Jan. Detailed info here: www.newmusicdublin.ie/job-opportun... #SpeirGorm

This garbage is what we’re up against.

I have seen multiple families who have received ‘stem cell therapy’ for their child with autism and intellectual disability. Not well-off families, probably spending 5-figure sums.

These bottom-feeding influencer scum are preying on the desperate.

I hope you enjoy it, thanks Jacob.

"the possible stigmatization of individuals with these real conditions today" -- exactly why this study is repugnant.

I have patients with this condition, they really do not need to be dealing with this garbage science.

These kinds of publications may be the most valuable today.

Their impact in terms of guiding sensible grant funding investments, manuscript evaluations, and science communications.

Nice work @wiringthebrain.bsky.social and colleagues.

A handy translation guide for non-academic speakers.

Someone should write a book. Oh, wait...

Yes, the bar is getting higher. But we have to get to that level to gain genuine biological insights.

Right now most DNA methylation studies on cohorts are cargo cult science.

Furthermore, if rare variants have such major and cell type-specific effects, it's not enough to know about common variants in the individuals studied.

It's worth stressing the point that those studying #epigenetics really need to be expert in genetics.

These variants are probably also reflected by small DNA methylation differences between individuals.

You can't interpret DNA methylation without knowing about genotype.

Impact of Rare and Common Genetic Variation on Cell Type-Specific Gene Expression Understanding the genetic basis of gene expression can shed light on the regulatory mechanisms underlying complex traits and diseases. Single cell-resolved measures of RNA levels and single-cell expre...

Interesting, from @garvaninstitute.bsky.social.

"We identify putative common regulatory variants for 83% of all 21,404 genes tested and cumulative rare variant signals for 47% of genes...about half of the effects are observed only in one or a few cell types"

www.medrxiv.org/content/10.1...

Irish culture. No apologies.

Thanks Nico! I hope you like it!

Outstanding book, loved it

When I read the history of Waddington, I realized that, in using the epigenetic landscape model, this geology dropout student may have been trolling the field of biology!

www.amazon.com/Epigenetics-...

Relatable

Squllionaires being sold a pig in a poke is just funny. But a child harmed by trash science sold by the unscrupulous is criminal.

What Rosalind Franklin truly contributed to the discovery of DNA’s structure Franklin was no victim in how the DNA double helix was solved. An overlooked letter and an unpublished news article, both written in 1953, reveal that she was an equal player.

On the event of James Watson's death, I highly recommend this 2023 commentary from @matthewcobb.bsky.social and Nathaniel Comfort with crucial new insights into the discovery of the double helix. (And also check out Cobb's brand new biography of Francis Crick) www.nature.com/articles/d41...

I suggest to colleagues that we hold off for the moment from the (valid) criticisms of this individual. A family is in mourning. There will be plenty of time for his history to be written.

He made a massive impact. Respect.

Hot take — could this be a possible clue as to why @zohrankmamdani.bsky.social did so well in the #NYC election yesterday?

IT'S HAPPENING! 💥 I'm psyched to launch the collaboration between @qedscience.bsky.social & @openrxiv.bsky.social @biorxivpreprint.bsky.social! Preprint + q.e.d = your science is out there, and anyone can appreciate it. Let's care about making discoveries, and not on “getting published” (1/3) 👇

People cheering in the streets in the East Village #NYC right now.

📣 I am hiring a postdoc! aial.ie/hiring/postd...

applications from suitable candidates that are passionate about investigating the use of genAI in public service operations with the aim of keeping governments transparent and accountable are welcome

pls share with your networks

Thank you Sandra! I hope you like it.

‘Exododus, movement of Jah Dodos’ as a wise man who knew how to spell never said @nypost.com