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Anna Malkowska

@annamalkowska.bsky.social

PhD student in Andrea Brand's lab at NYU Langone and University of Cambridge, studying epigenomics in neural stem cells πŸ§¬πŸ”¬πŸ§ 

77 Followers  |  198 Following  |  4 Posts  |  Joined: 15.11.2024  |  1.4126

Latest posts by annamalkowska.bsky.social on Bluesky

Thank you so much, Maire! πŸ’•

30.06.2025 17:42 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you!

27.05.2025 21:48 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Neural stem cell quiescence is actively maintained by the epigenome Homeostasis and repair of the nervous system is maintained by a population of resident neural stem cells (NSCs) retained in a state of reversible cell cycle arrest called quiescence. quiescent NSCs ca...

Happy to share a preprint of my PhD work! We created a chromatin state model for quiescent and proliferating neural stem cells in Drosophila and found that quiescent cells gain active chromatin to support stem cell functions.
www.biorxiv.org/content/10.1...

16.05.2025 15:51 β€” πŸ‘ 6    πŸ” 0    πŸ’¬ 1    πŸ“Œ 2
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Always on the Move: Overview on Chromatin Dynamics within Nuclear Processes Our genome is organized into chromatin, a dynamic and modular structure made of nucleosomes. Chromatin organization controls access to the DNA sequence, playing a fundamental role in cell identity and...

Want to learn more about chromatin and its dynamics? Read this review by Charlotte and Jolijn in our lab, aimed at giving an overview on this and the ways this is dealt with during transcription, replication and damage repair. Thanks to Biochemistry for inviting us! doi.org/10.1021/acs....

04.05.2025 07:39 β€” πŸ‘ 108    πŸ” 33    πŸ’¬ 2    πŸ“Œ 1
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The importance of moving away from bulk! Occupancy of Pol II at promoters is dramatically different between fly and mouse cells! When looking single molecule! Proud of the team! @kasitc.bsky.social @molinalab.bsky.social doi.org/10.1038/s443...

02.04.2025 08:47 β€” πŸ‘ 115    πŸ” 37    πŸ’¬ 2    πŸ“Œ 1
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Ready to push some flies

21.02.2025 22:07 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Quiescent neural stem cells transiently become 'neurons' to coordinate reactivation Reactivation of quiescent neural stem cells (qNSCs) is a coordinated process that generates new neurons and glia. Here, we show that during development reactivation follows a hierarchical sequence, wh...

✨New✨ Brand lab preprint - Quiescent neural stem cells adopt a transient 'stem cell-neuron' identity to coordinate their reactivation across the CNS. We've been discussing the neuron-like traits of quiescent NSCs for years, so it's been wonderful to see Laura and Jocelyn uncover these mechanisms! ⚑

22.11.2024 10:51 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

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