John Greally

(With apologies to Theodosius Dobzhansky, and a link to his must-read essay from 1973)

inters.org/files/Dobzha...

Really well put: “The developing organism accretes information as it builds itself.”

Increasingly I am coming around to the perspective that nothing in genetics makes sense except in the light of cell biology.

(In this era of a rampantly prolific ‘wellness’ industry and false claims by charlatans attempting to sell you their garbage products, there is nothing wrong with your refuting nonsense based on your hard-earned scientific and medical insights. Try it)

Myth or Reality—Transdermal Magnesium? In the following review, we evaluated the current literature and evidence-based data on transdermal magnesium application and show that the propagation of transdermal magnesium is scientifically unsupported. The importance of magnesium and the ...

Imagine if our skin was so absorbent that our immersion in liquid caused molecules to enter our bodies.

Clearly it isn’t. Histologically we see stratified squamous epithelium covered in supple shell of keratin.

And that is why Epsom Salts do absolutely nothing:
pmc.ncbi.nlm.nih.gov/articles/PMC...

The US health system. So in need of innovation, so refractory to innovation. But we should keep trying to fix this broken system.

Fascinating proposal for New York State, may now pass the tipping point of feasibility in an era of savage Medicaid cuts.

A vibrant, wide-angle photo of a colorful outdoor mural promoting the "Super Bowl LX Apple Music Halftime Show." The mural is painted on a long blue wall in a sunlit, tropical setting with real palm trees and bright pink bougainvillea flowers cascading over the top. The artwork features a playful, surreal collage of cultural and football-themed elements: Central Text: The Apple Music logo in bold yellow and red 3D lettering is flanked by "SUPER BOWL LX" above and "HALFTIME SHOW" below. Iconic Imagery: Large illustrations of a golden trumpet, pink sunglasses, maracas, dominoes, and a cup of coffee with a musical note in the foam. Football Elements: Brown footballs are depicted growing on palm trees like coconuts and resting on the ground. Foreground: A young girl in a yellow dress walks along the sidewalk in front of the mural, passing a small goalpost illustration where a green parrot is perched. The overall aesthetic is warm, festive, and celebrates a fusion of Latin-inspired culture and American football.

I'm going to do a thread of all the references and context behind Bad Bunny's performance and what it means for Puerto Ricans to see this on the biggest stage.

The opening title screen is a street mural in Puerto Rico that comes to life with footballs as coconuts.

Follow along!

Is the @nytimes.com trolling Gina Kolata?

Relentlessly negative about the medical profession, her headline asks what we physicians are really good for?

The answer is in the second headline — we are really good at medicine. No apologies, not buying into this ridiculous framing.

And we’re the outliers with peculiarities?

Native BioData Consortium | Official Merchandise | Bonfire Check out Native BioData Consortium on Bonfire and shop official merchandise today! Featuring limited edition custom apparel, printed with care in the USA just for you.

The NYTs comment section for our feature yesterday got so heated, they shut it down immediately. However, people want to donate to #IDSov. Here’s ours: www.bonfire.com/store/native... donorbox.org/help-to-empo... www.bonfire.com/store/native... Here’s the movement’s indigenousdata.org nativegov.org

Opinion | The Finance Industry Is a Grift. Let’s Start Treating It That Way.

Gift link www.nytimes.com/2026/02/06/o...

Opinion | The Finance Industry Is a Grift. Let’s Start Treating It That Way.

A conservative economist writing about capitalism today. Fascinating perspective.

www.nytimes.com/2026/02/06/o...

Thanks Scott

He Built a Server to Protect Indigenous Health Data

Maith thú Joe @joseph-yracheta.bsky.social

www.nytimes.com/2026/02/05/s...

Solid genomics and statistical analyses involved, plus some innovative machine learning designed to bring FNCV information to clinical diagnostics.

The postdoc will be embedded with the @newyorkcrd.bsky.social group, who have an interest in getting FNCVs into translational use.

This position has 2 years of funding from SFARI to test our findings that indicate an accumulation of functional non-coding variants (FNCVs) in regulatory loci of glutamatergic neurons causing neurodevelopment disorders.

Please share this with your network: Postdoctoral position available in my group.

www.linkedin.com/jobs/view/43...

Examples of Departmental strengths include model organism researchers (including Hannes Bülow, Bernice Morrow, Meelad Dawlaty, Julie Secombe), ageing research (Jan Vijg) and population genetics (Srilakshmi Raj), and is the home for the research arm of the @newyorkcrd.bsky.social.

Please share: we're hiring a new tenure-track faculty member to our Department of Genetics at Albert Einstein College of Medicine.

faculty-einstein.icims.com/jobs/17847/a...

The goal is to understand how non-coding sequence variation may cause intellectual disability, improving our ability to give families answers when they have a child with this condition.

Anyone interested should reach out to me directly. We will officially post the position soon.

The applicant should have the ability to work with large genomic datasets, and learn/apply statistical and machine learning approaches. They will be co-mentored by Srilakshmi Raj. Start date May 1 2026, we need to fill the position soon. 2/3

Please spread the word — a 2-year postdoctoral fellowship is available in my group funded by the Simons Foundation Autism Research Initiative (SFARI) to perform a study testing the contribution of functional non-coding variants in glutamatergic neurons to autism. 1/3

The term 'junk DNA', used by Susumu Ohno in 1972, has no modern validity over a half century later. This 98.8% of the genome is what regulates gene expression, it's fascinating.

We're using it. Nobody should expect a step forward to complete a long journey, but this is a significant step forward and should be celebrated.

We only understand the 1.2% of the human genome that encodes genes. AlphaGenome is a tool towards understanding the remaining 98.8%.

Advancing regulatory variant effect prediction with AlphaGenome - Nature AlphaGenome, a deep learning model that inputs 1-Mb DNA sequence to predict functional genomic tracks at single-base resolution across diverse modalities, outperforms existing models in variant effect...

We're testing AlphaGenome.

It's a very valuable step forward towards the goal of identifying functional non-coding variants (FNCVs) causing human diseases.

Congrats to @avsecz.bsky.social and the team for this landmark publication.

www.nature.com/articles/s41...

YouTube video by breathinthefreshair360 Grace Jones - Pull Up To The Bumper

RIP Sly Dunbar, hopefully back to jamming with Robbie Shakespeare somewhere beyond the clouds

youtu.be/o_PNL3djy54

You're not ready for grant applications yet, right? Just manuscripts?

A reminder that history is rewritten every day. There is no Irish genome. Irishness is not genetic.

www.bbc.com/sport/athlet...

YouTube video by National Monuments Service The Irish DNA Atlas: providing a map of Irish genetics in and out of Ireland - Dr Edmund Gilbert

Interested in the genetic history of the island of Ireland?

From Edmund Gilbert. Includes relationships with Britain, Vikings, Iceland, and Newfoundland.

youtu.be/m5AwYzzCAF4

Plus this commercial prenatal testing to create "superbabies" is all unapologetic eugenics, disgusting and vile

...who heads the genomics division at New York’s Albert Einstein College of Medicine in addition to his work at a children’s hospital. “These companies are selling a product that only the wealthy can afford, while my patients lack basic resources.”