Jeff Mold's Avatar

Jeff Mold

@jeffmold.bsky.social

American/Swedish Biomedical Scientist studying immunology and cancer. My favorite cell atlases say “here be dragons” on the UMAPs. @karolinska institute https://scholar.google.com/citations?hl=en&user=_owb98cAAAAJ&view_op=list_works&sortby=pubdate

1,566 Followers  |  2,296 Following  |  1,297 Posts  |  Joined: 10.11.2024  |  2.3937

Latest posts by jeffmold.bsky.social on Bluesky

Let those amongst us who have not hoodwinked or bamboozled our fellow man/woman on a dirigible, zeppelin or airship cast the first stones…

10.02.2026 06:26 — 👍 1    🔁 0    💬 0    📌 0
Trump Defends Racist Obama Meme & MAGA Rages Over Bad Bunny’s Spanish Halftime Show | The Daily Show
YouTube video by The Daily Show Trump Defends Racist Obama Meme & MAGA Rages Over Bad Bunny’s Spanish Halftime Show | The Daily Show

This guy is killing it now. youtu.be/vfpQbv7CmeE?...

10.02.2026 06:24 — 👍 0    🔁 0    💬 0    📌 0

Why is it that none of these “elites”can spell? These emails all read like a 12 year olds text messages to their bros

09.02.2026 07:56 — 👍 1    🔁 0    💬 0    📌 0

Maybe it’s one of those programs like the LSD exposure in the 50s and 60s that’s meant to test their ability to remain calm under extremely unpleasant circumstances

07.02.2026 17:09 — 👍 3    🔁 0    💬 0    📌 0

*** over 100 years ago ;)

07.02.2026 16:12 — 👍 6    🔁 0    💬 0    📌 0

And to this day journalists have to drag PIs out of the office to put on lab coats and hold beakers with colorful liquids of unknown origins 😂

07.02.2026 16:00 — 👍 13    🔁 0    💬 1    📌 0

I think I’d want to see evidence of genetic lineage if I got such a thing to review. Guilt by association seems a bit fluffy given all we have learned about the history of tumors 😀

07.02.2026 10:13 — 👍 0    🔁 0    💬 1    📌 0

How do people identify “dormant” cells without genetics? And are we certain that a recurrent cancer isn’t actually the birth of a new cancer from a preneoplastic clonal expansion that gave rise to the initial cancer?

07.02.2026 09:49 — 👍 0    🔁 0    💬 1    📌 0
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Not something you see in textbooks very often: tripolar mitosis.

07.02.2026 08:00 — 👍 1555    🔁 269    💬 50    📌 21
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Concerning the Origin of Malignant Tumours by Theodor Boveri. Translated and annotated by Henry Harris In the year 1902, I tacked onto the results of my experiments on the development of doubly fertilised sea urchin eggs the speculation that malignant tumours might be the consequence of a certain abnor...

journals.biologists.com/jcs/article/...

07.02.2026 08:18 — 👍 18    🔁 0    💬 1    📌 0
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Theodor Boveri and the natural experiment The philosopher Ludwig Wittengenstein wrote in his Tractatus Logico-Philosophicus that his reader should reach the point where “he must so to speak th…

Over 150 years ago Boveri suggested such events were the source of cancers - www.sciencedirect.com/science/arti...

07.02.2026 08:16 — 👍 29    🔁 1    💬 1    📌 0
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A near-complete map of human cytosolic degrons and their relevance for disease

We measured degron potency of >200,000 30-residue tiles from >5,000 human proteins, and trained a model to predict degrons from sequence

Led by @vvouts.bsky.social in @rhp-lab.bsky.social

doi.org/10.1126/scia...

07.02.2026 07:41 — 👍 53    🔁 17    💬 0    📌 0

Oh I’ve seen these in dishes of senescent RPE1! Figured it was shedding of cellular contents which maintained some level of protein and rna?!

05.02.2026 16:39 — 👍 1    🔁 0    💬 0    📌 0

(It’s a Biobank not a zoo but hey I wouldn’t put it past them)

05.02.2026 08:09 — 👍 0    🔁 0    💬 0    📌 0
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a man wearing glasses says " yeah yeah but your scientists were so preoccupied with whether or not they could ALT: a man wearing glasses says " yeah yeah but your scientists were so preoccupied with whether or not they could

edition.cnn.com/2026/02/04/s...

05.02.2026 08:08 — 👍 0    🔁 0    💬 1    📌 0
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Skiing in Kosovo not bad!

03.02.2026 12:26 — 👍 3    🔁 0    💬 0    📌 0

Except he normally files bankruptcy and refuses to pay his contractors.. let’s see if he can pull that here

31.01.2026 16:59 — 👍 0    🔁 0    💬 0    📌 0

This literally can be said of anything this man has touched since 1980…

31.01.2026 16:50 — 👍 0    🔁 0    💬 1    📌 0

Haha I do!! I’ve avoided AI. Hoping the trend passes 🤣🥹

30.01.2026 09:05 — 👍 0    🔁 0    💬 1    📌 0

And yet it feels like there’s too many papers to read 😂

30.01.2026 08:43 — 👍 1    🔁 0    💬 1    📌 0
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Wise words Melania

30.01.2026 06:20 — 👍 0    🔁 0    💬 0    📌 0

Haha well that’s where I think it’s complicated.

30.01.2026 06:17 — 👍 0    🔁 0    💬 0    📌 0
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Cellular survivorship bias as a mechanistic driver of muscle stem cell aging Aging is characterized by a decline in the ability of tissue repair and regeneration after injury. In skeletal muscle, this decline is largely driven by impaired function of muscle stem cells (MuSCs) ...

This fits my biases in how I imagine tissues age www.science.org/doi/10.1126/...

29.01.2026 20:23 — 👍 1    🔁 0    💬 0    📌 0
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Heritability of intrinsic human life span is about 50% when confounding factors are addressed How heritable is human life span? If genetic heritability is high, longevity genes can reveal aging mechanisms and inform medicine and public health. However, current estimates of heritability are low...

I doubt I’ll understand this but I’ll try - www.science.org/doi/10.1126/...

29.01.2026 20:22 — 👍 1    🔁 0    💬 1    📌 0
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Really excited to share our new paper in @nature.com! We uncovered how a physical instability of the cytoplasm coupled with the cell cycle drives cytoplasmic partitioning in early embryos #zebrafish #drosophila. Read more in this🧵 www.nature.com/articles/s41... 🤩
@poldresden.bsky.social @mpi-cbg.de

28.01.2026 16:10 — 👍 173    🔁 51    💬 3    📌 8
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Population-scale sequencing resolves determinants of persistent EBV DNA - Nature Population-scale WGS reveals genetic determinants of persistent EBV DNA, linking immune regulation—especially antigen processing and MHC class II variation—to EBV persistence and heterogeneous di...

Today in @nature.com, we describe how discarded reads in biobank-scale WGS can help resolve the genetic predictors and consequences of Epstein-Barr Virus (EBV) infection.

Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social

www.nature.com/articles/s41...

28.01.2026 17:07 — 👍 76    🔁 26    💬 4    📌 8
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Environmentally driven immune imprinting protects against allergy - Nature In a mouse model, environmental immunostimulation in early life led to cross-reactive adaptive immune memory and reduced type II immune responses to allergens, indicating a mechanistic relationship be...

www.nature.com/articles/s41...

28.01.2026 16:41 — 👍 9    🔁 4    💬 0    📌 1

Oh I know don’t worry ;)

28.01.2026 13:27 — 👍 1    🔁 0    💬 1    📌 0

You should grab up Paolo machiarini while you’re at it 🤣

28.01.2026 12:33 — 👍 1    🔁 0    💬 1    📌 0

This article is now freely available to everyone in PubMed!
www.ncbi.nlm.nih.gov/pmc/articles...

27.01.2026 12:12 — 👍 2    🔁 2    💬 0    📌 0

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